Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow CD40L rightarrow Guinea Pig CD40L  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Rhinovirus Antigen (RHVAg) ELISA Kit
 • Glutathione Peroxidase 1 (GPX1) ELISA Kit
 • Octyl-beta-D-thioglucopyran oside Biochemical
 • PAX8 Antibody
 • Echovirus 4 Antibody
 • CD28 Antibody
 • Krebs Von Den Lungen 6 (KL-6) ELISA Kit
 • Neurocalcin Delta (NCALD) Recombinant Protein
 • Inhibin (INH) ELISA Kit
 • Erythropoitin (EPO) ELISA Kit
 • FGF23 Antibody
 • V-Set Domain Containing T-Cell Activation Inhibitor 1 (VTCN1... ELISA Kit
 • APLN Antibody
 • EED ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CD40L elisa kit :: Guinea Pig CD 40 Ligand ELISA Kit

Scan QR to view Datasheet Catalog #    MBS720773
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD 40 Ligand (CD40L), ELISA Kit

 Also Known As   

Guinea pig CD 40 Ligand ELISA Kit

 Product Gene Name   

CD40L elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 308230
Section Bar
 Species Reactivity    Guinea Pig
Section Bar
Section Bar
 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    50-1000pg/mL
 Sensitivity    1.0pg/mL
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CD40L elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CD40L purchase    MBS720773 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD 40 Ligand (CD40L) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 50-1000pg/mL in biological research samples containing CD40L, with an estimated sensitivity of 1.0pg/mL. The ELISA analytical biochemical technique of the MBS720773 kit is based on CD40L antibody-CD40L antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD40L antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD40L. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 Product Categories/Family for CD40L elisa kit    Immunology
Section Bar
 Typical Testing Data/Standard Curve (for reference only) of CD40L elisa kit    CD40L elisa kit Typical Testing Data/Standard Curve (for reference only) image
Table BarTOPTable Bar
Sample Manual Insert of MBS720773. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CD40L. It may not necessarily be applicable to this product.
 NCBI GI #    4557433
 NCBI GeneID    959
 NCBI Accession #    NP_000065.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000074.2 [Other Products]
Section Bar
 UniProt Related Accession #    P29965 [Other Products]
 Molecular Weight    29,274 Da
Table BarTOPTable Bar
 NCBI Official Full Name    CD40 ligand
 NCBI Official Synonym Full Names    CD40 ligand
 NCBI Official Symbol    CD40LG [Similar Products]
 NCBI Official Synonym Symbols   
IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
[Similar Products]
 NCBI Protein Information    CD40 ligand; CD40-L; CD40 antigen ligand; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5
 UniProt Protein Name    CD40 ligand
 UniProt Synonym Protein Names   
T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD_antigen: CD154Cleaved into the following 2 chains:CD40 ligand, membrane form; CD40 ligand, soluble form
 UniProt Gene Name    CD40LG [Similar Products]
 UniProt Synonym Gene Names    CD40L; TNFSF5; TRAP; CD40-L; TRAP [Similar Products]
 UniProt Entry Name    CD40L_HUMAN
Section Bar
 NCBI Summary for CD40L    The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for CD40L    CD40LG: Mediates B-cell proliferation in the absence of co- stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Defects in CD40LG are the cause of X-linked immunodeficiency with hyper-IgM type 1 (HIGM1); also known as X-linked hyper IgM syndrome (XHIM). HIGM1 is an immunoglobulin isotype switch defect characterized by elevated concentrations of serum IgM and decreased amounts of all other isotypes. Affected males present at an early age (usually within the first year of life) recurrent bacterial and opportunistic infections, including Pneumocystis carinii pneumonia and intractable diarrhea due to cryptosporidium infection. Despite substitution treatment with intravenous immunoglobulin, the overall prognosis is rather poor, with a death rate of about 10% before adolescence. Belongs to the tumor necrosis factor family.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq26

Cellular Component: extracellular space; integral to plasma membrane; plasma membrane; integral to membrane; external side of plasma membrane

Molecular Function: cytokine activity; CD40 receptor binding; tumor necrosis factor receptor binding

Biological Process: B cell proliferation; platelet activation; leukocyte adhesion; regulation of immune response; positive regulation of interleukin-12 production; B cell differentiation; immunoglobulin secretion; isotype switching; inflammatory response; regulation of immunoglobulin secretion; negative regulation of apoptosis

Disease: Immunodeficiency With Hyper-igm, Type 1
Table BarTOPTable Bar
 Research Articles on CD40L    1. CD40L/CD40 could inhibit human glioma cells.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with CD40L elisa kitPathways associated with CD40L elisa kit
 Reference Product  PubMed Publications
 CD40 elisa kit  >28 publications with CD40L and CD40
 ICAM1 elisa kit  >4 publications with CD40L and ICAM1
 CD86 elisa kit  >4 publications with CD40L and CD86
 TRAF1 elisa kit  >2 publications with CD40L and TRAF1
 RELA elisa kit  >1 publications with CD40L and RELA
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 CD40/CD40L Signaling Pathway antibodies  CD40/CD40L Signaling Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
Diseases associated with CD40L elisa kitOrgans/Tissues associated with CD40L elisa kit
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >11 publications with CD40L and Autoimmune Diseases
 Inflammation Antibodies  >9 publications with CD40L and Inflammation
 Necrosis Antibodies  >6 publications with CD40L and Necrosis
 Cardiovascular Diseases Antibodies  >4 publications with CD40L and Cardiovascular Diseases
 Myocardial Infarction Antibodies  >3 publications with CD40L and Myocardial Infarction
 Hyper-IgM Immunodeficiency Syndrome, Type 1 Antibodies  >3 publications with CD40L and Hyper-IgM Immunodeficiency Syndrome, Type 1
 Myocardial Ischemia Antibodies  >3 publications with CD40L and Myocardial Ischemia
 Pneumonia Antibodies  >3 publications with CD40L and Pneumonia
 Heart Diseases Antibodies  >3 publications with CD40L and Heart Diseases
 Kidney Diseases Antibodies  >2 publications with CD40L and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >33 publications with CD40L and Blood
 Mixed Antibodies  >1 publications with CD40L and Mixed
 Thymus Antibodies  >1 publications with CD40L and Thymus
 Brain Antibodies  >1 publications with CD40L and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions