NP_001257511.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
59,637 Da
NCBI Official Full Name
pituitary adenylate cyclase-activating polypeptide type I receptor isoform 5
NCBI Official Synonym Full Names
adenylate cyclase activating polypeptide 1 receptor 1
NCBI Official Synonym Symbols
PAC1-R; PACAPR1; PACAP-R1; PACAPR1A; PACAP-R1A [Similar Products]
NCBI Protein Information
pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R-1; PACAP-R-1A; PACAP type I receptor; PACAP type IA receptor; adenylate cyclase activating polypeptide 1 type 1 receptor; pituitary adenylate cyclase activating polypeptide receptor; pituitary adenylate cyclase activating polypeptide 1 receptor (1); pituitary adenylate cyclase-activating polypeptide type IA receptor; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
UniProt Protein Name
Pituitary adenylate cyclase-activating polypeptide type I receptor
UniProt Synonym Gene Names
UniProt Entry Name
PACR_RAT
NCBI Summary for PACAPR1
regulates neural precursor proliferation; mediates inhibitory signaling for Shh-induced cerebellar granule precursor cell proliferation [RGD, Feb 2006]
UniProt Comments for PACAPR1
ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, GPCR; GPCR, family 2; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: Golgi membrane; neuron projection; tight junction; cell surface; rough endoplasmic reticulum; cytoplasm; integral to membrane; caveola; endosome; receptor complex
Molecular Function: neuropeptide binding; ADP-ribosylation factor binding; vasoactive intestinal polypeptide receptor activity; adenylate cyclase binding
Biological Process: response to drug; development of primary female sexual characteristics; G-protein coupled receptor protein signaling pathway; cAMP-mediated signaling; response to ethanol; phospholipase C activation; positive regulation of cAMP biosynthetic process; spermatogenesis; cell differentiation; multicellular organismal response to stress; response to estradiol stimulus
Research Articles on PACAPR1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with PACAPR1 elisa kit
Diseases associated with PACAPR1 elisa kit
Organs/Tissues associated with PACAPR1 elisa kit
|