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Hepc elisa kit :: Guinea Pig Hepcidin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS723291
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Hepcidin, ELISA Kit

 Also Known As   

Guinea pig Hepcidin ELISA Kit

 Product Gene Name   

Hepc elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    gene 613313
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 Species Reactivity    Guinea Pig
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of Hepc elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Hepc purchase    MBS723291 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hepcidin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Hepc. The ELISA analytical biochemical technique of the MBS723291 kit is based on Hepc antibody-Hepc antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Hepc antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Hepc. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for Hepc elisa kit    Cardiovascular
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 Typical Testing Data/Standard Curve (for reference only) of Hepc elisa kit    Hepc elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS723291
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NCBI/Uniprot data below describe general gene information for Hepc. It may not necessarily be applicable to this product.
 NCBI GI #    10863973
 NCBI GeneID    57817
 NCBI Accession #    NP_066998.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021175.2 [Other Products]
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 UniProt Secondary Accession #    Q1HE14; Q9BY68 [Other Products]
 UniProt Related Accession #    P81172 [Other Products]
 Molecular Weight    9,408 Da
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 NCBI Official Full Name    hepcidin preproprotein
 NCBI Official Synonym Full Names    hepcidin antimicrobial peptide
 NCBI Official Symbol    HAMP [Similar Products]
 NCBI Official Synonym Symbols   
HEPC; PLTR; HFE2B; LEAP1
[Similar Products]
 NCBI Protein Information    hepcidin; putative liver tumor regressor; liver-expressed antimicrobial peptide 1
 UniProt Protein Name    Hepcidin
 UniProt Synonym Protein Names   
Liver-expressed antimicrobial peptide 1; LEAP-1; Putative liver tumor regressor; PLTR
 Protein Family    Hepcidin
 UniProt Gene Name    HAMP [Similar Products]
 UniProt Synonym Gene Names    HEPC; LEAP1; UNQ487/PRO1003; LEAP-1; PLTR; Hepc25; Hepc20 [Similar Products]
 UniProt Entry Name    HEPC_HUMAN
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 NCBI Summary for Hepc    The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008]
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 UniProt Comments for Hepc    HAMP: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. Defects in HAMP are the cause of hemochromatosis type 2B (HFE2B); also known as juvenile hemochromatosis (JH). HFE2B is a disorder of iron metabolism with excess deposition of iron in the tissues, bronze skin pigmentation, hepatic cirrhosis, arthropathy and diabetes. The most common symptoms of hemochromatosis type 2 at presentation are hypogonadism and cardiomyopathy. Belongs to the hepcidin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: apical cortex; extracellular region

Molecular Function: hormone activity

Biological Process: cellular iron ion homeostasis; killing of cells of another organism; defense response to bacterium; immune response; defense response to fungus

Disease: Hemochromatosis, Type 2b
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 Research Articles on Hepc    1. Irin status, erythropoietic drive, inflammation, and malaria season combine to control dynamic fluctuations of hepcidin in African children.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Hepc elisa kitPathways associated with Hepc elisa kit
 Reference Product  PubMed Publications
 TFR2 elisa kit  >131 publications with Hepc and TFR2
 HFE2 elisa kit  >114 publications with Hepc and HFE2
 STAT3 elisa kit  >54 publications with Hepc and STAT3
 TMPRSS6 elisa kit  >47 publications with Hepc and TMPRSS6
 GDF15 elisa kit  >44 publications with Hepc and GDF15
 SLC40A1 elisa kit  >42 publications with Hepc and SLC40A1
 IL6 elisa kit  >33 publications with Hepc and IL6
 SLC11A2 elisa kit  >5 publications with Hepc and SLC11A2
 Products by Pathway  Pathway Diagram
 Iron Metabolism In Placenta Pathway antibodies  Iron Metabolism In Placenta Pathway Diagram
Diseases associated with Hepc elisa kitOrgans/Tissues associated with Hepc elisa kit
 Disease Name  Pubmed Publications
 Anemia Antibodies  >672 publications with Hepc and Anemia
 Iron Overload Antibodies  >633 publications with Hepc and Iron Overload
 Inflammation Antibodies  >495 publications with Hepc and Inflammation
 Hemochromatosis Antibodies  >427 publications with Hepc and Hemochromatosis
 Liver Diseases Antibodies  >249 publications with Hepc and Liver Diseases
 Kidney Diseases Antibodies  >139 publications with Hepc and Kidney Diseases
 Disease Models, Animal Antibodies  >115 publications with Hepc and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >78 publications with Hepc and Cardiovascular Diseases
 Necrosis Antibodies  >70 publications with Hepc and Necrosis
 beta-Thalassemia Antibodies  >63 publications with Hepc and beta-Thalassemia
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >759 publications with Hepc and Liver
 Spleen Antibodies  >109 publications with Hepc and Spleen
 Brain Antibodies  >35 publications with Hepc and Brain
 Eye Antibodies  >19 publications with Hepc and Eye
 Lung Antibodies  >17 publications with Hepc and Lung
 Placenta Antibodies  >15 publications with Hepc and Placenta
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