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AT2R1 elisa kit :: Hamster Angiotensin 2 Receptor 1 Antibody ELISA Kit

Scan QR to view Datasheet Catalog #    MBS018101 AT2R1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Angiotensin 2 Receptor 1 Antibody (AT2R1), ELISA Kit

 Also Known As   

Hamster Angiotensin 2 Receptor 1 Antibody ELISA Kit

 Product Gene Name   

AT2R1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    151530
 3D Structure    ModBase 3D Structure for P15144
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 Species Reactivity    Hamster
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AT2R1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AT2R1 purchase    MBS018101 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Angiotensin 2 Receptor 1 Antibody (AT2R1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AT2R1. The ELISA analytical biochemical technique of the MBS018101 kit is based on AT2R1 antibody-AT2R1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AT2R1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AT2R1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AT2R1. It may not necessarily be applicable to this product.
 NCBI GI #    157266300
 NCBI GeneID    290
 NCBI Accession #    NP_001141.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001150.2 [Other Products]
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 UniProt Primary Accession #    P15144 [Other Products]
 UniProt Secondary Accession #    Q16728; Q6GT90; Q8IUK3; Q8IVH3; Q9UCE0 [Other Products]
 UniProt Related Accession #    P15144 [Other Products]
 Molecular Weight    109,540 Da
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 NCBI Official Full Name    aminopeptidase N
 NCBI Official Synonym Full Names    alanyl (membrane) aminopeptidase
 NCBI Official Symbol    ANPEP [Similar Products]
 NCBI Official Synonym Symbols   
APN; CD13; LAP1; P150; PEPN; GP150
[Similar Products]
 NCBI Protein Information    aminopeptidase N; AP-M; AP-N; hAPN; aminopeptidase M; alanyl aminopeptidase; microsomal aminopeptidase; myeloid plasma membrane glycoprotein CD13
 UniProt Protein Name    Aminopeptidase N
 UniProt Synonym Protein Names   
Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150
 UniProt Gene Name    ANPEP [Similar Products]
 UniProt Synonym Gene Names    APN; CD13; PEPN; AP-N; hAPN; AP-M [Similar Products]
 UniProt Entry Name    AMPN_HUMAN
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 NCBI Summary for AT2R1    Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AT2R1    CD13: Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types including small intestinal and tubular epithelial cells, macrophages, granulocytes and synaptic membranes from the CNS. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection. Belongs to the peptidase M1 family.

Protein type: Protease; Other Amino Acids Metabolism - glutathione; EC 3.4.11.2; Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q25-q26

Cellular Component: extracellular space; lysosomal membrane; integral to plasma membrane; ER-Golgi intermediate compartment; cytosol; external side of plasma membrane

Molecular Function: viral receptor activity; zinc ion binding; metallopeptidase activity; receptor activity; aminopeptidase activity

Biological Process: entry of virus into host cell; cellular protein metabolic process; angiogenesis; angiotensin maturation; proteolysis; cell differentiation
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 Research Articles on AT2R1    1. CD13 participates in phagocytic processes in dendritic cells and macrophages.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AT2R1 elisa kitPathways associated with AT2R1 elisa kit
 Reference Product  PubMed Publications
 ENPEP elisa kit  >1 publications with AT2R1 and ENPEP
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies  Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
Diseases associated with AT2R1 elisa kitOrgans/Tissues associated with AT2R1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with AT2R1 and Neoplasms
 Carcinoma Antibodies  >4 publications with AT2R1 and Carcinoma
 Adenocarcinoma Antibodies  >3 publications with AT2R1 and Adenocarcinoma
 Hypertension Antibodies  >3 publications with AT2R1 and Hypertension
 Cardiovascular Diseases Antibodies  >2 publications with AT2R1 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >2 publications with AT2R1 and Vascular Diseases
 Immune System Diseases Antibodies  >2 publications with AT2R1 and Immune System Diseases
 Nervous System Diseases Antibodies  >1 publications with AT2R1 and Nervous System Diseases
 Fibrosis Antibodies  >1 publications with AT2R1 and Fibrosis
 Breast Neoplasms Antibodies  >1 publications with AT2R1 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with AT2R1 and Blood
 Prostate Antibodies  >3 publications with AT2R1 and Prostate
 Embryonic Tissue Antibodies  >3 publications with AT2R1 and Embryonic Tissue
 Kidney Antibodies  >2 publications with AT2R1 and Kidney
 Uterus Antibodies  >2 publications with AT2R1 and Uterus
 Connective Tissue Antibodies  >2 publications with AT2R1 and Connective Tissue
 Pancreas Antibodies  >2 publications with AT2R1 and Pancreas
 Vascular Antibodies  >2 publications with AT2R1 and Vascular
 Lymph Node Antibodies  >2 publications with AT2R1 and Lymph Node
 Lung Antibodies  >1 publications with AT2R1 and Lung
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