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APA IgG elisa kit :: Horse Anthrax Protective Antigen IgG ELISA Kit

Scan QR to view Datasheet Catalog #    MBS006943 APA IgG elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Anthrax Protective Antigen IgG (APA IgG), ELISA Kit

 Also Known As   

Horse Anthrax Protective Antigen IgG ELISA Kit

 Product Gene Name   

APA IgG elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 3; NC_000003.11 (52255096..52260179, complement). Location: 3p21.3
 OMIM    605474
 3D Structure    ModBase 3D Structure for Q9NR96
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 Species Reactivity    Horse
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of APA IgG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for APA IgG purchase    MBS006943 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Anthrax Protective Antigen IgG (APA IgG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing APA IgG. The ELISA analytical biochemical technique of the MBS006943 kit is based on APA IgG antibody-APA IgG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APA IgG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APA IgG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for APA IgG. It may not necessarily be applicable to this product.
 NCBI GI #    8394456
 NCBI GeneID    54106
 NCBI Accession #    NP_059138.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_017442.3 [Other Products]
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 UniProt Primary Accession #    Q9NR96 [Other Products]
 UniProt Secondary Accession #    Q6UVZ2; Q9HD68; Q9HD69; Q9HD70; Q9NYC2; Q9NYC3; B3Y661; D1CS56 [Other Products]
 UniProt Related Accession #    Q9NR96 [Other Products]
 Molecular Weight    115,860 Da
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 NCBI Official Full Name    toll-like receptor 9
 NCBI Official Synonym Full Names    toll-like receptor 9
 NCBI Official Symbol    TLR9 [Similar Products]
 NCBI Official Synonym Symbols   
CD289
[Similar Products]
 NCBI Protein Information    toll-like receptor 9
 UniProt Protein Name    Toll-like receptor 9
 UniProt Gene Name    TLR9 [Similar Products]
 UniProt Entry Name    TLR9_HUMAN
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 NCBI Summary for APA IgG    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
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 UniProt Comments for APA IgG    TLR9: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. Interacts with MYD88 via their respective TIR domains. Interacts (via transmembrane domain) with UNC93B1. Interacts with CD300LH; the interaction may promote full activation of TLR9-triggered innate responses. Interacts with BTK. Interacts with CNPY3 and HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum. Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver. Belongs to the Toll-like receptor family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; lysosome; basolateral plasma membrane; endoplasmic reticulum; apical plasma membrane; cytoplasm; extracellular region; plasma membrane; integral to membrane; endosome membrane; endosome

Molecular Function: interleukin-1 receptor binding; transmembrane receptor activity; siRNA binding

Biological Process: positive regulation of JNK activity; regulation of cytokine secretion; positive regulation of interleukin-12 production; maintenance of gastrointestinal epithelium; positive regulation of JNK cascade; positive regulation of interferon-alpha biosynthetic process; positive regulation of NF-kappaB import into nucleus; defense response to Gram-negative bacterium; positive regulation of interleukin-18 production; positive regulation of interleukin-10 production; activation of NF-kappaB transcription factor; positive regulation of interleukin-8 production; response to molecule of bacterial origin; positive regulation of interferon-beta production; negative regulation of interleukin-8 production; negative regulation of interleukin-6 production; inflammatory response; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-6 production; positive regulation of tumor necrosis factor production; positive regulation of chemokine production; positive regulation of toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; inhibition of NF-kappaB transcription factor; defense response to bacterium; positive regulation of interferon-beta biosynthetic process; insulin receptor signaling pathway; negative regulation of toll-like receptor signaling pathway; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; I-kappaB phosphorylation; positive regulation of inflammatory response; positive regulation of interferon-gamma biosynthetic process; positive regulation of nitric-oxide synthase biosynthetic process
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 Research Articles on APA IgG    1. role of TLR-9 in antiviral innate immune sensing of MVMp and H-1PV
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with APA IgG elisa kitPathways associated with APA IgG elisa kit
 Reference Product  PubMed Publications
 TLR7 elisa kit  >616 publications with APA IgG and TLR7
 TLR3 elisa kit  >491 publications with APA IgG and TLR3
 MYD88 elisa kit  >408 publications with APA IgG and MYD88
 CD40 elisa kit  >145 publications with APA IgG and CD40
 CD86 elisa kit  >109 publications with APA IgG and CD86
 CTSB elisa kit  >2 publications with APA IgG and CTSB
 HSP90B1 elisa kit  >2 publications with APA IgG and HSP90B1
 CTSK elisa kit  >1 publications with APA IgG and CTSK
 CNPY3 elisa kit  >1 publications with APA IgG and CNPY3
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 IGF1R Signaling Cascade Pathway antibodies  IGF1R Signaling Cascade Pathway Diagram
 IRS-mediated Signalling Pathway antibodies  IRS-mediated Signalling Pathway Diagram
 IRS-related Events Pathway antibodies  IRS-related Events Pathway Diagram
 IRS-related Events Triggered By IGF1R Pathway antibodies  IRS-related Events Triggered By IGF1R Pathway Diagram
Diseases associated with APA IgG elisa kitOrgans/Tissues associated with APA IgG elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >506 publications with APA IgG and Inflammation
 Necrosis Antibodies  >367 publications with APA IgG and Necrosis
 Disease Models, Animal Antibodies  >207 publications with APA IgG and Disease Models, Animal
 Nervous System Diseases Antibodies  >97 publications with APA IgG and Nervous System Diseases
 Hepatitis Antibodies  >78 publications with APA IgG and Hepatitis
 Cardiovascular Diseases Antibodies  >70 publications with APA IgG and Cardiovascular Diseases
 Kidney Diseases Antibodies  >61 publications with APA IgG and Kidney Diseases
 Brain Diseases Antibodies  >50 publications with APA IgG and Brain Diseases
 Drug Toxicity Antibodies  >38 publications with APA IgG and Drug Toxicity
 Lung Neoplasms Antibodies  >34 publications with APA IgG and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1299 publications with APA IgG and Blood
 Lymph Node Antibodies  >103 publications with APA IgG and Lymph Node
 Lymph Antibodies  >94 publications with APA IgG and Lymph
 Thymus Antibodies  >16 publications with APA IgG and Thymus
 Tonsil Antibodies  >16 publications with APA IgG and Tonsil
 Trachea Antibodies  >5 publications with APA IgG and Trachea
 Thyroid Antibodies  >3 publications with APA IgG and Thyroid
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