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NT-PROANP elisa kit :: Goose N-Terminal Pro Atrial Natriuretic Peptide ELISA Kit

Scan QR to view Datasheet Catalog #    MBS014802 NT-PROANP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

N-Terminal Pro Atrial Natriuretic Peptide (NT-PROANP), ELISA Kit

 Also Known As   

Goose N-Terminal Pro Atrial Natriuretic Peptide ELISA Kit

 Product Gene Name   

NT-PROANP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    108780
 3D Structure    ModBase 3D Structure for P01160
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NT-PROANP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NT-PROANP purchase    MBS014802 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the N-Terminal Pro Atrial Natriuretic Peptide (NT-PROANP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NT-PROANP. The ELISA analytical biochemical technique of the MBS014802 kit is based on NT-PROANP antibody-NT-PROANP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NT-PROANP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NT-PROANP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for NT-PROANP. It may not necessarily be applicable to this product.
 NCBI GI #    23510319
 NCBI GeneID    4878
 NCBI Accession #    NP_006163.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006172.3 [Other Products]
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 UniProt Primary Accession #    P01160 [Other Products]
 UniProt Secondary Accession #    Q13766; Q5JZE1 [Other Products]
 UniProt Related Accession #    P01160 [Other Products]
 Molecular Weight    16,708 Da
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 NCBI Official Full Name    natriuretic peptides A preproprotein
 NCBI Official Synonym Full Names    natriuretic peptide A
 NCBI Official Symbol    NPPA [Similar Products]
 NCBI Official Synonym Symbols   
ANF; ANP; PND; ATFB6; ATRST2; CDD-ANF
[Similar Products]
 NCBI Protein Information    natriuretic peptides A; atriopeptin; cardionatrin; prepronatriodilatin; natriuretic peptide precursor A
 UniProt Protein Name    Natriuretic peptides A
 UniProt Synonym Protein Names   
CDD-ANF; PrepronatriodilatinCleaved into the following 2 chains:Cardiodilatin-related peptide; CDPAtrial natriuretic factor; ANF; Alternative name(s):; Atrial natriuretic peptide
 UniProt Gene Name    NPPA [Similar Products]
 UniProt Synonym Gene Names    ANP; PND; CDP; ANF; ANP [Similar Products]
 UniProt Entry Name    ANF_HUMAN
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 NCBI Summary for NT-PROANP    The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq, Sep 2009]
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 UniProt Comments for NT-PROANP    NPPA: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. Defects in NPPA are the cause of familial atrial fibrillation type 6 (ATFB6). Atrial fibrillation is a common disorder of cardiac rhythm that is hereditary in a small subgroup of patients. It is characterized by disorganized atrial electrical activity, progressive deterioration of atrial electromechanical function and ineffective pumping of blood into the ventricles. It can be associated with palpitations, syncope, thromboembolic stroke, and congestive heart failure. Belongs to the natriuretic peptide family.

Protein type: Secreted; Secreted, signal peptide; Hormone

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: extracellular space; mast cell granule; perinuclear region of cytoplasm; extracellular region; nucleus

Molecular Function: neuropeptide hormone activity; peptide hormone receptor binding; receptor binding

Biological Process: cardiac muscle hypertrophy; transcription initiation from RNA polymerase II promoter; cGMP biosynthetic process; neuropeptide signaling pathway; receptor guanylyl cyclase signaling pathway; negative regulation of systemic arterial blood pressure; regulation of blood pressure; response to hypoxia; gene expression; positive regulation of heart rate; female pregnancy; negative regulation of cell growth; regulation of blood vessel size; response to insulin stimulus

Disease: Atrial Standstill 2; Atrial Fibrillation, Familial, 6
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 Research Articles on NT-PROANP    1. the G allele of rs5068 is associated with lower blood pressure, BMI, and prevalence of hypertension and metabolic syndrome in a Mediterranean population
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NT-PROANP elisa kitPathways associated with NT-PROANP elisa kit
 Reference Product  PubMed Publications
 TBX5 elisa kit  >15 publications with NT-PROANP and TBX5
 NPR1 elisa kit  >9 publications with NT-PROANP and NPR1
 NPPC elisa kit  >8 publications with NT-PROANP and NPPC
 NPR3 elisa kit  >5 publications with NT-PROANP and NPR3
 FOS elisa kit  >2 publications with NT-PROANP and FOS
 ADM elisa kit  >1 publications with NT-PROANP and ADM
 EDN1 elisa kit  >1 publications with NT-PROANP and EDN1
 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies  MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram
 YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway antibodies  YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway Diagram
Diseases associated with NT-PROANP elisa kitOrgans/Tissues associated with NT-PROANP elisa kit
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >122 publications with NT-PROANP and Heart Diseases
 Heart Failure Antibodies  >72 publications with NT-PROANP and Heart Failure
 Hypertension Antibodies  >54 publications with NT-PROANP and Hypertension
 Hypertrophy Antibodies  >43 publications with NT-PROANP and Hypertrophy
 Cardiomegaly Antibodies  >32 publications with NT-PROANP and Cardiomegaly
 Kidney Diseases Antibodies  >29 publications with NT-PROANP and Kidney Diseases
 Myocardial Ischemia Antibodies  >25 publications with NT-PROANP and Myocardial Ischemia
 Hypertrophy, Left Ventricular Antibodies  >19 publications with NT-PROANP and Hypertrophy, Left Ventricular
 Cardiomyopathies Antibodies  >15 publications with NT-PROANP and Cardiomyopathies
 Arrhythmias, Cardiac Antibodies  >15 publications with NT-PROANP and Arrhythmias, Cardiac
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >173 publications with NT-PROANP and Heart
 Brain Antibodies  >42 publications with NT-PROANP and Brain
 Lung Antibodies  >21 publications with NT-PROANP and Lung
 Embryonic Tissue Antibodies  >15 publications with NT-PROANP and Embryonic Tissue
 Connective Tissue Antibodies  >5 publications with NT-PROANP and Connective Tissue
 Uterus Antibodies  >2 publications with NT-PROANP and Uterus
 Eye Antibodies  >2 publications with NT-PROANP and Eye
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