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PFKP elisa kit :: Hamster Phosphofructokinase- Platelet ELISA Kit

Scan QR to view Datasheet Catalog #    MBS006175 PFKP elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Phosphofructokinase- Platelet (PFKP), ELISA Kit

 Also Known As   

Hamster Phosphofructokinase- Platelet ELISA Kit

 Product Gene Name   

PFKP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 10; NC_000010.10 (3109712..3178997). Location: 10p15.3-p15.2
 OMIM    171840
 3D Structure    ModBase 3D Structure for Q01813
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 Species Reactivity    Hamster
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PFKP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PFKP purchase    MBS006175 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Phosphofructokinase- Platelet (PFKP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PFKP. The ELISA analytical biochemical technique of the MBS006175 kit is based on PFKP antibody-PFKP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PFKP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PFKP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PFKP. It may not necessarily be applicable to this product.
 NCBI GI #    71297291
 NCBI GeneID    5214
 NCBI Accession #    AAH43156.1 [Other Products]
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 UniProt Primary Accession #    Q01813 [Other Products]
 UniProt Secondary Accession #    Q5VSR7; Q5VSR8; B3KS15 [Other Products]
 UniProt Related Accession #    Q01813 [Other Products]
 Molecular Weight    85,596 Da
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 NCBI Official Full Name    PFKP protein
 NCBI Official Synonym Full Names    phosphofructokinase, platelet
 NCBI Official Symbol    PFKP [Similar Products]
 NCBI Official Synonym Symbols   
PFKF; PFK-C
[Similar Products]
 NCBI Protein Information    6-phosphofructokinase type C; phosphohexokinase; phosphofructokinase 1; phosphofructo-1-kinase isozyme C; Phosphofructokinase, platelet type; 6-phosphofructokinase, platelet type
 UniProt Protein Name    6-phosphofructokinase type C
 UniProt Synonym Protein Names   
6-phosphofructokinase, platelet type; Phosphofructo-1-kinase isozyme C; PFK-C; Phosphofructokinase 1; Phosphohexokinase
 Protein Family    ATP-dependent 6-phosphofructokinase
 UniProt Gene Name    PFKP [Similar Products]
 UniProt Synonym Gene Names    PFKF; PFK-C [Similar Products]
 UniProt Entry Name    K6PP_HUMAN
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 NCBI Summary for PFKP    The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM, Mar 2008]
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 UniProt Comments for PFKP    PFKP: phosphofructokinase, platelet type. An ubiquitous metabolic enzyme involved in the synthesis and degradation of fructose 2,6-bisphosphate. Key control step of glycolysis. An allosteric enzyme activated by ADP, AMP, or fructose bisphosphate and inhibited by ATP or citrate. Activity: ATP D-fructose 6-phosphate = ADP D-fructose 1,6-bisphosphate. The holoenzyme consists of 4 subunits. The liver and muscle enzymes are homo-tetramers of four liver or muscle isoforms, respectively. The red blood cell enzyme consists hetero-tetramers of the muscle and liver isoforms. A subunit composition with a higher proportion of platelet type subunits is found in platelets, brain and fibroblasts.

Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - galactose; Kinase, other; EC 2.7.1.11; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - pentose phosphate pathway

Chromosomal Location of Human Ortholog: 10p15.3-p15.2

Cellular Component: membrane; cytosol; nucleus

Molecular Function: metal ion binding; protein complex binding; ATP binding; 6-phosphofructokinase activity

Biological Process: glycolysis; carbohydrate metabolic process; carbohydrate phosphorylation; glucose metabolic process; pathogenesis; fructose 6-phosphate metabolic process
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 Research Articles on PFKP    1. KLF4 plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PFKP elisa kitPathways associated with PFKP elisa kit
 Reference Product  PubMed Publications
 ALDOA elisa kit  >2 publications with PFKP and ALDOA
 PFKL elisa kit  >1 publications with PFKP and PFKL
 PFKFB3 elisa kit  >1 publications with PFKP and PFKFB3
 HK2 elisa kit  >1 publications with PFKP and HK2
 PFKM elisa kit  >1 publications with PFKP and PFKM
 Products by Pathway  Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Conversion Of Glucose To Acetyl CoA And Entry Into The TCA Cycle Pathway antibodies  Conversion Of Glucose To Acetyl CoA And Entry Into The TCA Cycle Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram
Diseases associated with PFKP elisa kitOrgans/Tissues associated with PFKP elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with PFKP and Neoplasms
 Disease Models, Animal Antibodies  >2 publications with PFKP and Disease Models, Animal
 Hypertrophy Antibodies  >1 publications with PFKP and Hypertrophy
 Neoplasms, Experimental Antibodies  >1 publications with PFKP and Neoplasms, Experimental
 Hypertension Antibodies  >1 publications with PFKP and Hypertension
 Breast Neoplasms Antibodies  >1 publications with PFKP and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with PFKP and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with PFKP and Blood
 Muscle Antibodies  >4 publications with PFKP and Muscle
 Ovary Antibodies  >4 publications with PFKP and Ovary
 Liver Antibodies  >3 publications with PFKP and Liver
 Bone Antibodies  >2 publications with PFKP and Bone
 Thyroid Antibodies  >2 publications with PFKP and Thyroid
 Brain Antibodies  >2 publications with PFKP and Brain
 Heart Antibodies  >1 publications with PFKP and Heart
 Skin Antibodies  >1 publications with PFKP and Skin
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