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NEFH elisa kit :: Hamster Neurofilament, Heavy Polypeptide ELISA Kit

Scan QR to view Datasheet Catalog #    MBS033448 NEFH elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Neurofilament, Heavy Polypeptide (NEFH), ELISA Kit

 Also Known As   

Hamster Neurofilament, Heavy Polypeptide ELISA Kit

 Product Gene Name   

NEFH elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 22; NC_000022.10 (29876181..29887279). Location: 22q12.2
 OMIM    105400
 3D Structure    ModBase 3D Structure for P12036
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 Species Reactivity    Hamster
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NEFH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NEFH purchase    MBS033448 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neurofilament, Heavy Polypeptide (NEFH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NEFH. The ELISA analytical biochemical technique of the MBS033448 kit is based on NEFH antibody-NEFH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NEFH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NEFH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for NEFH. It may not necessarily be applicable to this product.
 NCBI GI #    32483416
 NCBI GeneID    4744
 NCBI Accession #    NP_066554.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021076.3 [Other Products]
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 UniProt Primary Accession #    P12036 [Other Products]
 UniProt Secondary Accession #    Q96HF8; Q9UJS7; Q9UQ14; B4DYY4 [Other Products]
 UniProt Related Accession #    P12036 [Other Products]
 Molecular Weight    112,479 Da
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 NCBI Official Full Name    neurofilament heavy polypeptide
 NCBI Official Synonym Full Names    neurofilament, heavy polypeptide
 NCBI Official Symbol    NEFH [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    neurofilament heavy polypeptide; NF-H; 200 kDa neurofilament protein; neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa
 UniProt Protein Name    Neurofilament heavy polypeptide
 UniProt Synonym Protein Names   
200 kDa neurofilament protein; Neurofilament triplet H protein
 Protein Family    Neurofilament heavy polypeptide
 UniProt Gene Name    NEFH [Similar Products]
 UniProt Synonym Gene Names    KIAA0845; NFH; NF-H [Similar Products]
 UniProt Entry Name    NFH_HUMAN
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 NCBI Summary for NEFH    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
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 UniProt Comments for NEFH    NFH: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. Belongs to the intermediate filament family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: mitochondrion; axon; cytoplasm; neurofilament

Molecular Function: protein binding, bridging; dynein binding; structural constituent of cytoskeleton; kinesin binding; microtubule binding; structural molecule activity; protein kinase binding

Biological Process: neurofilament bundle assembly; axonogenesis; cell projection biogenesis; microtubule cytoskeleton organization and biogenesis; peripheral nervous system neuron axonogenesis

Disease: Amyotrophic Lateral Sclerosis 1
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 Research Articles on NEFH    1. CSF and intrathecal levels and CSF/serum ratios of anti-NFH antibodies were increased in the CIS patients early developing multiple sclerosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NEFH elisa kitPathways associated with NEFH elisa kit
 Reference Product  PubMed Publications
 NEFL elisa kit  >3 publications with NEFH and NEFL
 PRPH elisa kit  >1 publications with NEFH and PRPH
 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
Diseases associated with NEFH elisa kitOrgans/Tissues associated with NEFH elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >13 publications with NEFH and Nervous System Diseases
 Neoplasms Antibodies  >7 publications with NEFH and Neoplasms
 Brain Diseases Antibodies  >4 publications with NEFH and Brain Diseases
 Drug Toxicity Antibodies  >3 publications with NEFH and Drug Toxicity
 Death Antibodies  >3 publications with NEFH and Death
 Brain Injuries Antibodies  >2 publications with NEFH and Brain Injuries
 Disease Models, Animal Antibodies  >1 publications with NEFH and Disease Models, Animal
 Atrophy Antibodies  >1 publications with NEFH and Atrophy
 Poisoning Antibodies  >1 publications with NEFH and Poisoning
 Neurotoxicity Syndromes Antibodies  >1 publications with NEFH and Neurotoxicity Syndromes
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with NEFH and Brain
 Nerve Antibodies  >7 publications with NEFH and Nerve
 Spinal Cord Antibodies  >2 publications with NEFH and Spinal Cord
 Testis Antibodies  >2 publications with NEFH and Testis
 Eye Antibodies  >2 publications with NEFH and Eye
 Ear Antibodies  >1 publications with NEFH and Ear
 Heart Antibodies  >1 publications with NEFH and Heart
 Bone Marrow Antibodies  >1 publications with NEFH and Bone Marrow
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