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CDK-2 elisa kit :: Guinea Pig Cyclin Dependent Kinase 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS732051 CDK-2 elisa kit
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cyclin Dependent Kinase 2 (CDK-2), ELISA Kit

 Also Known As   

Guinea pig Cyclin Dependent Kinase 2 ELISA Kit

 Product Gene Name   

CDK-2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Guinea Pig
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    0.5-10ng/mL
 Sensitivity    0.1ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CDK-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CDK-2 purchase    MBS732051 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cyclin Dependent Kinase 2 (CDK-2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.5-10ng/mL in biological research samples containing CDK-2, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS732051 kit is based on CDK-2 antibody-CDK-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CDK-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CDK-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CDK-2 elisa kit    Cell Biology
NCBI/Uniprot data below describe general gene information for CDK-2. It may not necessarily be applicable to this product.
 NCBI GI #    41054836
 NCBI GeneID    362817
 NCBI Accession #    NP_955795.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_199501.1 [Other Products]
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 UniProt Secondary Accession #    O09136 [Other Products]
 UniProt Related Accession #    Q63699 [Other Products]
 Molecular Weight    – Da
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 NCBI Official Full Name    cyclin-dependent kinase 2
 NCBI Official Synonym Full Names    cyclin dependent kinase 2
 NCBI Official Symbol    Cdk2 [Similar Products]
 NCBI Protein Information    cyclin-dependent kinase 2; cell division protein kinase 2; cyclin dependent kinase 2-alpha
 UniProt Protein Name    Cyclin-dependent kinase 2
 UniProt Synonym Protein Names   
Cell division protein kinase 2
 UniProt Gene Name    Cdk2 [Similar Products]
 UniProt Synonym Gene Names    Cdkn2 [Similar Products]
 UniProt Entry Name    CDK2_RAT
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 UniProt Comments for CDK-2    CDK2: a protein kinase of the CDK family. An important component of the cell cycle machinery. Activity of CDK2 is maximal during S phase and G2. Cdk2/cyclin E kinase activity is important for the G1 to S transition and phosphorylates the Rb protein. In S-phase, active cdk2/cyclin A complexes predominate and phosphorylate E2F, and the active cdk2 complex persists in the nucleus through G2. Part of the Rb pathway disregulated in most tumors. Target of several candidate cancer drugs. However, inhibition does not always prevent cancer cell growth, possibly due to CDK redundancy. Inhibitors: BMS-265246, BMS-265246-01, R-roscovitine (CYC200, CYC202), SU9516, R547, L868276

Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; CMGC group; CDK family; CDK1 subfamily; CDK/CDK1 subfamily

Cellular Component: Y chromosome; Cajal body; transcription factor complex; chromosome, telomeric region; intracellular membrane-bound organelle; X chromosome; cytoplasm; cyclin-dependent protein kinase holoenzyme complex; microtubule organizing center; condensed chromosome; nucleus; cytosol; endosome

Molecular Function: cyclin binding; cyclin-dependent protein kinase activity; metal ion binding; protein complex binding; histone kinase activity; kinase activity; ATP binding; protein kinase activity

Biological Process: lens development in camera-type eye; response to drug; mitosis; organ regeneration; response to cAMP; regulation of cell cycle; response to toxin; positive regulation of transcription, DNA-dependent; histone phosphorylation; DNA repair; protein amino acid phosphorylation; response to estradiol stimulus; peptidyl-serine phosphorylation; response to ethanol; response to cadmium ion; meiotic cell cycle; cellular response to insulin stimulus; cell division; positive regulation of cell proliferation; Ras protein signal transduction; response to electrical stimulus; potassium ion transport; G1/S transition of mitotic cell cycle; positive regulation of DNA replication initiation
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 Research Articles on CDK-2    1. The Irf-1 overexpression-induced proliferation of VSMCs, the up-regulation of cyclin E/CDK2 and the acceleration of cell cycle progression are associated with ROS/Erk1/2 signaling pathway under high glucose conditions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CDK-2 elisa kitOrgans/Tissues associated with CDK-2 elisa kit
 Products by Pathway  Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 ATM Pathway antibodies  ATM Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 CDK-mediated Phosphorylation And Removal Of Cdc6 Pathway antibodies  CDK-mediated Phosphorylation And Removal Of Cdc6 Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >291 publications with CDK-2 and Liver
 Lung Antibodies  >235 publications with CDK-2 and Lung
 Prostate Antibodies  >165 publications with CDK-2 and Prostate
 Brain Antibodies  >159 publications with CDK-2 and Brain
 Colon Antibodies  >148 publications with CDK-2 and Colon
 Embryonic Tissue Antibodies  >96 publications with CDK-2 and Embryonic Tissue
 Heart Antibodies  >81 publications with CDK-2 and Heart
 Thymus Antibodies  >31 publications with CDK-2 and Thymus
 Spleen Antibodies  >31 publications with CDK-2 and Spleen
 Pancreas Antibodies  >25 publications with CDK-2 and Pancreas
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