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FGF-23 elisa kit :: Horse Fibroblast Growth Factor 23 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS018247 FGF-23 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fibroblast Growth Factor 23 (FGF-23), ELISA Kit

 Also Known As   

Horse Fibroblast Growth Factor 23 ELISA Kit

 Product Gene Name   

FGF-23 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 12; NC_000012.11 (4477393..4488894, complement). Location: 12p13.3
 OMIM    193100
 3D Structure    ModBase 3D Structure for Q9GZV9
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 Species Reactivity    Horse
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of FGF-23 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FGF-23 purchase    MBS018247 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fibroblast Growth Factor 23 (FGF-23) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FGF-23. The ELISA analytical biochemical technique of the MBS018247 kit is based on FGF-23 antibody-FGF-23 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FGF-23 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FGF-23. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FGF-23. It may not necessarily be applicable to this product.
 NCBI GI #    10190674
 NCBI GeneID    8074
 NCBI Accession #    NP_065689.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020638.2 [Other Products]
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 UniProt Primary Accession #    Q9GZV9 [Other Products]
 UniProt Secondary Accession #    Q4V758 [Other Products]
 UniProt Related Accession #    Q9GZV9 [Other Products]
 Molecular Weight    27,954 Da
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 NCBI Official Full Name    fibroblast growth factor 23
 NCBI Official Synonym Full Names    fibroblast growth factor 23
 NCBI Official Symbol    FGF23 [Similar Products]
 NCBI Official Synonym Symbols   
ADHR; FGFN; HYPF; HPDR2; PHPTC
[Similar Products]
 NCBI Protein Information    fibroblast growth factor 23; phosphatonin; tumor-derived hypophosphatemia inducing factor
 UniProt Protein Name    Fibroblast growth factor 23
 UniProt Synonym Protein Names   
Phosphatonin; Tumor-derived hypophosphatemia-inducing factor
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    FGF23 [Similar Products]
 UniProt Synonym Gene Names    HYPF; FGF-23 [Similar Products]
 UniProt Entry Name    FGF23_HUMAN
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 NCBI Summary for FGF-23    This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]
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 UniProt Comments for FGF-23    FGF23: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR). ADHR is characterized by low serum phosphorus concentrations, rickets, osteomalacia, leg deformities, short stature, bone pain and dental abscesses. Defects in FGF23 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC). HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Belongs to the heparin-binding growth factors family.

Protein type: Secreted, signal peptide; Cytokine; Secreted

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: extracellular space; extracellular region

Molecular Function: growth factor activity; type 1 fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of bone mineralization; cellular phosphate ion homeostasis; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; negative regulation of hormone secretion; positive regulation of transcription, DNA-dependent; insulin receptor signaling pathway; innate immune response; negative regulation of osteoblast differentiation; phosphate ion homeostasis; cell differentiation; phosphate metabolic process; vitamin D catabolic process

Disease: Hypophosphatemic Rickets, Autosomal Dominant
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 Research Articles on FGF-23    1. The prevalence of CAAC is increased with the decline in the kidney function. FGF23 is independently related to CAAC in patients with CKD who are not on dialysis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FGF-23 elisa kitPathways associated with FGF-23 elisa kit
 Reference Product  PubMed Publications
 PTH elisa kit  >202 publications with FGF-23 and PTH
 PHEX elisa kit  >87 publications with FGF-23 and PHEX
 FGFR1 elisa kit  >41 publications with FGF-23 and FGFR1
 GALNT3 elisa kit  >36 publications with FGF-23 and GALNT3
 MEPE elisa kit  >24 publications with FGF-23 and MEPE
 FGFR3 elisa kit  >11 publications with FGF-23 and FGFR3
 FGFR2 elisa kit  >10 publications with FGF-23 and FGFR2
 FGFR4 elisa kit  >9 publications with FGF-23 and FGFR4
 FGF1 elisa kit  >5 publications with FGF-23 and FGF1
 Products by Pathway  Pathway Diagram
 Activated Point Mutants Of FGFR2 Pathway antibodies  Activated Point Mutants Of FGFR2 Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
Diseases associated with FGF-23 elisa kitOrgans/Tissues associated with FGF-23 elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >320 publications with FGF-23 and Kidney Diseases
 Rickets Antibodies  >180 publications with FGF-23 and Rickets
 Phosphorus Metabolism Disorders Antibodies  >168 publications with FGF-23 and Phosphorus Metabolism Disorders
 Bone Diseases, Metabolic Antibodies  >166 publications with FGF-23 and Bone Diseases, Metabolic
 Hyperphosphatemia Antibodies  >129 publications with FGF-23 and Hyperphosphatemia
 Renal Insufficiency Antibodies  >124 publications with FGF-23 and Renal Insufficiency
 Hyperparathyroidism, Secondary Antibodies  >86 publications with FGF-23 and Hyperparathyroidism, Secondary
 Calcinosis Antibodies  >78 publications with FGF-23 and Calcinosis
 Hypophosphatemic Rickets, Autosomal Dominant Antibodies  >63 publications with FGF-23 and Hypophosphatemic Rickets, Autosomal Dominant
 Hypertension Antibodies  >54 publications with FGF-23 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >8 publications with FGF-23 and Embryonic Tissue
 Testis Antibodies  >1 publications with FGF-23 and Testis
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