Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow DCX rightarrow Hamster DCX  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • LHR2A Antibody
 • PRPF39 Antibody
 • MRPL4 Antibody
 • Specificity Protein 1 (SP1) ELISA Kit
 • Contactin 2 (CNTN2) ELISA Kit
 • Perilipin 1 (PLIN1) ELISA Kit
 • Cyclophilin A (CYPA) ELISA Kit
 • P 38 Mitogen-Activated Protein Kinase (P38MAPK) ELISA Kit
 • Immune Ribonucleic Acid-Immune Rna (IRNA) ELISA Kit
 • Cathepsin Antibodies (CTS) ELISA Kit
 • Metallothionein (MT) ELISA Kit
 • Fibrillin 2 (FBN2) ELISA Kit
 • Elastase 4 (ELA4) ELISA Kit
 • Ornithine Carbamoyl Transferase (OCT) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

DCX elisa kit :: Hamster Doublecortin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS013331 DCX elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Doublecortin (DCX), ELISA Kit

 Also Known As   

Hamster Doublecortin ELISA Kit

 Product Gene Name   

DCX elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: X; NC_000023.10 (110537007..110655460, complement). Location: Xq22.3-q23
 OMIM    300067
 3D Structure    ModBase 3D Structure for O43602
Section Bar
 Species Reactivity    Hamster
Section Bar
Section Bar
 Assay Type    Sandwich
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DCX elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DCX purchase    MBS013331 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Doublecortin (DCX) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DCX. The ELISA analytical biochemical technique of the MBS013331 kit is based on DCX antibody-DCX antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DCX antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DCX. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for DCX. It may not necessarily be applicable to this product.
 NCBI GI #    3114810
 NCBI GeneID    1641
 NCBI Accession #    CAA06617.1 [Other Products]
Section Bar
 UniProt Primary Accession #    O43602 [Other Products]
 UniProt Secondary Accession #    O43911; Q5JYZ5; A6NFY6; A9Z1V8; D3DUY8; D3DUY9; D3DUZ0 [Other Products]
 UniProt Related Accession #    O43602 [Other Products]
 Molecular Weight    49,318 Da
Table BarTOPTable Bar
 NCBI Official Full Name    doublecortin
 NCBI Official Synonym Full Names    doublecortin
 NCBI Official Symbol    DCX [Similar Products]
 NCBI Official Synonym Symbols   
DC; DBCN; LISX; SCLH; XLIS
[Similar Products]
 NCBI Protein Information    neuronal migration protein doublecortin; lis-X; doublin; doublecortex; lissencephalin-X
 UniProt Protein Name    Neuronal migration protein doublecortin
 UniProt Synonym Protein Names   
Doublin; Lissencephalin-X
 Protein Family    Doublecortin domain-containing protein
 UniProt Gene Name    DCX [Similar Products]
 UniProt Synonym Gene Names    DBCN; LISX; Lis-X [Similar Products]
 UniProt Entry Name    DCX_HUMAN
Section Bar
 NCBI Summary for DCX    This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Section Bar
 UniProt Comments for DCX    Doublecortin: Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration. Interacts with tubulin. Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. In the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xq22.3-q23

Cellular Component: microtubule; neuron projection; microtubule associated complex; cytoskeleton; cytosol

Molecular Function: protein binding; microtubule binding; protein kinase binding

Biological Process: nervous system development; axon guidance; central nervous system development; axon extension; dendrite morphogenesis; neuron migration; central nervous system projection neuron axonogenesis; brain development

Disease: Lissencephaly, X-linked, 1
Table BarTOPTable Bar
 Research Articles on DCX    1. This finding points to the possible implication of mosaic deletions in the DCX gene in unexplained forms of subcortical band heterotopia (SBH) and may allow for detection of SBH prenatally.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with DCX elisa kitPathways associated with DCX elisa kit
 Reference Product  PubMed Publications
 GFAP elisa kit  >82 publications with DCX and GFAP
 PAFAH1B1 elisa kit  >48 publications with DCX and PAFAH1B1
 CDK5 elisa kit  >8 publications with DCX and CDK5
 MAPK8 elisa kit  >2 publications with DCX and MAPK8
 NES elisa kit  >1 publications with DCX and NES
 RBFOX3 elisa kit  >1 publications with DCX and RBFOX3
 MARK2 elisa kit  >1 publications with DCX and MARK2
 NFASC elisa kit  >1 publications with DCX and NFASC
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 L1CAM Interactions Pathway antibodies  L1CAM Interactions Pathway Diagram
 Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway antibodies  Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway Diagram
 Neurofascin Interactions Pathway antibodies  Neurofascin Interactions Pathway Diagram
Diseases associated with DCX elisa kitOrgans/Tissues associated with DCX elisa kit
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >212 publications with DCX and Brain Diseases
 Cardiovascular Diseases Antibodies  >83 publications with DCX and Cardiovascular Diseases
 Neoplasms Antibodies  >40 publications with DCX and Neoplasms
 Movement Disorders Antibodies  >24 publications with DCX and Movement Disorders
 Neurobehavioral Manifestations Antibodies  >19 publications with DCX and Neurobehavioral Manifestations
 Drug Toxicity Antibodies  >17 publications with DCX and Drug Toxicity
 LISSENCEPHALY, X-LINKED, 1 Antibodies  >16 publications with DCX and LISSENCEPHALY, X-LINKED, 1
 Brain Injuries Antibodies  >15 publications with DCX and Brain Injuries
 Inflammation Antibodies  >15 publications with DCX and Inflammation
 Cognition Disorders Antibodies  >13 publications with DCX and Cognition Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >624 publications with DCX and Brain
 Vascular Antibodies  >29 publications with DCX and Vascular
 Embryonic Tissue Antibodies  >24 publications with DCX and Embryonic Tissue
 Eye Antibodies  >15 publications with DCX and Eye
 Muscle Antibodies  >10 publications with DCX and Muscle
 Mouth Antibodies  >3 publications with DCX and Mouth
 Testis Antibodies  >2 publications with DCX and Testis
 Lung Antibodies  >2 publications with DCX and Lung
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions