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HNRNP A2 elisa kit :: Horse Heterogeneous Nuclear Ribonucleoprotein A2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS006152 HNRNP A2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Heterogeneous Nuclear Ribonucleoprotein A2 (HNRNP A2), ELISA Kit

 Also Known As   

Horse Heterogeneous Nuclear Ribonucleoprotein A2 ELISA Kit

 Product Gene Name   

HNRNP A2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    164017
 3D Structure    ModBase 3D Structure for P09651
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 Species Reactivity    Horse
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HNRNP A2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HNRNP A2 purchase    MBS006152 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Heterogeneous Nuclear Ribonucleoprotein A2 (HNRNP A2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HNRNP A2. The ELISA analytical biochemical technique of the MBS006152 kit is based on HNRNP A2 antibody-HNRNP A2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HNRNP A2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HNRNP A2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for HNRNP A2. It may not necessarily be applicable to this product.
 NCBI GI #    14043070
 NCBI GeneID    3178
 NCBI Accession #    NP_112420.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_031157.2 [Other Products]
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 UniProt Primary Accession #    P09651 [Other Products]
 UniProt Secondary Accession #    Q3MIB7; Q6PJZ7; A8K4Z8 [Other Products]
 UniProt Related Accession #    P09651 [Other Products]
 Molecular Weight    38,747 Da
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 NCBI Official Full Name    heterogeneous nuclear ribonucleoprotein A1 isoform b
 NCBI Official Synonym Full Names    heterogeneous nuclear ribonucleoprotein A1
 NCBI Official Symbol    HNRNPA1 [Similar Products]
 NCBI Official Synonym Symbols   
ALS19; ALS20; HNRPA1; IBMPFD3; HNRPA1L3; hnRNP A1; hnRNP-A1
[Similar Products]
 NCBI Protein Information    heterogeneous nuclear ribonucleoprotein A1; hnRNP A1-like 3; hnRNP core protein A1; helix-destabilizing protein; hnRNP core protein A1-like 3; single-strand RNA-binding protein; single-strand DNA-binding protein UP1; nuclear ribonucleoprotein particle A1 protein; heterogeneous nuclear ribonucleoprotein B2 protein; heterogeneous nuclear ribonucleoprotein A1B protein; heterogeneous nuclear ribonucleoprotein core protein A1; Putative heterogeneous nuclear ribonucleoprotein A1-like 3
 UniProt Protein Name    Heterogeneous nuclear ribonucleoprotein A1
 UniProt Synonym Protein Names   
Helix-destabilizing protein; Single-strand RNA-binding protein; hnRNP core protein A1
 Protein Family    Heterogeneous nuclear ribonucleoprotein
 UniProt Gene Name    HNRNPA1 [Similar Products]
 UniProt Synonym Gene Names    HNRPA1; hnRNP A1 [Similar Products]
 UniProt Entry Name    ROA1_HUMAN
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 NCBI Summary for HNRNP A2    This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HNRNP A2    hnRNP A1: Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication. Identified in the spliceosome C complex. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with SEPT6. Interacts with HCV NS5B and with the 5'-UTR and 3'-UTR of HCV RNA. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; RNA-binding; Spliceosome; Nuclear export

Chromosomal Location of Human Ortholog: 12q13.1

Cellular Component: nucleoplasm; spliceosome; intermediate filament cytoskeleton; membrane; cytoplasm; ribonucleoprotein complex

Molecular Function: protein binding; single-stranded RNA binding; RNA binding; nucleotide binding; single-stranded DNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; mRNA transport; viral reproduction; RNA export from nucleus; RNA splicing; nuclear import; nuclear export; gene expression; mRNA processing

Disease: Inclusion Body Myopathy With Early-onset Paget Disease With Or Without Frontotemporal Dementia 3; Amyotrophic Lateral Sclerosis 20
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 Research Articles on HNRNP A2    1. Data reveal three distinct enthalpic contributions from the interactions of hnRNP Al (UP1) with the Na+ form of G-quadruplex DNA.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HNRNP A2 elisa kitPathways associated with HNRNP A2 elisa kit
 Reference Product  PubMed Publications
 PRMT1 elisa kit  >2 publications with HNRNP A2 and PRMT1
 HNRNPK elisa kit  >1 publications with HNRNP A2 and HNRNPK
 KHDRBS1 elisa kit  >1 publications with HNRNP A2 and KHDRBS1
 HNRNPC elisa kit  >1 publications with HNRNP A2 and HNRNPC
 Products by Pathway  Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
Organs/Tissues associated with HNRNP A2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with HNRNP A2 and Brain
 Muscle Antibodies  >10 publications with HNRNP A2 and Muscle
 Kidney Antibodies  >5 publications with HNRNP A2 and Kidney
 Heart Antibodies  >5 publications with HNRNP A2 and Heart
 Liver Antibodies  >4 publications with HNRNP A2 and Liver
 Blood Antibodies  >4 publications with HNRNP A2 and Blood
 Bone Antibodies  >4 publications with HNRNP A2 and Bone
 Spinal Cord Antibodies  >4 publications with HNRNP A2 and Spinal Cord
 Lung Antibodies  >2 publications with HNRNP A2 and Lung
 Vascular Antibodies  >2 publications with HNRNP A2 and Vascular
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