NP_113786.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
16,294 Da
NCBI Official Full Name
phospholipase A2, membrane associated
NCBI Official Synonym Full Names
phospholipase A2, group IIA (platelets, synovial fluid)
NCBI Official Synonym Symbols
NCBI Protein Information
phospholipase A2, membrane associated; GIIC sPLA2; platelet phospholipase A2; group IIA phospholipase A2; eted enzyme type IIA phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A
UniProt Protein Name
Phospholipase A2, membrane associated
UniProt Synonym Protein Names
GIIC sPLA2; Group IIA phospholipase A2; Phosphatidylcholine 2-acylhydrolase 2A
UniProt Entry Name
PA2GA_RAT
NCBI Summary for PL-A2
hydrolyzes acyl group at the sn-2 position of phospholipids, forming non-esterified fatty acids and lysophospholipids; plays a critical role in inflammation; induces proliferation of smooth muscle cells [RGD, Feb 2006]
UniProt Comments for PL-A2
Function: Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Catalytic activity: Phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
Cofactor: Binds 1 calcium ion per subunit
By similarity.
Subcellular location: Membrane; Peripheral membrane protein.
Miscellaneous: Group II phospholipase A2 is found in many cells and also extracellularly. The membrane-bound and secreted forms are identical and are encoded by a single gene.
Sequence similarities: Belongs to the phospholipase A2 family.
Research Articles on PL-A2
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Products associated with PL-A2 elisa kit
Pathways associated with PL-A2 elisa kit
Diseases associated with PL-A2 elisa kit
Organs/Tissues associated with PL-A2 elisa kit
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