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IL-1B elisa kit :: Hamster Interleukin 1beta ELISA Kit

Scan QR to view Datasheet Catalog #    MBS283040 IL-1B elisa kit
Unit / Price
48-Strip-Wells  /  $425 +1 FREE 8GB USB
96-Strip-Wells  /  $720 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,160 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,055 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 1beta (IL-1B), ELISA Kit

 Also Known As   

Hamster Interleukin 1beta (IL-1B) ELISA Kit

 Product Gene Name   

IL-1B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Species Reactivity    Hamster
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Hamster IL-1beta. No significant cross-reactivity or interference between Hamster IL-1beta and analogues was observed.
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 Preparation and Storage    Store at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of IL-1B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL-1B purchase    MBS283040 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 1beta (IL-1B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL-1B. The ELISA analytical biochemical technique of the MBS283040 kit is based on IL-1B antibody-IL-1B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-1B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-1B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for IL-1B elisa kit

   Intended Uses: For the quantitative detection of Hamster Interleukin-1 beta (IL1B) concentration in serum, plasma and other biological fluids.

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate IL-1beta in Hamster serum, plasma. An antibody specific for IL-1beta has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL-1beta present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL-1beta is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL-1beta bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI/Uniprot data below describe general gene information for IL-1B. It may not necessarily be applicable to this product.
 NCBI GI #    6680415
 NCBI GeneID    16176
 NCBI Accession #    NP_032387.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_008361.3 [Other Products]
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 UniProt Secondary Accession #    Q2M4J6 [Other Products]
 UniProt Related Accession #    P10749 [Other Products]
 Molecular Weight    30,931 Da
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 NCBI Official Full Name    interleukin-1 beta
 NCBI Official Synonym Full Names    interleukin 1 beta
 NCBI Official Symbol    Il1b [Similar Products]
 NCBI Official Synonym Symbols   
Il-1b; IL-1beta
[Similar Products]
 NCBI Protein Information    interleukin-1 beta; IL-1 beta
 UniProt Protein Name    Interleukin-1 beta
 UniProt Gene Name    Il1b [Similar Products]
 UniProt Synonym Gene Names    IL-1 beta [Similar Products]
 UniProt Entry Name    IL1B_MOUSE
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 NCBI Summary for IL-1B    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1. The encoded protein plays a role in thymocyte proliferation and is involved in the inflammatory response. [provided by RefSeq, Aug 2015]
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 UniProt Comments for IL-1B    IL1B: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Monomer. Belongs to the IL-1 family.

Protein type: Cytokine

Cellular Component: extracellular space; cell; extracellular region; intracellular; cytosol; vesicle; secretory granule

Molecular Function: protein domain specific binding; interleukin-1 receptor binding; cytokine activity; receptor binding

Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; negative regulation of MAP kinase activity; positive regulation of JNK activity; positive regulation of nitric oxide biosynthetic process; negative regulation of glutamate secretion; activation of MAPK activity; positive regulation of apoptosis; positive regulation of interleukin-2 biosynthetic process; positive regulation of transcription, DNA-dependent; germ cell programmed cell death; negative regulation of insulin receptor signaling pathway; response to lipopolysaccharide; positive regulation of NF-kappaB import into nucleus; positive regulation of lipid catabolic process; positive regulation of glial cell differentiation; fever; positive regulation of membrane protein ectodomain proteolysis; response to carbohydrate stimulus; activation of NF-kappaB transcription factor; elevation of cytosolic calcium ion concentration; positive regulation of phagocytosis; positive regulation of T cell proliferation; positive regulation of astrocyte differentiation; neutrophil chemotaxis; positive regulation of heterotypic cell-cell adhesion; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of mitosis; interleukin-1 beta production; positive regulation of interleukin-6 production; social behavior; positive regulation of angiogenesis; negative regulation of neuron differentiation; positive regulation of cell division; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; negative regulation of lipid metabolic process; leukocyte migration; sequestering of triacylglycerol; positive regulation of interleukin-6 biosynthetic process; positive regulation of JNK cascade; negative regulation of transcription from RNA polymerase II promoter; positive regulation of stress-activated MAPK cascade; negative regulation of neurogenesis; positive regulation of interleukin-8 production; negative regulation of cell proliferation; negative regulation of lipid catabolic process; hyaluronan biosynthetic process; protein kinase B signaling cascade; lipopolysaccharide-mediated signaling pathway; regulation of I-kappaB kinase/NF-kappaB cascade; inflammatory response; aging; cytokine and chemokine mediated signaling pathway; MAPKKK cascade; positive regulation of immature T cell proliferation in the thymus; memory; response to ATP; positive regulation of interferon-gamma production; positive regulation of chemokine biosynthetic process; positive regulation of prostaglandin secretion; positive regulation of fever; immune response; positive regulation of protein amino acid phosphorylation; regulation of insulin secretion
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 Research Articles on IL-1B    1. NLRP3 inflammasome activation and IL-1beta release play a crucial role in the pathogenesis of experimental allergic asthma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL-1B elisa kitPathways associated with IL-1B elisa kit
 Reference Product  PubMed Publications
 Il6 elisa kit  >269 publications with IL-1B and Il6
 Tnf elisa kit  >265 publications with IL-1B and Tnf
 Il1a elisa kit  >191 publications with IL-1B and Il1a
 Casp1 elisa kit  >65 publications with IL-1B and Casp1
 Il1r1 elisa kit  >36 publications with IL-1B and Il1r1
 Il18 elisa kit  >31 publications with IL-1B and Il18
 Nfkb1 elisa kit  >24 publications with IL-1B and Nfkb1
 Myd88 elisa kit  >20 publications with IL-1B and Myd88
 Rela elisa kit  >18 publications with IL-1B and Rela
 Il1r2 elisa kit  >12 publications with IL-1B and Il1r2
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
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 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
Diseases associated with IL-1B elisa kitOrgans/Tissues associated with IL-1B elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >390 publications with IL-1B and Inflammation
 Necrosis Antibodies  >239 publications with IL-1B and Necrosis
 Skin Diseases Antibodies  >54 publications with IL-1B and Skin Diseases
 Stomach Neoplasms Antibodies  >41 publications with IL-1B and Stomach Neoplasms
 Arthritis, Rheumatoid Antibodies  >26 publications with IL-1B and Arthritis, Rheumatoid
 Hypersensitivity Antibodies  >23 publications with IL-1B and Hypersensitivity
 Adenocarcinoma Antibodies  >23 publications with IL-1B and Adenocarcinoma
 Asthma Antibodies  >21 publications with IL-1B and Asthma
 Myocardial Ischemia Antibodies  >19 publications with IL-1B and Myocardial Ischemia
 Colitis Antibodies  >17 publications with IL-1B and Colitis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >316 publications with IL-1B and Blood
 Lung Antibodies  >75 publications with IL-1B and Lung
 Brain Antibodies  >49 publications with IL-1B and Brain
 Bone Marrow Antibodies  >31 publications with IL-1B and Bone Marrow
 Muscle Antibodies  >26 publications with IL-1B and Muscle
 Spleen Antibodies  >11 publications with IL-1B and Spleen
 Lymph Node Antibodies  >9 publications with IL-1B and Lymph Node
 Vagina Antibodies  >5 publications with IL-1B and Vagina
 Mammary Gland Antibodies  >5 publications with IL-1B and Mammary Gland
 Thymus Antibodies  >3 publications with IL-1B and Thymus
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