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APOB elisa kit :: Hamster apolipoprotein B (APOB) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS907181 (SPECIAL PROMOTIONAL PRICING for a limited time) APOB elisa kit
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $350 +1 FREE 8GB USB
96-Strip-Wells  /  $495 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,105 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

apolipoprotein B (APOB), ELISA Kit

★Popular Item★
 Also Known As   

Hamster apolipoprotein B, APOB ELISA Kit

 Product Synonym Names    Hamster apolipoprotein B (APOB) ELISA kit; Hamster apolipoprotein B (APOB)
 Product Gene Name   

APOB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS907181 Testing Data    Testing Data PDF
 OMIM    615558
 3D Structure    ModBase 3D Structure for P04114
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 Species Reactivity    Hamster
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 Specificity    This assay has high sensitivity and excellent specificity for detection of hamster APOB. No significant cross-reactivity or interference between hamster APOB and analogues was observed.
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 Samples    serum, plasma, tissue homogenates.
 Assay Type    Competitive (Quantitative)
 Detection Range    0.313 ug/ml -20 ug/ml.
 Sensitivity    Typically less than 0.372 ug/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of APOB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for APOB purchase    MBS907181 is a ready-to-use microwell, strip plate Competitive (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the apolipoprotein B (APOB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313 ug/ml -20 ug/ml. in biological research samples containing APOB, with an estimated sensitivity of Typically less than 0.372 ug/ml. The ELISA analytical biochemical technique of the MBS907181 kit is based on APOB antibody-APOB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APOB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APOB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Sample Manual Insert of MBS907181. Click to request current manual
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NCBI/Uniprot data below describe general gene information for APOB. It may not necessarily be applicable to this product.
 NCBI GI #    105990532
 NCBI GeneID    338
 NCBI Accession #    NP_000375.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000384.2 [Other Products]
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 UniProt Primary Accession #    P04114 [Other Products]
 UniProt Secondary Accession #    O00502; P78479; P78480; P78481; Q13779; Q13785; Q13786; Q13787; Q13788; Q4ZG63; Q53QC8 [Other Products]
 UniProt Related Accession #    P04114 [Other Products]
 Molecular Weight    515,605 Da
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 NCBI Official Full Name    apolipoprotein B-100
 NCBI Official Synonym Full Names    apolipoprotein B
 NCBI Official Symbol    APOB [Similar Products]
 NCBI Official Synonym Symbols   
FLDB; LDLCQ4
[Similar Products]
 NCBI Protein Information    apolipoprotein B-100; apoB-48; apoB-100; apo B-100; mutant Apo B 100; apolipoprotein B48; apolipoprotein B (including Ag(x) antigen)
 UniProt Protein Name    Apolipoprotein B-100
 Protein Family    Apolipoprotein
 UniProt Gene Name    APOB [Similar Products]
 UniProt Synonym Gene Names    Apo B-100; Apo B-48 [Similar Products]
 UniProt Entry Name    APOB_HUMAN
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 NCBI Summary for APOB    This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
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 UniProt Comments for APOB    APOB: Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. Defects in APOB are a cause of familial hypobetalipoproteinemia type 1 (FHBL1). A disorder characterized by highly reduced plasma concentrations of low density lipoproteins, and dietary fat malabsorption. Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia. Defects in APOB are a cause of familial ligand-defective apolipoprotein B-100 (FDB). FDB is a dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD). The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors. Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.

Protein type: Secreted; Secreted, signal peptide; Carrier

Chromosomal Location of Human Ortholog: 2p24-p23

Cellular Component: Golgi apparatus; extracellular space; endoplasmic reticulum membrane; intracellular membrane-bound organelle; endoplasmic reticulum lumen; early endosome; extracellular region; cytosol; actin cytoskeleton; chylomicron; cell soma; cytoplasm; plasma membrane; endosome membrane

Molecular Function: heparin binding; protein binding; low-density lipoprotein receptor binding; cholesterol transporter activity; phospholipid binding

Biological Process: lipoprotein catabolic process; phototransduction, visible light; response to lipopolysaccharide; response to carbohydrate stimulus; post-embryonic development; response to selenium ion; triacylglycerol catabolic process; retinoid metabolic process; transmembrane transport; receptor-mediated endocytosis; cholesterol metabolic process; nervous system development; cholesterol transport; in utero embryonic development; response to virus; regulation of cholesterol biosynthetic process; lipoprotein metabolic process; cholesterol efflux; cholesterol homeostasis; sperm motility; fertilization; lipoprotein biosynthetic process; lipoprotein transport; artery morphogenesis; spermatogenesis; blood coagulation; triacylglycerol mobilization; leukocyte migration

Disease: Hypercholesterolemia, Autosomal Dominant, Type B; Hypobetalipoproteinemia, Familial, 1
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 Research Articles on APOB    1. XbaI and EcoRI polymorphisms were associated with presence of plaques on carotid arteries. Plasma ApoB level was not independently associated with ultrasonographic phenotypes of carotid atherosclerosis in patients with diabetes mellitus.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with APOB elisa kitPathways associated with APOB elisa kit
 Reference Product  PubMed Publications
 APOA1 elisa kit  >369 publications with APOB and APOA1
 LDLR elisa kit  >322 publications with APOB and LDLR
 LIPC elisa kit  >26 publications with APOB and LIPC
 MTTP elisa kit  >23 publications with APOB and MTTP
 BGN elisa kit  >8 publications with APOB and BGN
 HSPA8 elisa kit  >1 publications with APOB and HSPA8
 Products by Pathway  Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Chylomicron-mediated Lipid Transport Pathway antibodies  Chylomicron-mediated Lipid Transport Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 LDL-mediated Lipid Transport Pathway antibodies  LDL-mediated Lipid Transport Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with APOB elisa kitOrgans/Tissues associated with APOB elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3045 publications with APOB and Cardiovascular Diseases
 Dyslipidemias Antibodies  >2688 publications with APOB and Dyslipidemias
 Atherosclerosis Antibodies  >2289 publications with APOB and Atherosclerosis
 Hyperlipidemias Antibodies  >2263 publications with APOB and Hyperlipidemias
 Coronary Disease Antibodies  >1703 publications with APOB and Coronary Disease
 Myocardial Ischemia Antibodies  >1561 publications with APOB and Myocardial Ischemia
 Heart Diseases Antibodies  >1463 publications with APOB and Heart Diseases
 Arteriosclerosis Antibodies  >1451 publications with APOB and Arteriosclerosis
 Hypercholesterolemia Antibodies  >1327 publications with APOB and Hypercholesterolemia
 HYPERCHOLESTEROLEMIA, AUTOSOMAL DOMINANT, TYPE B Antibodies  >660 publications with APOB and HYPERCHOLESTEROLEMIA, AUTOSOMAL DOMINANT, TYPE B
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7364 publications with APOB and Blood
 Liver Antibodies  >2022 publications with APOB and Liver
 Heart Antibodies  >1258 publications with APOB and Heart
 Intestine Antibodies  >544 publications with APOB and Intestine
 Kidney Antibodies  >374 publications with APOB and Kidney
 Muscle Antibodies  >285 publications with APOB and Muscle
 Brain Antibodies  >122 publications with APOB and Brain
 Lung Antibodies  >105 publications with APOB and Lung
 Embryonic Tissue Antibodies  >52 publications with APOB and Embryonic Tissue
 Spleen Antibodies  >50 publications with APOB and Spleen
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