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HSD17B6 elisa kit :: Guinea Pig 17-beta-hydroxysteroid dehydrogenase type 6 (HSD17B6) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7238850 HSD17B6 elisa kit
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

17-beta-hydroxysteroid dehydrogenase type 6 (HSD17B6), ELISA Kit

 Also Known As   

Guinea pig 17-beta-hydroxysteroid dehydrogenase type 6 (HSD17B6) ELISA Kit

 Product Gene Name   

HSD17B6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    606623
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 Species Reactivity    Guinea Pig
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    1.0-25ng/mL
 Sensitivity    0.1ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HSD17B6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HSD17B6 purchase    MBS7238850 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 17-beta-hydroxysteroid dehydrogenase type 6 (HSD17B6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.0-25ng/mL in biological research samples containing HSD17B6, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS7238850 kit is based on HSD17B6 antibody-HSD17B6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HSD17B6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HSD17B6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for HSD17B6 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for HSD17B6. It may not necessarily be applicable to this product.
 NCBI GI #    19743808
 NCBI GeneID    8630
 NCBI Accession #    NP_003716.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003725.3 [Other Products]
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 UniProt Secondary Accession #    O43275 [Other Products]
 UniProt Related Accession #    O14756 [Other Products]
 Molecular Weight    35,966 Da [Similar Products]
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 NCBI Official Full Name    17-beta-hydroxysteroid dehydrogenase type 6
 NCBI Official Synonym Full Names    hydroxysteroid (17-beta) dehydrogenase 6
 NCBI Official Symbol    HSD17B6 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    17-beta-hydroxysteroid dehydrogenase type 6; 17-beta-HSD 6; oxidoreductase; 3-alpha->beta-HSE; retinol dehydrogenase; 3-hydroxysteroid epimerase; 3-alpha->beta-hydroxysteroid epimerase; 3(alpha->beta)-hydroxysteroid epimerase; 3(alpha->beta)-hydroxysteroid epimerasel; oxidative 3-alpha hydroxysteroid dehydrogenase; oxidative 3-alpha-hydroxysteroid-dehydrogenase; hydroxysteroid (17-beta) dehydrogenase 6 homolog; short chain dehydrogenase/reductase family 9C, member 6; NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase
 UniProt Protein Name    17-beta-hydroxysteroid dehydrogenase type 6
 UniProt Synonym Protein Names   
3-alpha->beta-hydroxysteroid epimerase; 3-alpha->beta-HSE; Oxidative 3-alpha hydroxysteroid dehydrogenase
 Protein Family    17-beta-hydroxysteroid dehydrogenase
 UniProt Gene Name    HSD17B6 [Similar Products]
 UniProt Synonym Gene Names    RODH; 17-beta-HSD 6; 17-beta-HSD6; 3-alpha->beta-HSE [Similar Products]
 UniProt Entry Name    H17B6_HUMAN
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 NCBI Summary for HSD17B6    The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]
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 UniProt Comments for HSD17B6    HSD17B6: NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3- alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha- androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: EC; Oxidoreductase; EC; EC

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: endoplasmic reticulum; early endosome membrane; intracellular

Molecular Function: estradiol 17-beta-dehydrogenase activity; electron carrier activity; oxidoreductase activity; catalytic activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity; retinol dehydrogenase activity

Biological Process: androgen biosynthetic process; androgen catabolic process
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 Research Articles on HSD17B6    1. the CYP11A1, CYP17A1, HSD3B2, SRD5A2, and HSD17B6 mRNA levels in metastases were significantly lower.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HSD17B6 elisa kitPathways associated with HSD17B6 elisa kit
 Reference Product  PubMed Publications
 CYP19A1 elisa kit  >2 publications with HSD17B6 and CYP19A1
 SRD5A2 elisa kit  >1 publications with HSD17B6 and SRD5A2
 HSD3B2 elisa kit  >1 publications with HSD17B6 and HSD3B2
 CYP1B1 elisa kit  >1 publications with HSD17B6 and CYP1B1
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway antibodies  The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway Diagram
 Visual Phototransduction Pathway antibodies  Visual Phototransduction Pathway Diagram
Diseases associated with HSD17B6 elisa kitOrgans/Tissues associated with HSD17B6 elisa kit
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >1 publications with HSD17B6 and Mental Disorders
 Cardiovascular Diseases Antibodies  >1 publications with HSD17B6 and Cardiovascular Diseases
 Hyperplasia Antibodies  >1 publications with HSD17B6 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >6 publications with HSD17B6 and Prostate
 Ovary Antibodies  >4 publications with HSD17B6 and Ovary
 Uterus Antibodies  >2 publications with HSD17B6 and Uterus
 Kidney Antibodies  >1 publications with HSD17B6 and Kidney
 Embryonic Tissue Antibodies  >1 publications with HSD17B6 and Embryonic Tissue
 Brain Antibodies  >1 publications with HSD17B6 and Brain
 Liver Antibodies  >1 publications with HSD17B6 and Liver
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