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pMAPT/pTAU elisa kit :: Guinea Pig phosphorylated microtubule Associated protein tau ELISA Kit

Scan QR to view Datasheet Catalog #    MBS721180 pMAPT/pTAU elisa kit
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

phosphorylated microtubule Associated protein tau (pMAPT/pTAU), ELISA Kit

 Also Known As   

Guinea pig phosphorylated microtubule Associated protein tau ELISA Kit

 Product Gene Name   

pMAPT/pTAU elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Guinea Pig
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of pMAPT/pTAU elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for pMAPT/pTAU purchase    MBS721180 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the phosphorylated microtubule Associated protein tau (pMAPT/pTAU) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing pMAPT/pTAU. The ELISA analytical biochemical technique of the MBS721180 kit is based on pMAPT/pTAU antibody-pMAPT/pTAU antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect pMAPT/pTAU antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, pMAPT/pTAU. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for pMAPT/pTAU. It may not necessarily be applicable to this product.
 NCBI GI #    672069501
 NCBI GeneID    29477
 NCBI Accession #    XP_008766504.1 [Other Products]
 NCBI GenBank Nucleotide #    XM_008768282.1 [Other Products]
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 UniProt Secondary Accession #    Q63567; Q63677; Q9QW06 [Other Products]
 UniProt Related Accession #    P19332 [Other Products]
 Molecular Weight    81,185 Da
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 NCBI Official Full Name    microtubule-associated protein tau isoform X14
 NCBI Official Synonym Full Names    microtubule-associated protein tau
 NCBI Official Symbol    Mapt [Similar Products]
 NCBI Official Synonym Symbols   
pTau; Mtapt; RNPTAU
[Similar Products]
 NCBI Protein Information    microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; Tau microtubule-associated protein
 UniProt Protein Name    Microtubule-associated protein tau
 UniProt Synonym Protein Names   
Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
 UniProt Gene Name    Mapt [Similar Products]
 UniProt Synonym Gene Names    Mtapt; Tau; PHF-tau [Similar Products]
 UniProt Entry Name    TAU_RAT
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 NCBI Summary for pMAPT/pTAU    a microtubule-associated protein; expression is found specifically in neurons [RGD, Feb 2006]
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 UniProt Comments for pMAPT/pTAU    Tau: a microtubule-associated protein that regulates microtubule assembly and stability. Apparently involved in the establishment and maintenance of neuronal polarity. Mutations can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. Nine differentially spliced isoforms have been described. The short isoforms allow plasticity of the cytoskeleton, whereas the longer isoforms may preferentially play a role in its stabilization.

Protein type: Cytoskeletal

Cellular Component: microtubule; neuron projection; cell; postsynaptic density; cytosol; microtubule cytoskeleton; growth cone; axon; cytoplasm; tubulin complex; plasma membrane; axoneme; intracellular; nucleus

Molecular Function: protein domain specific binding; protein binding; enzyme binding; protein phosphatase 2A binding; microtubule binding; protein complex binding; apolipoprotein binding; protein kinase binding; SH3 domain binding

Biological Process: axon extension; apoptosis; positive regulation of microtubule polymerization; positive regulation of axon extension; axon cargo transport; neuron migration; female pregnancy; microtubule cytoskeleton organization and biogenesis; adult walking behavior; microtubule-based process; mitochondrion transport along microtubule; neuron differentiation; response to organic substance; axonogenesis; negative regulation of intracellular transport; regulation of autophagy; brain development; induction of apoptosis by oxidative stress; response to nutrient
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 Research Articles on pMAPT/pTAU    1. Hyperphosphorylation of tau protein in hippocampus of insulin-resistant rats is associated with cognitive impairment.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with pMAPT/pTAU elisa kitOrgans/Tissues associated with pMAPT/pTAU elisa kit
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies  Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >701 publications with pMAPT/pTAU and Brain
 Nerve Antibodies  >228 publications with pMAPT/pTAU and Nerve
 Eye Antibodies  >14 publications with pMAPT/pTAU and Eye
 Embryonic Tissue Antibodies  >10 publications with pMAPT/pTAU and Embryonic Tissue
 Heart Antibodies  >8 publications with pMAPT/pTAU and Heart
 Kidney Antibodies  >6 publications with pMAPT/pTAU and Kidney
 Prostate Antibodies  >3 publications with pMAPT/pTAU and Prostate
 Dorsal Root Ganglion Antibodies  >3 publications with pMAPT/pTAU and Dorsal Root Ganglion
 Lung Antibodies  >2 publications with pMAPT/pTAU and Lung
 Testis Antibodies  >1 publications with pMAPT/pTAU and Testis
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