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PDXP elisa kit :: Hamster Pyridoxal /Pyridoxine Vitamin B6 -Phosphatase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS035648 PDXP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Pyridoxal /Pyridoxine Vitamin B6 -Phosphatase (PDXP), ELISA Kit

 Also Known As   

Hamster Pyridoxal /Pyridoxine Vitamin B6 -Phosphatase ELISA Kit

 Product Gene Name   

PDXP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    609246
 3D Structure    ModBase 3D Structure for Q96GD0
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 Species Reactivity    Hamster
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PDXP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PDXP purchase    MBS035648 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Pyridoxal /Pyridoxine Vitamin B6 -Phosphatase (PDXP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDXP. The ELISA analytical biochemical technique of the MBS035648 kit is based on PDXP antibody-PDXP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDXP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDXP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PDXP. It may not necessarily be applicable to this product.
 NCBI GI #    10092677
 NCBI GeneID    57026
 NCBI Accession #    NP_064711.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020315.4 [Other Products]
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 UniProt Primary Accession #    Q96GD0 [Other Products]
 UniProt Secondary Accession #    Q9UGY2 [Other Products]
 UniProt Related Accession #    Q96GD0 [Other Products]
 Molecular Weight    31,698 Da
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 NCBI Official Full Name    pyridoxal phosphate phosphatase
 NCBI Official Synonym Full Names    pyridoxal (pyridoxine, vitamin B6) phosphatase
 NCBI Official Symbol    PDXP [Similar Products]
 NCBI Official Synonym Symbols   
CIN; PLP; dJ37E16.5
[Similar Products]
 NCBI Protein Information    pyridoxal phosphate phosphatase; chronophin; PLP phosphatase
 UniProt Protein Name    Pyridoxal phosphate phosphatase
 UniProt Synonym Protein Names   
Chronophin
 Protein Family    Pyridoxal phosphate phosphatase
 UniProt Gene Name    PDXP [Similar Products]
 UniProt Synonym Gene Names    CIN; PLP; PLPP; PLP phosphatase [Similar Products]
 UniProt Entry Name    PLPP_HUMAN
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 NCBI Summary for PDXP    Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for PDXP    PDXP: Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho- tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PMP) and pyridoxine 5'-phosphate (PNP), with a highest activity with PLP followed by PNP. Homodimer. Ubiquitous. Highly expressed in all the regions of central nerve system except the spinal cord. Also expressed at high level in liver and testis. In fetus, it is weakly expressed in all organs except brain. Inhibited by NaF, Zn(2+), Ca(2+), Mn(2+) and EDTA. Belongs to the HAD-like hydrolase superfamily.

Protein type: EC 3.1.3.3; Cofactor and Vitamin Metabolism - vitamin B6; Cell cycle regulation; Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.74

Chromosomal Location of Human Ortholog: 22q12.3

Cellular Component: lamellipodium; plasma membrane; midbody; cytosol; actin cytoskeleton; cleavage furrow

Molecular Function: protein binding; phosphoserine phosphatase activity; heat shock protein binding; magnesium ion binding; phosphoprotein phosphatase activity; pyridoxal phosphatase activity

Biological Process: actin rod formation; positive regulation of actin filament depolymerization; pyridoxal phosphate catabolic process; regulation of mitosis; protein amino acid dephosphorylation; regulation of cytokinesis
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 Research Articles on PDXP    1. Splicing of SH3BP1 and CIN gene loci produces the novel brain specific splice variant BGIN.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PDXP elisa kitDiseases associated with PDXP elisa kit
 Reference Product  PubMed Publications
 PDXK elisa kit  >3 publications with PDXP and PDXK
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with PDXP and Neoplasms
 Lung Neoplasms Antibodies  >3 publications with PDXP and Lung Neoplasms
 Inflammation Antibodies  >1 publications with PDXP and Inflammation
Organs/Tissues associated with PDXP elisa kit
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with PDXP and Lung
 Liver Antibodies  >1 publications with PDXP and Liver
 Muscle Antibodies  >1 publications with PDXP and Muscle
 Blood Antibodies  >1 publications with PDXP and Blood
 Brain Antibodies  >1 publications with PDXP and Brain
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