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TBX3 elisa kit :: Goose T-Box Protein 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS020399 TBX3 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

T-Box Protein 3 (TBX3), ELISA Kit

 Also Known As   

Goose T-Box Protein 3 ELISA Kit

 Product Gene Name   

TBX3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    181450
 3D Structure    ModBase 3D Structure for O15119
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of TBX3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TBX3 purchase    MBS020399 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the T-Box Protein 3 (TBX3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TBX3. The ELISA analytical biochemical technique of the MBS020399 kit is based on TBX3 antibody-TBX3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TBX3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TBX3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TBX3. It may not necessarily be applicable to this product.
 NCBI GI #    47419907
 NCBI GeneID    6926
 NCBI Accession #    NP_057653.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_016569.3 [Other Products]
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 UniProt Primary Accession #    O15119 [Other Products]
 UniProt Secondary Accession #    Q8TB20; Q9UKF8 [Other Products]
 UniProt Related Accession #    O15119 [Other Products]
 Molecular Weight    79,389 Da
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 NCBI Official Full Name    T-box transcription factor TBX3 isoform 2
 NCBI Official Synonym Full Names    T-box 3
 NCBI Official Symbol    TBX3 [Similar Products]
 NCBI Official Synonym Symbols   
UMS; XHL; TBX3-ISO
[Similar Products]
 NCBI Protein Information    T-box transcription factor TBX3; T-box protein 3; bladder cancer related protein XHL
 UniProt Protein Name    T-box transcription factor TBX3
 Protein Family    T-box transcription factor
 UniProt Gene Name    TBX3 [Similar Products]
 UniProt Synonym Gene Names    T-box protein 3 [Similar Products]
 UniProt Entry Name    TBX3_HUMAN
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 NCBI Summary for TBX3    This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TBX3    TBX3: Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS). UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 12q24.21

Cellular Component: nucleus

Molecular Function: protein binding; sequence-specific DNA binding

Biological Process: embryonic forelimb morphogenesis; positive regulation of transcription, DNA-dependent; limbic system development; negative regulation of epithelial cell differentiation; negative regulation of transcription from RNA polymerase II promoter; palate development; female genitalia development; forelimb morphogenesis; mammary gland development; determination of anterior/posterior axis, embryo; positive regulation of cell proliferation; male genitalia development; heart looping; skeletal development; luteinizing hormone secretion; blood vessel development; specification of organ position; transcription, DNA-dependent; in utero embryonic development; stem cell maintenance; cell aging; positive regulation of cell cycle; regulation of transcription from RNA polymerase II promoter; organ morphogenesis; mesoderm morphogenesis; embryonic digit morphogenesis; follicle-stimulating hormone secretion; negative regulation of myoblast differentiation; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis

Disease: Ulnar-mammary Syndrome
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 Research Articles on TBX3    1. TBX3 may play an important role as a reciprocal switch between substrate dependent cell proliferation and tumour invasion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TBX3 elisa kitDiseases associated with TBX3 elisa kit
 Reference Product  PubMed Publications
 BMP4 elisa kit  >11 publications with TBX3 and BMP4
 CDKN2A elisa kit  >8 publications with TBX3 and CDKN2A
 GATA6 elisa kit  >6 publications with TBX3 and GATA6
 MSX2 elisa kit  >3 publications with TBX3 and MSX2
 HDAC1 elisa kit  >2 publications with TBX3 and HDAC1
 SOX4 elisa kit  >1 publications with TBX3 and SOX4
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >58 publications with TBX3 and Neoplasms
 Ulnar-mammary syndrome Antibodies  >50 publications with TBX3 and Ulnar-mammary syndrome
 Cardiovascular Diseases Antibodies  >23 publications with TBX3 and Cardiovascular Diseases
 Heart Diseases Antibodies  >23 publications with TBX3 and Heart Diseases
 Breast Neoplasms Antibodies  >18 publications with TBX3 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >7 publications with TBX3 and Neoplasms, Experimental
 Liver Diseases Antibodies  >6 publications with TBX3 and Liver Diseases
 Limb Deformities, Congenital Antibodies  >6 publications with TBX3 and Limb Deformities, Congenital
 Carcinoma, Hepatocellular Antibodies  >5 publications with TBX3 and Carcinoma, Hepatocellular
 Tooth Abnormalities Antibodies  >4 publications with TBX3 and Tooth Abnormalities
Organs/Tissues associated with TBX3 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >78 publications with TBX3 and Heart
 Embryonic Tissue Antibodies  >52 publications with TBX3 and Embryonic Tissue
 Mammary Gland Antibodies  >29 publications with TBX3 and Mammary Gland
 Brain Antibodies  >17 publications with TBX3 and Brain
 Nerve Antibodies  >14 publications with TBX3 and Nerve
 Liver Antibodies  >13 publications with TBX3 and Liver
 Eye Antibodies  >10 publications with TBX3 and Eye
 Skin Antibodies  >9 publications with TBX3 and Skin
 Lung Antibodies  >8 publications with TBX3 and Lung
 Bladder Antibodies  >5 publications with TBX3 and Bladder
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