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SERT elisa kit :: Horse Serotonin Transporter ELISA Kit

Scan QR to view Datasheet Catalog #    MBS030769 SERT elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Serotonin Transporter (SERT), ELISA Kit

 Also Known As   

Horse Serotonin Transporter ELISA Kit

 Product Gene Name   

SERT elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    103780
 3D Structure    ModBase 3D Structure for P31645
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 Species Reactivity    Horse
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SERT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SERT purchase    MBS030769 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Serotonin Transporter (SERT) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SERT. The ELISA analytical biochemical technique of the MBS030769 kit is based on SERT antibody-SERT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SERT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SERT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SERT. It may not necessarily be applicable to this product.
 NCBI GI #    300444
 NCBI GeneID    6532
 NCBI Accession #    AAB26687.1 [Other Products]
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 UniProt Primary Accession #    P31645 [Other Products]
 UniProt Secondary Accession #    Q5EE02 [Other Products]
 UniProt Related Accession #    P31645; AAB26687 [Other Products]
 Molecular Weight    70,325 Da
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 NCBI Official Full Name    serotonin transporter, serotonin uptake site, 5-HT uptake site
 NCBI Official Synonym Full Names    solute carrier family 6 (neurotransmitter transporter), member 4
 NCBI Official Symbol    SLC6A4 [Similar Products]
 NCBI Official Synonym Symbols   
HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR
[Similar Products]
 NCBI Protein Information    sodium-dependent serotonin transporter; 5HT transporter; serotonin transporter 1; 5-hydroxytryptamine transporter; Na+/Cl- dependent serotonin transporter; 5-hydroxytryptamine (serotonin) transporter; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
 UniProt Protein Name    Sodium-dependent serotonin transporter
 UniProt Synonym Protein Names   
5HT transporter; 5HTT; Solute carrier family 6 member 4
 Protein Family    Sodium-dependent serotonin transporter
 UniProt Gene Name    SLC6A4 [Similar Products]
 UniProt Synonym Gene Names    HTT; SERT; 5HTT [Similar Products]
 UniProt Entry Name    SC6A4_HUMAN
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 NCBI Summary for SERT    This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SERT    SERT: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.

Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: neuron projection; integral to plasma membrane; plasma membrane; endomembrane system; endosome membrane; cytosol; lipid raft

Molecular Function: actin filament binding; serotonin transmembrane transporter activity; protein binding; protein homodimerization activity; serotonin:sodium symporter activity; myosin binding; cocaine binding; syntaxin-1 binding; monoamine transmembrane transporter activity; nitric-oxide synthase binding; Rab GTPase binding

Biological Process: circadian rhythm; response to drug; vasoconstriction; response to toxin; monoamine transport; positive regulation of cell cycle; thalamus development; social behavior; negative regulation of organ growth; serotonin uptake; negative regulation of synaptic transmission, dopaminergic; response to estradiol stimulus; protein oligomerization; memory; negative regulation of granule cell precursor proliferation; negative regulation of neuron differentiation; response to hypoxia; brain morphogenesis; sperm ejaculation; serotonin transport; transmembrane transport; response to nutrient; protein homooligomerization

Disease: Obsessive-compulsive Disorder; Anxiety
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 Research Articles on SERT    1. Our results suggest, for the first time, a significant relationship between functional SLC6A4 and COMT polymorphisms with specific human circadian phenotypes
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SERT elisa kitPathways associated with SERT elisa kit
 Reference Product  PubMed Publications
 DRD4 elisa kit  >100 publications with SERT and DRD4
 HTR1A elisa kit  >42 publications with SERT and HTR1A
 PPP2CA elisa kit  >4 publications with SERT and PPP2CA
 SEC24D elisa kit  >2 publications with SERT and SEC24D
 ERP44 elisa kit  >1 publications with SERT and ERP44
 MARCKSL1 elisa kit  >1 publications with SERT and MARCKSL1
 PRKG1 elisa kit  >1 publications with SERT and PRKG1
 AKT1 elisa kit  >1 publications with SERT and AKT1
 Products by Pathway  Pathway Diagram
 Monoamine Transport Pathway antibodies  Monoamine Transport Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
 Serotonergic Synapse Pathway antibodies  Serotonergic Synapse Pathway Diagram
 Serotonin Transporter Activity Pathway antibodies  Serotonin Transporter Activity Pathway Diagram
 Synaptic Vesicle Pathway antibodies  Synaptic Vesicle Pathway Diagram
Diseases associated with SERT elisa kitOrgans/Tissues associated with SERT elisa kit
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >1364 publications with SERT and Mental Disorders
 Mood Disorders Antibodies  >626 publications with SERT and Mood Disorders
 Depressive Disorder Antibodies  >462 publications with SERT and Depressive Disorder
 Anxiety Disorders Antibodies  >345 publications with SERT and Anxiety Disorders
 Nervous System Diseases Antibodies  >305 publications with SERT and Nervous System Diseases
 Depressive Disorder, Major Antibodies  >304 publications with SERT and Depressive Disorder, Major
 Brain Diseases Antibodies  >224 publications with SERT and Brain Diseases
 Substance-Related Disorders Antibodies  >209 publications with SERT and Substance-Related Disorders
 Bipolar Disorder Antibodies  >147 publications with SERT and Bipolar Disorder
 Alcoholism Antibodies  >145 publications with SERT and Alcoholism
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1370 publications with SERT and Brain
 Intestine Antibodies  >38 publications with SERT and Intestine
 Liver Antibodies  >37 publications with SERT and Liver
 Lung Antibodies  >37 publications with SERT and Lung
 Placenta Antibodies  >30 publications with SERT and Placenta
 Bone Antibodies  >16 publications with SERT and Bone
 Mouth Antibodies  >12 publications with SERT and Mouth
 Connective Tissue Antibodies  >7 publications with SERT and Connective Tissue
 Pancreas Antibodies  >4 publications with SERT and Pancreas
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