Q8VY84.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,047 Da
NCBI Official Full Name
Probable UMP-CMP kinase 1
NCBI Official Synonym Symbols
NCBI Protein Information
uridylate kinase-like protein
UniProt Protein Name
Probable UMP-CMP kinase 1
UniProt Synonym Protein Names
Deoxycytidylate kinase; CK; dCMP kinase; Uridine monophosphate/cytidine monophosphate kinase
UniProt Synonym Gene Names
UniProt Entry Name
KCY1_ARATH
UniProt Comments for P-CK
Function: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors
By similarity. HAMAP-Rule MF_03172
Catalytic activity: ATP + (d)CMP = ADP + (d)CDP. HAMAP-Rule MF_03172ATP + UMP = ADP + UDP. HAMAP-Rule MF_03172
Cofactor: Binds 1 magnesium ion per monomer
By similarity. HAMAP-Rule MF_03172
Subunit structure: Monomer
By similarity. HAMAP-Rule MF_03172
Subcellular location: Cytoplasm
By similarity. Nucleus
By similarity HAMAP-Rule MF_03172.
Domain: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis
By similarity. HAMAP-Rule MF_03172
Sequence similarities: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
Sequence caution: The sequence CAB75933.1 differs from that shown. Reason: Erroneous gene model prediction.
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Pathways associated with P-CK elisa kit
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