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ADAM10 elisa kit :: Guinea Pig A Disintegrin And Metalloprotease 10 (ADAM10) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS269835 ADAM10 elisa kit
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloprotease 10 (ADAM10), ELISA Kit

★Popular Item★
 Also Known As   

Guinea pig A Disintegrin And Metalloprotease 10 (ADAM10) ELISA Kit

 Product Gene Name   

ADAM10 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    608990
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 Species Reactivity    Guinea Pig
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADAM10 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADAM10 purchase    MBS269835 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin And Metalloprotease 10 (ADAM10) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADAM10. The ELISA analytical biochemical technique of the MBS269835 kit is based on ADAM10 antibody-ADAM10 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAM10 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAM10. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ADAM10. It may not necessarily be applicable to this product.
 NCBI GI #    537544566
 NCBI GeneID    81794
 NCBI Accession #    NP_112219.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_030957.3 [Other Products]
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 UniProt Secondary Accession #    M0QZE4 [Other Products]
 UniProt Related Accession #    Q9H324 [Other Products]
 Molecular Weight    62,530 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif, 10
 NCBI Official Symbol    ADAMTS10 [Similar Products]
 NCBI Official Synonym Symbols   
WMS; WMS1; ADAM-TS10; ADAMTS-10
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM-TS 10; zinc metalloendopeptidase; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 10
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    ADAMTS10 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 10; ADAM-TS10; ADAMTS-10 [Similar Products]
 UniProt Entry Name    ATS10_HUMAN
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 NCBI Summary for ADAM10    This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAM10    ADAMTS10: Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues. Defects in ADAMTS10 are the cause of Weill-Marchesani syndrome 1 (WMS1). WMS1 is a rare connective tissue disorder characterized by short stature, brachydactyly, joint stiffness, and eye abnormalities including microspherophakia, ectopia lentis, severe myopia and glaucoma.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; EC 3.4.24.-; Protease

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular matrix; microfibril

Molecular Function: protein binding; zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis

Disease: Weill-marchesani Syndrome 1
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 Research Articles on ADAM10    1. These findings support the Gly661Arg mutation of ADAMTS10 as the likely cause of POAG in beagles.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADAM10 elisa kitPathways associated with ADAM10 elisa kit
 Reference Product  PubMed Publications
 FBN1 elisa kit  >11 publications with ADAM10 and FBN1
 LTBP1 elisa kit  >1 publications with ADAM10 and LTBP1
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-glycosylation Of TSR Domain-containing Proteins Pathway antibodies  O-glycosylation Of TSR Domain-containing Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
Diseases associated with ADAM10 elisa kitOrgans/Tissues associated with ADAM10 elisa kit
 Disease Name  Pubmed Publications
 Weill-Marchesani Syndrome Antibodies  >15 publications with ADAM10 and Weill-Marchesani Syndrome
 Pregnancy Complications Antibodies  >1 publications with ADAM10 and Pregnancy Complications
 Kidney Diseases Antibodies  >1 publications with ADAM10 and Kidney Diseases
 Heart Diseases Antibodies  >1 publications with ADAM10 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >11 publications with ADAM10 and Eye
 Skin Antibodies  >3 publications with ADAM10 and Skin
 Blood Antibodies  >3 publications with ADAM10 and Blood
 Heart Antibodies  >2 publications with ADAM10 and Heart
 Kidney Antibodies  >2 publications with ADAM10 and Kidney
 Nerve Antibodies  >1 publications with ADAM10 and Nerve
 Lung Antibodies  >1 publications with ADAM10 and Lung
 Embryonic Tissue Antibodies  >1 publications with ADAM10 and Embryonic Tissue
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