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RXR elisa kit :: Hamster Soluble Retinoid X Receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS019404 RXR elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Soluble Retinoid X Receptor (RXR), ELISA Kit

 Also Known As   

Hamster Soluble Retinoid X Receptor ELISA Kit

 Product Gene Name   

RXR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9WTN3
 Species Reactivity    Hamster
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RXR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RXR purchase    MBS019404 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Soluble Retinoid X Receptor (RXR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RXR. The ELISA analytical biochemical technique of the MBS019404 kit is based on RXR antibody-RXR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RXR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RXR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RXR. It may not necessarily be applicable to this product.
 NCBI GI #    158524238
 NCBI GeneID    20787
 NCBI Accession #    Q9WTN3.4 [Other Products]
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 UniProt Primary Accession #    Q9WTN3 [Other Products]
 UniProt Secondary Accession #    Q3U458; Q3UDJ3; Q5SRX5; Q8C733; Q99JK7 [Other Products]
 UniProt Related Accession #    Q9WTN3 [Other Products]
 Molecular Weight    120,537 Da
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 NCBI Official Full Name    Sterol regulatory element-binding protein 1
 NCBI Official Synonym Full Names    sterol regulatory element binding transcription factor 1
 NCBI Official Symbol    Srebf1 [Similar Products]
 NCBI Official Synonym Symbols   
ADD1; ADD-1; SREBP1; bHLHd1; SREBP-1; SREBP1c; SREBP-1a; SREBP-1c; D630008H06
[Similar Products]
 NCBI Protein Information    sterol regulatory element-binding protein 1; adipocyte determination- and differentiation-dependent factor 1
 UniProt Protein Name    Sterol regulatory element-binding protein 1
 UniProt Synonym Protein Names   
Sterol regulatory element-binding transcription factor 1
 Protein Family    Retinoic acid receptor
 UniProt Gene Name    Srebf1 [Similar Products]
 UniProt Synonym Gene Names    Srebp1; SREBP-1 [Similar Products]
 UniProt Entry Name    SRBP1_MOUSE
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 UniProt Comments for RXR    SREBP-1: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. Expressed in a wide variety of tissues, most abundant in liver and adrenal gland. In fetal tissues lung and liver shows highest expression. Isoform SREBP-1C predominates in liver, adrenal gland and ovary, whereas isoform SREBP-1A predominates in hepatoma cell lines. Isoform SREBP-1A and isoform SREBP-1C are found in kidney, brain, white fat, and muscle. Belongs to the SREBP family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Membrane protein, integral; DNA-binding; Membrane protein, multi-pass

Cellular Component: Golgi apparatus; protein complex; intracellular membrane-bound organelle; membrane; endoplasmic reticulum; cytoplasm; integral to membrane; cytoplasmic vesicle; nucleus

Molecular Function: protein dimerization activity; protein binding; sterol response element binding; DNA binding; sequence-specific DNA binding; protein complex binding; chromatin binding; protein kinase binding; transcription factor activity

Biological Process: steroid metabolic process; cholesterol metabolic process; positive regulation of fatty acid biosynthetic process; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; lipid biosynthetic process; positive regulation of cholesterol biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; cellular response to starvation; negative regulation of insulin secretion; positive regulation of histone deacetylation; regulation of transcription, DNA-dependent; chemical signal regulation of heart rate; regulation of fatty acid metabolic process; insulin receptor signaling pathway; response to glucose stimulus; positive regulation of transcription from RNA polymerase II promoter; lipid metabolic process; regulation of insulin secretion
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 Research Articles on RXR    1. Adaptive responses by mouse fetus to a maternal HLE diet by downregulating SREBP1
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RXR elisa kitDiseases associated with RXR elisa kit
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Activation Of Gene Expression By SREBF (SREBP) Pathway antibodies  Activation Of Gene Expression By SREBF (SREBP) Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >825 publications with RXR and Fatty Liver
 Liver Diseases Antibodies  >417 publications with RXR and Liver Diseases
 Obesity Antibodies  >354 publications with RXR and Obesity
 Insulin Resistance Antibodies  >306 publications with RXR and Insulin Resistance
 Dyslipidemias Antibodies  >129 publications with RXR and Dyslipidemias
 Inflammation Antibodies  >126 publications with RXR and Inflammation
 Neoplasms Antibodies  >119 publications with RXR and Neoplasms
 Cardiovascular Diseases Antibodies  >117 publications with RXR and Cardiovascular Diseases
 Hyperlipidemias Antibodies  >104 publications with RXR and Hyperlipidemias
 Necrosis Antibodies  >100 publications with RXR and Necrosis
Organs/Tissues associated with RXR elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1164 publications with RXR and Liver
 Blood Antibodies  >484 publications with RXR and Blood
 Adipose Tissue Antibodies  >403 publications with RXR and Adipose Tissue
 Connective Tissue Antibodies  >267 publications with RXR and Connective Tissue
 Kidney Antibodies  >87 publications with RXR and Kidney
 Pancreas Antibodies  >71 publications with RXR and Pancreas
 Brain Antibodies  >70 publications with RXR and Brain
 Heart Antibodies  >62 publications with RXR and Heart
 Intestine Antibodies  >45 publications with RXR and Intestine
 Ovary Antibodies  >41 publications with RXR and Ovary
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