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CLEC3B elisa kit :: Hamster C-Type Lectin Domain Family 3, Member B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS074414 CLEC3B elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-Type Lectin Domain Family 3, Member B (CLEC3B), ELISA Kit

 Also Known As   

Hamster C-Type Lectin Domain Family 3, Member B ELISA Kit

 Product Gene Name   

CLEC3B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    606264
 3D Structure    ModBase 3D Structure for Q9BXN2
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 Species Reactivity    Hamster
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CLEC3B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CLEC3B purchase    MBS074414 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-Type Lectin Domain Family 3, Member B (CLEC3B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CLEC3B. The ELISA analytical biochemical technique of the MBS074414 kit is based on CLEC3B antibody-CLEC3B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CLEC3B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CLEC3B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CLEC3B. It may not necessarily be applicable to this product.
 NCBI GI #    13384604
 NCBI GeneID    64581
 NCBI Accession #    NP_072092.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022570.4 [Other Products]
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 UniProt Primary Accession #    Q9BXN2 [Other Products]
 UniProt Secondary Accession #    Q6IPS7; Q96D32; Q96DR9; Q96LD3; Q96PA4; Q96PA5; Q96PA6; B2R861; B7Z494; B7Z5A9; B7Z5B9 [Other Products]
 UniProt Related Accession #    Q9BXN2 [Other Products]
 Molecular Weight    27,627 Da
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 NCBI Official Full Name    C-type lectin domain family 7 member A isoform b
 NCBI Official Synonym Full Names    C-type lectin domain family 7, member A
 NCBI Official Symbol    CLEC7A [Similar Products]
 NCBI Official Synonym Symbols   
BGR; CANDF4; DECTIN1; CLECSF12
[Similar Products]
 NCBI Protein Information    C-type lectin domain family 7 member A; dectin-1; beta-glucan receptor; lectin-like receptor 1; DC-associated C-type lectin 1; C-type lectin superfamily member 12; dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12
 UniProt Protein Name    C-type lectin domain family 7 member A
 UniProt Synonym Protein Names   
Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1
 Protein Family    Tetranectin
 UniProt Gene Name    CLEC7A [Similar Products]
 UniProt Synonym Gene Names    BGR; CLECSF12; DECTIN1; DC-associated C-type lectin 1; Dectin-1 [Similar Products]
 UniProt Entry Name    CLC7A_HUMAN
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 NCBI Summary for CLEC3B    This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CLEC3B    dectin-1: Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation. Up-regulated during differentiation from monocytes into dendritic cells. Isoform 5 interacts with RANBP9. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.2

Cellular Component: cytoplasm; plasma membrane; integral to membrane

Molecular Function: metal ion binding; MHC protein binding; carbohydrate binding; pattern recognition receptor activity

Biological Process: T cell activation; innate immune response; carbohydrate mediated signaling; cell recognition; phagocytosis, recognition; pattern recognition receptor signaling pathway; inflammatory response; defense response to protozoan

Disease: Candidiasis, Familial, 4; Aspergillosis, Susceptibility To
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 Research Articles on CLEC3B    1. The unconventional protein secretion triggered by the dectin-1 pathway is dependent on inflammasome activity and an active autophagic process.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CLEC3B elisa kitDiseases associated with CLEC3B elisa kit
 Products by Pathway  Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >11 publications with CLEC3B and Inflammation
 Necrosis Antibodies  >5 publications with CLEC3B and Necrosis
 Lung Diseases Antibodies  >2 publications with CLEC3B and Lung Diseases
 Colitis Antibodies  >2 publications with CLEC3B and Colitis
 Atherosclerosis Antibodies  >1 publications with CLEC3B and Atherosclerosis
 Liver Cirrhosis Antibodies  >1 publications with CLEC3B and Liver Cirrhosis
 Non-alcoholic Fatty Liver Disease Antibodies  >1 publications with CLEC3B and Non-alcoholic Fatty Liver Disease
 Fatty Liver Antibodies  >1 publications with CLEC3B and Fatty Liver
 Neoplasms Antibodies  >1 publications with CLEC3B and Neoplasms
 Liver Diseases Antibodies  >1 publications with CLEC3B and Liver Diseases
Organs/Tissues associated with CLEC3B elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >20 publications with CLEC3B and Blood
 Lung Antibodies  >6 publications with CLEC3B and Lung
 Bone Marrow Antibodies  >3 publications with CLEC3B and Bone Marrow
 Intestine Antibodies  >2 publications with CLEC3B and Intestine
 Vascular Antibodies  >1 publications with CLEC3B and Vascular
 Spleen Antibodies  >1 publications with CLEC3B and Spleen
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