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PRSS12 elisa kit :: Goose Protease, Serine 12 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS029683 PRSS12 elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Protease, Serine 12 (PRSS12), ELISA Kit

 Also Known As   

Goose Protease, Serine 12 ELISA Kit

 Product Gene Name   

PRSS12 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 4; NC_000004.11 (119201193..119273922, complement). Location: 4q28.1
 OMIM    249500
 3D Structure    ModBase 3D Structure for P56730
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PRSS12 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PRSS12 purchase    MBS029683 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protease, Serine 12 (PRSS12) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PRSS12. The ELISA analytical biochemical technique of the MBS029683 kit is based on PRSS12 antibody-PRSS12 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PRSS12 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PRSS12. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PRSS12. It may not necessarily be applicable to this product.
 NCBI GI #    14043559
 NCBI GeneID    8492
 NCBI Accession #    AAH07761.1 [Other Products]
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 UniProt Primary Accession #    P56730 [Other Products]
 UniProt Secondary Accession #    Q9UP16 [Other Products]
 UniProt Related Accession #    P56730 [Other Products]
 Molecular Weight    97,067 Da
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 NCBI Official Full Name    PRSS12 protein
 NCBI Official Synonym Full Names    protease, serine, 12 (neurotrypsin, motopsin)
 NCBI Official Symbol    PRSS12 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    neurotrypsin; leydin; brain-specific serine protease 3
 UniProt Protein Name    Neurotrypsin
 UniProt Synonym Protein Names   
Leydin; Motopsin; Serine protease 12
 Protein Family    Neurotrypsin
 UniProt Gene Name    PRSS12 [Similar Products]
 UniProt Entry Name    NETR_HUMAN
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 NCBI Summary for PRSS12    This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). [provided by RefSeq, Jul 2010]
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 UniProt Comments for PRSS12    PRSS12: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Defects in PRSS12 are the cause of mental retardation autosomal recessive type 1 (MRT1). Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the peptidase S1 family.

Protein type: Vesicle; Secreted; EC 3.4.21.-; Secreted, signal peptide; Protease

Chromosomal Location of Human Ortholog: 4q28.1

Cellular Component: axon; dendrite; plasma membrane; extracellular region; terminal button; cytoplasmic vesicle

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; exocytosis; zymogen activation; proteolysis

Disease: Mental Retardation, Autosomal Recessive 1
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 Research Articles on PRSS12    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PRSS12 elisa kitOrgans/Tissues associated with PRSS12 elisa kit
 Reference Product  PubMed Publications
 CRBN elisa kit  >2 publications with PRSS12 and CRBN
 CC2D1A elisa kit  >2 publications with PRSS12 and CC2D1A
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with PRSS12 and Brain
 Vascular Antibodies  >1 publications with PRSS12 and Vascular
 Bone Antibodies  >1 publications with PRSS12 and Bone
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