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ADAM11 elisa kit :: Hamster A Disintegrin and Metalloprotease 11 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS074721 ADAM11 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin and Metalloprotease 11 (ADAM11), ELISA Kit

 Also Known As   

Hamster A Disintegrin and Metalloprotease 11 ELISA Kit

 Product Gene Name   

ADAM11 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    605007
 3D Structure    ModBase 3D Structure for Q9UNA0
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 Species Reactivity    Hamster
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of ADAM11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADAM11 purchase    MBS074721 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 11 (ADAM11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADAM11. The ELISA analytical biochemical technique of the MBS074721 kit is based on ADAM11 antibody-ADAM11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAM11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAM11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ADAM11. It may not necessarily be applicable to this product.
 NCBI GI #    317373326
 NCBI GeneID    11096
 NCBI Accession #    Q9UNA0.2 [Other Products]
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 UniProt Primary Accession #    Q9UNA0 [Other Products]
 UniProt Secondary Accession #    Q52LV4; Q9UKP2 [Other Products]
 UniProt Related Accession #    Q9UNA0 [Other Products]
 Molecular Weight    101,718 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 5
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif, 5
 NCBI Official Symbol    ADAMTS5 [Similar Products]
 NCBI Official Synonym Symbols   
ADMP-2; ADAM-TS5; ADAMTS-5; ADAMTS11; ADAM-TS 5; ADAMTS-11; ADAM-TS 11
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 5; aggrecanase-2; a disintegrin and metalloproteinase with thrombospondin motifs 11; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 5
 UniProt Synonym Protein Names   
A disintegrin and metalloproteinase with thrombospondin motifs 11; ADAM-TS 11; ADAMTS-11; ADMP-2; Aggrecanase-2
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    ADAMTS5 [Similar Products]
 UniProt Synonym Gene Names    ADAMTS11; ADMP2; ADAM-TS 5; ADAM-TS5; ADAMTS-5; ADAM-TS 11; ADAMTS-11 [Similar Products]
 UniProt Entry Name    ATS5_HUMAN
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 NCBI Summary for ADAM11    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAM11    ADAMTS5: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.

Protein type: EC 3.4.24.-; Motility/polarity/chemotaxis; Protease; Secreted, signal peptide; Secreted; Extracellular matrix

Chromosomal Location of Human Ortholog: 21q21.3

Cellular Component: proteinaceous extracellular matrix; endoplasmic reticulum lumen; extracellular region

Molecular Function: integrin binding; protein binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity

Biological Process: protein amino acid O-linked glycosylation; extracellular matrix disassembly; extracellular matrix organization and biogenesis; cellular protein metabolic process; defense response to bacterium; post-translational protein modification; proteolysis
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 Research Articles on ADAM11    1. psiepsilonRACK induced upregulation of hsa-miR-377 expression, coupled to decreases in ADAMTS5 and cleaved aggrecan
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADAM11 elisa kitPathways associated with ADAM11 elisa kit
 Reference Product  PubMed Publications
 MMP13 elisa kit  >37 publications with ADAM11 and MMP13
 MMP3 elisa kit  >18 publications with ADAM11 and MMP3
 TIMP3 elisa kit  >13 publications with ADAM11 and TIMP3
 ACAN elisa kit  >13 publications with ADAM11 and ACAN
 FGF2 elisa kit  >9 publications with ADAM11 and FGF2
 RUNX2 elisa kit  >9 publications with ADAM11 and RUNX2
 FURIN elisa kit  >4 publications with ADAM11 and FURIN
 SDC4 elisa kit  >4 publications with ADAM11 and SDC4
 Products by Pathway  Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-glycosylation Of TSR Domain-containing Proteins Pathway antibodies  O-glycosylation Of TSR Domain-containing Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
Diseases associated with ADAM11 elisa kitOrgans/Tissues associated with ADAM11 elisa kit
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >39 publications with ADAM11 and Disease Models, Animal
 Necrosis Antibodies  >35 publications with ADAM11 and Necrosis
 Inflammation Antibodies  >25 publications with ADAM11 and Inflammation
 Neoplasms Antibodies  >16 publications with ADAM11 and Neoplasms
 Nervous System Diseases Antibodies  >12 publications with ADAM11 and Nervous System Diseases
 Hypertrophy Antibodies  >8 publications with ADAM11 and Hypertrophy
 Central Nervous System Diseases Antibodies  >5 publications with ADAM11 and Central Nervous System Diseases
 Fibrosis Antibodies  >4 publications with ADAM11 and Fibrosis
 Brain Diseases Antibodies  >4 publications with ADAM11 and Brain Diseases
 Heart Diseases Antibodies  >3 publications with ADAM11 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >52 publications with ADAM11 and Connective Tissue
 Muscle Antibodies  >14 publications with ADAM11 and Muscle
 Embryonic Tissue Antibodies  >12 publications with ADAM11 and Embryonic Tissue
 Brain Antibodies  >11 publications with ADAM11 and Brain
 Skin Antibodies  >6 publications with ADAM11 and Skin
 Liver Antibodies  >4 publications with ADAM11 and Liver
 Heart Antibodies  >4 publications with ADAM11 and Heart
 Eye Antibodies  >4 publications with ADAM11 and Eye
 Lung Antibodies  >2 publications with ADAM11 and Lung
 Ovary Antibodies  >2 publications with ADAM11 and Ovary
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