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PLSCR2 elisa kit :: Goose Phospholipid Scramblase 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS006130 PLSCR2 elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Phospholipid Scramblase 2 (PLSCR2), ELISA Kit

 Also Known As   

Goose Phospholipid Scramblase 2 ELISA Kit

 Product Gene Name   

PLSCR2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 3; NC_000003.11 (146151075..146213778, complement). Location: 3q24
 OMIM    607610
 3D Structure    ModBase 3D Structure for Q9NRY7
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PLSCR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PLSCR2 purchase    MBS006130 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Phospholipid Scramblase 2 (PLSCR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLSCR2. The ELISA analytical biochemical technique of the MBS006130 kit is based on PLSCR2 antibody-PLSCR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLSCR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLSCR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PLSCR2. It may not necessarily be applicable to this product.
 NCBI GI #    317171906
 NCBI GeneID    57047
 NCBI Accession #    NP_001186908.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199979.1 [Other Products]
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 UniProt Primary Accession #    Q9NRY7 [Other Products]
 UniProt Secondary Accession #    Q0VAQ1; Q6NSW9; B4DXC3; J3KR76 [Other Products]
 UniProt Related Accession #    Q9NRY7 [Other Products]
 Molecular Weight    25,523 Da
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 NCBI Official Full Name    phospholipid scramblase 2 isoform 2
 NCBI Official Synonym Full Names    phospholipid scramblase 2
 NCBI Official Symbol    PLSCR2 [Similar Products]
 NCBI Protein Information    phospholipid scramblase 2; PL scramblase 2; ca(2+)-dependent phospholipid scramblase 2
 UniProt Protein Name    Phospholipid scramblase 2
 UniProt Synonym Protein Names   
Ca(2+)-dependent phospholipid scramblase 2
 Protein Family    Phospholipid scramblase
 UniProt Gene Name    PLSCR2 [Similar Products]
 UniProt Synonym Gene Names    PL scramblase 2 [Similar Products]
 UniProt Entry Name    PLS2_HUMAN
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 NCBI Summary for PLSCR2    This gene encodes a member of the phospholipid scramblase family. Phospholipid scramblases are membrane proteins that mediate calcium-dependent, non-specific movement of plasma membrane phospholipids and phosphatidylserine exposure. The encoded protein contains a low affinity calcium binding motif and may play a role in blood coagulation and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
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 UniProt Comments for PLSCR2    PLSCR2: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family.

Chromosomal Location of Human Ortholog: 3q24

Cellular Component: plasma membrane; integral to membrane; nucleus

Molecular Function: phospholipid scramblase activity; calcium ion binding

Biological Process: phospholipid scrambling
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 Research Articles on PLSCR2    1. Results show that binding affinities of the peptides are in the order hPLSCR1>hPLSCR3>hPLSCR2>hPLSCR4 for Ca2+ and in the order hPLSCR1>hPLSCR2>hPLSCR3>hPLSCR4 for Mg2+.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PLSCR2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with PLSCR2 and Inflammation
 Breast Neoplasms Antibodies  >1 publications with PLSCR2 and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with PLSCR2 and Disease Models, Animal
 Drug Toxicity Antibodies  >1 publications with PLSCR2 and Drug Toxicity
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