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ADA elisa kit :: Guinea Pig Adenosine Deaminase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS720987
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Adenosine Deaminase (ADA), ELISA Kit

 Also Known As   

Guinea pig Adenosine Deaminase ELISA Kit

 Product Gene Name   

ADA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    608958
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 Species Reactivity    Guinea Pig
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADA purchase    MBS720987 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Adenosine Deaminase (ADA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADA. The ELISA analytical biochemical technique of the MBS720987 kit is based on ADA antibody-ADA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of ADA elisa kit    ADA elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS720987. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ADA. It may not necessarily be applicable to this product.
 NCBI GI #    47078295
 NCBI GeneID    100
 NCBI Accession #    NP_000013.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000022.2 [Other Products]
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 UniProt Secondary Accession #    Q53F92; Q6LA59 [Other Products]
 UniProt Related Accession #    P00813 [Other Products]
 Molecular Weight    40,764 Da
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 NCBI Official Full Name    adenosine deaminase
 NCBI Official Synonym Full Names    adenosine deaminase
 NCBI Official Symbol    ADA [Similar Products]
 NCBI Protein Information    adenosine deaminase; adenosine aminohydrolase
 UniProt Protein Name    Adenosine deaminase
 UniProt Synonym Protein Names   
Adenosine aminohydrolase
 Protein Family    Adenosine deaminase
 UniProt Gene Name    ADA [Similar Products]
 UniProt Synonym Gene Names    ADA1 [Similar Products]
 UniProt Entry Name    ADA_HUMAN
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 NCBI Summary for ADA    This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADA    ADA: a enzyme that converts adenosine + H2O into inosine + NH3. Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues. Genetic ADA deficiencies are a cause of autosomal recessive severe combined immuno-deficiency (SCID). Hereditary hemolytic anemia is caused by expression levels in erythrocytes 50-70 times greater than the norm.

Protein type: EC 3.5.4.4; Nucleotide Metabolism - purine; Hydrolase

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: dendrite cytoplasm; extracellular space; cell surface; membrane; cell soma; lysosome; cytoplasm; plasma membrane; cell junction; cytosol; external side of plasma membrane

Molecular Function: adenosine deaminase activity; protein binding; zinc ion binding; purine nucleoside binding

Biological Process: negative regulation of circadian sleep/wake cycle, non-REM sleep; T cell activation; adenosine catabolic process; deoxyadenosine catabolic process; response to morphine; positive regulation of calcium-mediated signaling; purine salvage; positive regulation of T cell differentiation in the thymus; histamine secretion; purine ribonucleoside monophosphate biosynthetic process; regulation of cell-cell adhesion mediated by integrin; response to vitamin E; negative regulation of mature B cell apoptosis; positive regulation of T cell receptor signaling pathway; positive regulation of B cell proliferation; positive regulation of germinal center formation; hypoxanthine salvage; negative regulation of adenosine receptor signaling pathway; positive regulation of smooth muscle contraction; embryonic gut development; placenta development; aging; Peyer's patch development; response to drug; dATP catabolic process; nucleobase, nucleoside and nucleotide metabolic process; positive regulation of heart rate; liver development; negative regulation of leukocyte migration; purine base metabolic process; trophectodermal cell differentiation; purine nucleotide salvage; response to hydrogen peroxide; xanthine biosynthetic process; negative regulation of inflammatory response; response to hypoxia; inosine biosynthetic process; germinal center B cell differentiation; alveolus development; positive regulation of alpha-beta T cell differentiation

Disease: Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-negative, B Cell-negative, Nk Cell-negative, Due To Adenosine Deaminase Deficiency
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 Research Articles on ADA    1. In Class 3 people the combination of high ACP f-isozyme concentration and the ADA*2 allele, lowers the rate of glycolysis that may reduce the amount of metabolic calories and activates Sirtuin genes that protect cells against age-related diseases.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADA elisa kitPathways associated with ADA elisa kit
 Reference Product  PubMed Publications
 PNP elisa kit  >157 publications with ADA and PNP
 ADORA1 elisa kit  >71 publications with ADA and ADORA1
 DPP4 elisa kit  >22 publications with ADA and DPP4
 DCK elisa kit  >10 publications with ADA and DCK
 MYB elisa kit  >6 publications with ADA and MYB
 NT5E elisa kit  >3 publications with ADA and NT5E
 ADK elisa kit  >3 publications with ADA and ADK
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Salvage Pathway antibodies  Purine Salvage Pathway Diagram
Diseases associated with ADA elisa kitOrgans/Tissues associated with ADA elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >451 publications with ADA and Nervous System Diseases
 Brain Diseases Antibodies  >221 publications with ADA and Brain Diseases
 Heart Diseases Antibodies  >200 publications with ADA and Heart Diseases
 Inflammation Antibodies  >198 publications with ADA and Inflammation
 Necrosis Antibodies  >193 publications with ADA and Necrosis
 Hypertension Antibodies  >167 publications with ADA and Hypertension
 Disease Models, Animal Antibodies  >131 publications with ADA and Disease Models, Animal
 Pain Antibodies  >109 publications with ADA and Pain
 Liver Diseases Antibodies  >97 publications with ADA and Liver Diseases
 Kidney Diseases Antibodies  >81 publications with ADA and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2414 publications with ADA and Blood
 Bone Antibodies  >320 publications with ADA and Bone
 Heart Antibodies  >264 publications with ADA and Heart
 Brain Antibodies  >264 publications with ADA and Brain
 Bone Marrow Antibodies  >227 publications with ADA and Bone Marrow
 Lung Antibodies  >218 publications with ADA and Lung
 Liver Antibodies  >212 publications with ADA and Liver
 Spleen Antibodies  >156 publications with ADA and Spleen
 Kidney Antibodies  >153 publications with ADA and Kidney
 Thymus Antibodies  >135 publications with ADA and Thymus
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