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FOXP3 elisa kit :: Hamster Forkhead Box Protein P3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS011360 FOXP3 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Forkhead Box Protein P3 (FOXP3), ELISA Kit

 Also Known As   

Hamster Forkhead Box Protein P3 ELISA Kit

 Product Gene Name   

FOXP3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: X; NC_000023.10 (49106897..49121288, complement). Location: Xp11.23
 OMIM    300292
 3D Structure    ModBase 3D Structure for Q9BZS1
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 Species Reactivity    Hamster
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FOXP3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FOXP3 purchase    MBS011360 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Forkhead Box Protein P3 (FOXP3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FOXP3. The ELISA analytical biochemical technique of the MBS011360 kit is based on FOXP3 antibody-FOXP3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FOXP3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FOXP3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FOXP3. It may not necessarily be applicable to this product.
 NCBI GI #    167466190
 NCBI GeneID    50943
 NCBI Accession #    NP_001107849.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001114377.1 [Other Products]
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 UniProt Primary Accession #    Q9BZS1 [Other Products]
 UniProt Secondary Accession #    O60827; Q14DD8; Q4ZH51; A5HJT1; B7ZLG0 [Other Products]
 UniProt Related Accession #    Q9BZS1 [Other Products]
 Molecular Weight    47,244 Da
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 NCBI Official Full Name    forkhead box protein P3 isoform b
 NCBI Official Synonym Full Names    forkhead box P3
 NCBI Official Symbol    FOXP3 [Similar Products]
 NCBI Official Synonym Symbols   
JM2; AIID; IPEX; PIDX; XPID; DIETER
[Similar Products]
 NCBI Protein Information    forkhead box protein P3; scurfin; FOXP3delta7; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; immune dysregulation, polyendocrinopathy, enteropathy, X-linked
 UniProt Protein Name    Forkhead box protein P3
 UniProt Synonym Protein Names   
Scurfin
 Protein Family    Forkhead box protein
 UniProt Gene Name    FOXP3 [Similar Products]
 UniProt Synonym Gene Names    IPEX [Similar Products]
 UniProt Entry Name    FOXP3_HUMAN
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 NCBI Summary for FOXP3    The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FOXP3    FOXP3: Probable transcription factor. Plays a critical role in the control of immune response. Interacts with IKZF3. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Transcription factor; DNA-binding; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: protein complex; cytoplasm; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; NF-kappaB binding; histone acetyltransferase binding; protein binding; NFAT protein binding; protein homodimerization activity; sequence-specific DNA binding; histone deacetylase binding; metal ion binding; transcription corepressor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; negative regulation of interleukin-4 production; T cell activation; negative regulation of interleukin-10 production; negative regulation of activated T cell proliferation; positive regulation of transcription, DNA-dependent; negative regulation of cytokine secretion; myeloid cell homeostasis; negative regulation of transcription from RNA polymerase II promoter; T cell receptor signaling pathway; negative regulation of interleukin-2 production; negative regulation of interferon-gamma biosynthetic process; negative regulation of histone acetylation; positive regulation of interleukin-4 production; negative regulation of cell proliferation; CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment; negative regulation of isotype switching to IgE isotypes; negative regulation of T cell proliferation; regulation of transcription, DNA-dependent; B cell homeostasis; negative regulation of interferon-gamma production; negative regulation of interleukin-6 production; T cell homeostasis; regulation of isotype switching to IgG isotypes; positive regulation of T cell anergy; tolerance induction to self antigen; positive regulation of transforming growth factor-beta1 production; negative regulation of chronic inflammatory response; negative regulation of histone deacetylation; negative regulation of transcription factor activity; T cell mediated immunity; response to virus; negative regulation of immune response; cytokine production; positive regulation of immature T cell proliferation in the thymus; negative regulation of tumor necrosis factor production; negative regulation of T cell cytokine production; positive regulation of peripheral T cell tolerance induction; chromatin remodeling; negative regulation of interleukin-17 production; inhibition of NF-kappaB transcription factor; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; regulation of T cell anergy; negative regulation of interleukin-2 biosynthetic process; negative regulation of interleukin-5 production; positive regulation of histone acetylation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; inhibition of CREB transcription factor; negative regulation of cytokine biosynthetic process

Disease: Diabetes Mellitus, Insulin-dependent; Immunodysregulation, Polyendocrinopathy, And Enteropathy, X-linked
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 Research Articles on FOXP3    1. Our study has failed to found any association between FOXP3 gene polymorphisms rs2280883, rs3761548 and rs3761549 with endometriosis in Chinese Han patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FOXP3 elisa kitPathways associated with FOXP3 elisa kit
 Reference Product  PubMed Publications
 CD4 elisa kit  >5911 publications with FOXP3 and CD4
 IL2RA elisa kit  >1550 publications with FOXP3 and IL2RA
 JUN elisa kit  >739 publications with FOXP3 and JUN
 CTLA4 elisa kit  >527 publications with FOXP3 and CTLA4
 IL17A elisa kit  >517 publications with FOXP3 and IL17A
 TGFB1 elisa kit  >304 publications with FOXP3 and TGFB1
 IL2 elisa kit  >70 publications with FOXP3 and IL2
 RUNX1 elisa kit  >19 publications with FOXP3 and RUNX1
 NFATC2 elisa kit  >13 publications with FOXP3 and NFATC2
 IL7R elisa kit  >3 publications with FOXP3 and IL7R
 Products by Pathway  Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 IL2 Signaling Events Mediated By STAT5 Pathway antibodies  IL2 Signaling Events Mediated By STAT5 Pathway Diagram
 Inflammatory Bowel Disease Pathway antibodies  Inflammatory Bowel Disease Pathway Diagram
Diseases associated with FOXP3 elisa kitOrgans/Tissues associated with FOXP3 elisa kit
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >1736 publications with FOXP3 and Autoimmune Diseases
 Inflammation Antibodies  >1476 publications with FOXP3 and Inflammation
 Neoplasms Antibodies  >1337 publications with FOXP3 and Neoplasms
 Disease Models, Animal Antibodies  >1110 publications with FOXP3 and Disease Models, Animal
 Necrosis Antibodies  >542 publications with FOXP3 and Necrosis
 Nervous System Diseases Antibodies  >501 publications with FOXP3 and Nervous System Diseases
 Liver Diseases Antibodies  >293 publications with FOXP3 and Liver Diseases
 Encephalomyelitis, Autoimmune, Experimental Antibodies  >287 publications with FOXP3 and Encephalomyelitis, Autoimmune, Experimental
 Diabetes Mellitus, Type 1 Antibodies  >278 publications with FOXP3 and Diabetes Mellitus, Type 1
 Neoplasms, Experimental Antibodies  >262 publications with FOXP3 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7119 publications with FOXP3 and Blood
 Lymph Node Antibodies  >890 publications with FOXP3 and Lymph Node
 Spleen Antibodies  >832 publications with FOXP3 and Spleen
 Thymus Antibodies  >628 publications with FOXP3 and Thymus
 Lung Antibodies  >486 publications with FOXP3 and Lung
 Eye Antibodies  >91 publications with FOXP3 and Eye
 Ascites Antibodies  >12 publications with FOXP3 and Ascites
 Trachea Antibodies  >6 publications with FOXP3 and Trachea
 Mammary Gland Antibodies  >2 publications with FOXP3 and Mammary Gland
 Uncharacterized Tissue Antibodies  >1 publications with FOXP3 and Uncharacterized Tissue
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