NP_009031.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,933 Da
NCBI Official Full Name
ATP synthase subunit e, mitochondrial
NCBI Official Synonym Full Names
ATP synthase, H+ transporting, mitochondrial Fo complex subunit E
NCBI Official Synonym Symbols
NCBI Protein Information
ATP synthase subunit e, mitochondrial
UniProt Protein Name
ATP synthase subunit e, mitochondrial
UniProt Synonym Gene Names
UniProt Entry Name
ATP5I_HUMAN
NCBI Summary for ATP5I
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
UniProt Comments for ATP5I
ATP5I: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. Belongs to the ATPase e subunit family.
Protein type: Energy Metabolism - oxidative phosphorylation; Mitochondrial; EC 3.6.3.14
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrion
Molecular Function: ATPase activity; hydrogen ion transmembrane transporter activity; transmembrane transporter activity
Biological Process: cellular metabolic process; mitochondrial ATP synthesis coupled proton transport
Research Articles on ATP5I
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Products associated with ATP5I elisa kit
Pathways associated with ATP5I elisa kit
Diseases associated with ATP5I elisa kit
Organs/Tissues associated with ATP5I elisa kit
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