NP_003559.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,364 Da
NCBI Official Full Name
annexin A9
NCBI Official Synonym Full Names
annexin A9
NCBI Official Synonym Symbols
NCBI Protein Information
annexin A9; annexin-9; pemphaxin; annexin 31; annexin-31; annexin XXXI
UniProt Protein Name
Annexin A9
UniProt Synonym Protein Names
Annexin XXXI; Annexin-31; Annexin-9; Pemphaxin
UniProt Synonym Gene Names
UniProt Entry Name
ANXA9_HUMAN
NCBI Summary for ANXA9
The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. [provided by RefSeq, Jul 2008]
UniProt Comments for ANXA9
ANXA9: a calcium/phospholipid-binding protein that may act as a low affinity receptor for acetylcholine. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Lipid-binding; Calcium-binding
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: cell surface; cytosol
Molecular Function: protein binding; protein homodimerization activity; calcium-dependent phospholipid binding; phosphatidylserine binding; acetylcholine receptor activity; phospholipid binding; calcium ion binding
Biological Process: synaptic transmission; cell-cell adhesion
Research Articles on ANXA9
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Diseases associated with ANXA9 elisa kit
Organs/Tissues associated with ANXA9 elisa kit
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