ADI49832.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,434 Da
NCBI Official Full Name
granulocyte colony-stimulating factor, partial
NCBI Official Synonym Full Names
colony stimulating factor 3 (granulocyte)
NCBI Protein Information
granulocyte colony-stimulating factor; filgrastim; lenograstim; pluripoietin
UniProt Protein Name
Granulocyte colony-stimulating factor
UniProt Synonym Protein Names
Pluripoietin; INN: Filgrastim; INN: Lenograstim
UniProt Synonym Gene Names
UniProt Entry Name
CSF3_HUMAN
NCBI Summary for GCSF
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
UniProt Comments for GCSF
G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Cell cycle regulation; Secreted, signal peptide; Cytokine
Chromosomal Location of Human Ortholog: 17q11.2-q12
Cellular Component: extracellular space
Molecular Function: enzyme binding; growth factor activity; cytokine activity; granulocyte colony-stimulating factor receptor binding
Biological Process: positive regulation of protein binding; positive regulation of myeloid cell differentiation; granulocyte differentiation; cytokine and chemokine mediated signaling pathway; multicellular organismal development; positive regulation of peptidyl-serine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of actin filament polymerization; positive regulation of cell proliferation; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; immune response
Research Articles on GCSF
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Products associated with GCSF elisa kit
Pathways associated with GCSF elisa kit
Diseases associated with GCSF elisa kit
Organs/Tissues associated with GCSF elisa kit
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