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OSC elisa kit :: Guinea Pig Oxidosqualene Cyclase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS729667 OSC elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Oxidosqualene Cyclase (OSC), ELISA Kit

 Also Known As   

Guinea pig Oxidosqualene Cyclase ELISA Kit

 Product Gene Name   

OSC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Guinea Pig
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    5.0-100ng/mL
 Sensitivity    1.0ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of OSC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for OSC purchase    MBS729667 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Oxidosqualene Cyclase (OSC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 5.0-100ng/mL in biological research samples containing OSC, with an estimated sensitivity of 1.0ng/mL. The ELISA analytical biochemical technique of the MBS729667 kit is based on OSC antibody-OSC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OSC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OSC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for OSC. It may not necessarily be applicable to this product.
 NCBI GI #    1098635
 NCBI GeneID    81681
 NCBI Accession #    AAA91023.1 [Other Products]
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 UniProt Secondary Accession #    Q62811 [Other Products]
 UniProt Related Accession #    P48450 [Other Products]
 Molecular Weight    83,301 Da
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 NCBI Official Full Name    oxidosqualene cyclase
 NCBI Official Synonym Full Names    lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
 NCBI Official Symbol    Lss [Similar Products]
 NCBI Protein Information    lanosterol synthase; OSC; oxidosqualene--lanosterol cyclase; 2,3-epoxysqualene--lanosterol cyclase; 2,3-oxidosqualene: lanosterol cyclase
 UniProt Protein Name    Lanosterol synthase
 UniProt Synonym Protein Names   
2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; OSC
 UniProt Gene Name    Lss [Similar Products]
 UniProt Synonym Gene Names    Osc; OSC [Similar Products]
 UniProt Entry Name    ERG7_RAT
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 NCBI Summary for OSC    enzyme that catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol [RGD, Feb 2006]
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 UniProt Comments for OSC    LSS: Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Belongs to the terpene cyclase/mutase family.

Protein type: Isomerase; EC 5.4.99.7; Lipid Metabolism - steroid biosynthesis

Cellular Component: endoplasmic reticulum membrane; membrane; intracellular membrane-bound organelle; lipid particle

Molecular Function: lanosterol synthase activity; intramolecular transferase activity

Biological Process: metabolic process; sterol metabolic process; cholesterol biosynthetic process
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 Research Articles on OSC    1. Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OSC elisa kitPathways associated with OSC elisa kit
 Reference Product  PubMed Publications
 Fdft1 elisa kit  >6 publications with OSC and Fdft1
 Sqle elisa kit  >4 publications with OSC and Sqle
 Mvd elisa kit  >2 publications with OSC and Mvd
 Srebf1 elisa kit  >2 publications with OSC and Srebf1
 Hsd17b7 elisa kit  >2 publications with OSC and Hsd17b7
 Dhcr24 elisa kit  >2 publications with OSC and Dhcr24
 Cyp51 elisa kit  >2 publications with OSC and Cyp51
 Sc4mol elisa kit  >1 publications with OSC and Sc4mol
 Srebf2 elisa kit  >1 publications with OSC and Srebf2
 Products by Pathway  Pathway Diagram
 Cholesterol Biosynthesis Pathway antibodies  Cholesterol Biosynthesis Pathway Diagram
 Cholesterol Biosynthesis, Squalene 2,3-epoxide => Cholesterol Pathway antibodies  Cholesterol Biosynthesis, Squalene 2,3-epoxide => Cholesterol Pathway Diagram
 Cholesterol Biosynthesis, Squalene 2,3-epoxide => Cholesterol Pathway antibodies  Cholesterol Biosynthesis, Squalene 2,3-epoxide => Cholesterol Pathway Diagram
 Cholesterol Metabolism Pathway antibodies  Cholesterol Metabolism Pathway Diagram
 Cholesterol Metabolism Pathway antibodies  Cholesterol Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
Diseases associated with OSC elisa kitOrgans/Tissues associated with OSC elisa kit
 Disease Name  Pubmed Publications
 Pain Antibodies  >218 publications with OSC and Pain
 Nervous System Diseases Antibodies  >155 publications with OSC and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >77 publications with OSC and Cardiovascular Diseases
 Mental Disorders Antibodies  >31 publications with OSC and Mental Disorders
 Brain Diseases Antibodies  >29 publications with OSC and Brain Diseases
 Inflammation Antibodies  >22 publications with OSC and Inflammation
 Hypertrophy Antibodies  >20 publications with OSC and Hypertrophy
 Liver Diseases Antibodies  >18 publications with OSC and Liver Diseases
 Hypertension Antibodies  >18 publications with OSC and Hypertension
 Heart Diseases Antibodies  >17 publications with OSC and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >70 publications with OSC and Nerve
 Liver Antibodies  >58 publications with OSC and Liver
 Lung Antibodies  >47 publications with OSC and Lung
 Kidney Antibodies  >42 publications with OSC and Kidney
 Brain Antibodies  >37 publications with OSC and Brain
 Spleen Antibodies  >19 publications with OSC and Spleen
 Colon Antibodies  >16 publications with OSC and Colon
 Prostate Antibodies  >13 publications with OSC and Prostate
 Ovary Antibodies  >9 publications with OSC and Ovary
 Eye Antibodies  >8 publications with OSC and Eye
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