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STAT4 elisa kit :: Horse Signal Transducer and Activator of Transcription 4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS018216 STAT4 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Signal Transducer and Activator of Transcription 4 (STAT4), ELISA Kit

 Also Known As   

Horse Signal Transducer and Activator of Transcription 4 ELISA Kit

 Product Gene Name   

STAT4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 2; NC_000002.11 (191894302..192016322, complement). Location: 2q32.2-q32.3
 OMIM    180300
 3D Structure    ModBase 3D Structure for Q14765
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 Species Reactivity    Horse
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of STAT4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for STAT4 purchase    MBS018216 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Signal Transducer and Activator of Transcription 4 (STAT4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing STAT4. The ELISA analytical biochemical technique of the MBS018216 kit is based on STAT4 antibody-STAT4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect STAT4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, STAT4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for STAT4. It may not necessarily be applicable to this product.
 NCBI GI #    4507255
 NCBI GeneID    6775
 NCBI Accession #    NP_003142.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003151.3 [Other Products]
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 UniProt Primary Accession #    Q14765 [Other Products]
 UniProt Secondary Accession #    Q96NZ6 [Other Products]
 UniProt Related Accession #    Q14765 [Other Products]
 Molecular Weight    85,941 Da
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 NCBI Official Full Name    signal transducer and activator of transcription 4
 NCBI Official Synonym Full Names    signal transducer and activator of transcription 4
 NCBI Official Symbol    STAT4 [Similar Products]
 NCBI Official Synonym Symbols   
SLEB11
[Similar Products]
 NCBI Protein Information    signal transducer and activator of transcription 4
 UniProt Protein Name    Signal transducer and activator of transcription 4
 Protein Family    Signal transducer and activator of transcription
 UniProt Gene Name    STAT4 [Similar Products]
 UniProt Entry Name    STAT4_HUMAN
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 NCBI Summary for STAT4    The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
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 UniProt Comments for STAT4    STAT4: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 2q32.2-q32.3

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: protein binding; signal transducer activity; sequence-specific DNA binding; transcription factor activity

Biological Process: cell proliferation; transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; positive regulation of transcription from RNA polymerase II promoter; JAK-STAT cascade; protein amino acid phosphorylation

Disease: Systemic Lupus Erythematosus, Susceptibility To, 11
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 Research Articles on STAT4    1. data provide a new information that the STAT4 (rs3024912 and rs3024908) polymorphisms may be the underlying cause of membranous glomerulonephritis, and these polymorphisms revealed by this study warrant further investigation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with STAT4 elisa kitPathways associated with STAT4 elisa kit
 Reference Product  PubMed Publications
 STAT3 elisa kit  >167 publications with STAT4 and STAT3
 JUN elisa kit  >91 publications with STAT4 and JUN
 TYK2 elisa kit  >51 publications with STAT4 and TYK2
 IL12RB2 elisa kit  >34 publications with STAT4 and IL12RB2
 IFNG elisa kit  >23 publications with STAT4 and IFNG
 IL12RB1 elisa kit  >21 publications with STAT4 and IL12RB1
 IRF1 elisa kit  >13 publications with STAT4 and IRF1
 CREBBP elisa kit  >3 publications with STAT4 and CREBBP
 PIAS2 elisa kit  >1 publications with STAT4 and PIAS2
 Products by Pathway  Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 Hepatitis B Pathway antibodies  Hepatitis B Pathway Diagram
 IL12 Signaling Mediated By STAT4 Pathway antibodies  IL12 Signaling Mediated By STAT4 Pathway Diagram
 IL12-mediated Signaling Events Pathway antibodies  IL12-mediated Signaling Events Pathway Diagram
 IL23-mediated Signaling Events Pathway antibodies  IL23-mediated Signaling Events Pathway Diagram
 IL27-mediated Signaling Events Pathway antibodies  IL27-mediated Signaling Events Pathway Diagram
 Inflammatory Bowel Disease Pathway antibodies  Inflammatory Bowel Disease Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 TSLP Signaling Pathway antibodies  TSLP Signaling Pathway Diagram
Diseases associated with STAT4 elisa kitOrgans/Tissues associated with STAT4 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >137 publications with STAT4 and Inflammation
 Arthritis, Rheumatoid Antibodies  >105 publications with STAT4 and Arthritis, Rheumatoid
 Lupus Erythematosus, Systemic Antibodies  >86 publications with STAT4 and Lupus Erythematosus, Systemic
 Necrosis Antibodies  >71 publications with STAT4 and Necrosis
 Nervous System Diseases Antibodies  >62 publications with STAT4 and Nervous System Diseases
 Neoplasms Antibodies  >54 publications with STAT4 and Neoplasms
 Cardiovascular Diseases Antibodies  >36 publications with STAT4 and Cardiovascular Diseases
 Liver Diseases Antibodies  >26 publications with STAT4 and Liver Diseases
 Scleroderma, Systemic Antibodies  >18 publications with STAT4 and Scleroderma, Systemic
 Kidney Diseases Antibodies  >17 publications with STAT4 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >612 publications with STAT4 and Blood
 Spleen Antibodies  >73 publications with STAT4 and Spleen
 Skin Antibodies  >52 publications with STAT4 and Skin
 Lung Antibodies  >45 publications with STAT4 and Lung
 Lymph Node Antibodies  >30 publications with STAT4 and Lymph Node
 Heart Antibodies  >28 publications with STAT4 and Heart
 Intestine Antibodies  >27 publications with STAT4 and Intestine
 Bone Marrow Antibodies  >15 publications with STAT4 and Bone Marrow
 Kidney Antibodies  >15 publications with STAT4 and Kidney
 Brain Antibodies  >15 publications with STAT4 and Brain
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