CAG38751.1
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,583 Da
NCBI Official Full Name
TRIP10
NCBI Official Synonym Full Names
thyroid hormone receptor interactor 10
NCBI Protein Information
cdc42-interacting protein 4; protein Felic; salt tolerator; salt tolerant protein; TR-interacting protein 10; thyroid receptor-interacting protein 10
UniProt Protein Name
Cdc42-interacting protein 4
UniProt Synonym Protein Names
Protein Felic; Salt tolerant protein; hSTP; Thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
UniProt Synonym Gene Names
UniProt Entry Name
CIP4_HUMAN
UniProt Comments for TRIP10
TRIP10: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. Belongs to the FNBP1 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold; Nuclear receptor co-regulator; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleoplasm; Golgi apparatus; cell projection; cytoskeleton; intracellular membrane-bound organelle; lysosome; perinuclear region of cytoplasm; cytoplasm; cell cortex; cytosol; phagocytic cup
Molecular Function: identical protein binding; protein binding; lipid binding
Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; endocytosis; cell communication; signal transduction; actin cytoskeleton organization and biogenesis
Research Articles on TRIP10
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with TRIP10 elisa kit
Diseases associated with TRIP10 elisa kit
Organs/Tissues associated with TRIP10 elisa kit
|