Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow HSPA1A rightarrow Hamster HSPA1A  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • NIPA (Phospho-Ser354) Antibody
 • ETV6 Antibody
 • Abnormal Prothrombin (APT) ELISA Kit
 • Alpha Synuclein (SNCA) ELISA Kit
 • Osteopontin (OPN) ELISA Kit
 • Platelet Derived Growth Factor Subunit A (PDGFA) ELISA Kit
 • Myeloperoxidase (MPO) ELISA Kit
 • Phosphorylated Acetyl-CoA Catboxylase (PACCASE) ELISA Kit
 • Semaphorin-4D (SEMA4D) ELISA Kit
 • Testosterone, Free (FT) ELISA Kit
 • Deoxyribonoucleic Protein Antibody (DNP-AB) ELISA Kit
 • Hydroxy-Pyridinium Crosslinks (OH-PYD) ELISA Kit
 • Monoamine Oxidase (MAO) ELISA Kit
 • Galectin 8 (GAL8) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

HSPA1A elisa kit :: Hamster Heat Shock 70Kda Protein 1A ELISA Kit

Scan QR to view Datasheet Catalog #    MBS012890 HSPA1A elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Heat Shock 70Kda Protein 1A (HSPA1A), ELISA Kit

 Also Known As   

Hamster Heat Shock 70Kda Protein 1A ELISA Kit

 Product Gene Name   

HSPA1A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 6; NC_000006.11 (31783291..31785719). Location: 6p21.3
 OMIM    140550
 3D Structure    ModBase 3D Structure for P08107
Section Bar
 Species Reactivity    Hamster
Section Bar
Section Bar
 Assay Type    Sandwich
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HSPA1A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HSPA1A purchase    MBS012890 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Heat Shock 70Kda Protein 1A (HSPA1A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HSPA1A. The ELISA analytical biochemical technique of the MBS012890 kit is based on HSPA1A antibody-HSPA1A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HSPA1A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HSPA1A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for HSPA1A. It may not necessarily be applicable to this product.
 NCBI GI #    194248072
 NCBI GeneID    3303
 NCBI Accession #    NP_005336.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005345.5 [Other Products]
Section Bar
 UniProt Primary Accession #    P08107 [Other Products]
 UniProt Secondary Accession #    P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0; B4E3B6 [Other Products]
 UniProt Related Accession #    P08107 [Other Products]
 Molecular Weight    70,052 Da
Table BarTOPTable Bar
 NCBI Official Full Name    heat shock 70 kDa protein 1A/1B
 NCBI Official Synonym Full Names    heat shock 70kDa protein 1A
 NCBI Official Symbol    HSPA1A [Similar Products]
 NCBI Official Synonym Symbols   
HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A
[Similar Products]
 NCBI Protein Information    heat shock 70 kDa protein 1A/1B; HSP70-1/HSP70-2; heat shock 70kD protein 1A; heat shock-induced protein; heat shock 70 kDa protein 1/2; dnaK-type molecular chaperone HSP70-1
 UniProt Protein Name    Heat shock 70 kDa protein 1A/1B
 UniProt Synonym Protein Names   
Heat shock 70 kDa protein 1/2
 Protein Family    Heat shock 70 kDa protein
 UniProt Gene Name    HSPA1A [Similar Products]
 UniProt Synonym Gene Names    HSPA1; HSP70-1/HSP70-2 [Similar Products]
 UniProt Entry Name    HSP71_HUMAN
Section Bar
 NCBI Summary for HSPA1A    This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for HSPA1A    HSP70: a critical chaperone protein that has a high affinity for unfolded polypeptide chains. It binds extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In cooperation with other chaperones, hsp70 stabilizes preexistent proteins against aggregation and mediates the folding of newly translated polypeptides in the cytosol as well as within organelles. Mitochondrial HSP70 is crucial to the import process: mutant forms of HSP70 fail to import precursor proteins. Is anti-apoptotic in sympathetic neurones and mediates this effect primarily by suppressing c-Jun transcriptional signalling. Interacts with tau protein and mediates proper folding of tau. Can promote the degradation of tau protein. Triptolide, a potential therapeutic agent for progression/metastasis of pancreatic cancer, causes pancreatic cancer cell death by induction of apoptosis, an effect mediated by the inhibition of HSP70.

Protein type: Heat shock protein; Motility/polarity/chemotaxis; Chaperone

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: signalosome; focal adhesion; mitochondrion; endoplasmic reticulum; inclusion body; cytosol; ribonucleoprotein complex; centriole; nucleoplasm; perinuclear region of cytoplasm; cytoplasm; nuclear speck; nucleus; vesicle; ubiquitin ligase complex

Molecular Function: viral receptor activity; protein binding; enzyme binding; G-protein-coupled receptor binding; heat shock protein binding; ubiquitin protein ligase binding; double-stranded RNA binding; ATPase activity; unfolded protein binding; protein N-terminus binding; ATPase activity, coupled; ATP binding

Biological Process: negative regulation of cell proliferation; entry of virus into host cell; protein stabilization; positive regulation of erythrocyte differentiation; mRNA catabolic process; gene expression; negative regulation of protein ubiquitination; protein refolding; negative regulation of cell growth; response to unfolded protein; negative regulation of apoptosis
Table BarTOPTable Bar
 Research Articles on HSPA1A    1. Mature wild-type CFTR protein is regulated by dexamethasone post transcription, involving cotranslational mechanisms with HSP90 and HSP70, which enhances maturation and expression of wild-type CFTR
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with HSPA1A elisa kitPathways associated with HSPA1A elisa kit
 Reference Product  PubMed Publications
 DNAJB1 elisa kit  >14 publications with HSPA1A and DNAJB1
 HSF1 elisa kit  >11 publications with HSPA1A and HSF1
 STIP1 elisa kit  >3 publications with HSPA1A and STIP1
 HSPBP1 elisa kit  >3 publications with HSPA1A and HSPBP1
 TP53 elisa kit  >2 publications with HSPA1A and TP53
 BAG3 elisa kit  >2 publications with HSPA1A and BAG3
 STUB1 elisa kit  >1 publications with HSPA1A and STUB1
 Products by Pathway  Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Apoptosis Modulation By HSP70 Pathway antibodies  Apoptosis Modulation By HSP70 Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
Diseases associated with HSPA1A elisa kitOrgans/Tissues associated with HSPA1A elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >31 publications with HSPA1A and Neoplasms
 Cardiovascular Diseases Antibodies  >21 publications with HSPA1A and Cardiovascular Diseases
 Inflammation Antibodies  >19 publications with HSPA1A and Inflammation
 Drug Toxicity Antibodies  >15 publications with HSPA1A and Drug Toxicity
 Nervous System Diseases Antibodies  >12 publications with HSPA1A and Nervous System Diseases
 Liver Diseases Antibodies  >9 publications with HSPA1A and Liver Diseases
 Necrosis Antibodies  >8 publications with HSPA1A and Necrosis
 Brain Diseases Antibodies  >8 publications with HSPA1A and Brain Diseases
 Heart Diseases Antibodies  >8 publications with HSPA1A and Heart Diseases
 Liver Neoplasms Antibodies  >6 publications with HSPA1A and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >37 publications with HSPA1A and Blood
 Liver Antibodies  >18 publications with HSPA1A and Liver
 Brain Antibodies  >17 publications with HSPA1A and Brain
 Vascular Antibodies  >11 publications with HSPA1A and Vascular
 Heart Antibodies  >8 publications with HSPA1A and Heart
 Kidney Antibodies  >8 publications with HSPA1A and Kidney
 Nerve Antibodies  >8 publications with HSPA1A and Nerve
 Muscle Antibodies  >8 publications with HSPA1A and Muscle
 Skin Antibodies  >7 publications with HSPA1A and Skin
 Lung Antibodies  >6 publications with HSPA1A and Lung
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions