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PLCB1 elisa kit :: Human 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase beta 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7226163 PLCB1 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase beta 1 (PLCB1), ELISA Kit

★Popular Item★
 Also Known As   

Human 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase beta 1 ELISA Kit

 Product Synonym Names    Human 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase b 1 ELISA Kit
 Product Gene Name   

PLCB1 elisa kit

[Similar Products]
 Product Synonym Gene Name    PLCB1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 613722
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 Species Reactivity    Human
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    0.5-10ng/mL
 Sensitivity    0.1ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PLCB1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PLCB1 purchase    MBS7226163 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase beta 1 (PLCB1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.5-10ng/mL in biological research samples containing PLCB1, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS7226163 kit is based on PLCB1 antibody-PLCB1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLCB1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLCB1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for PLCB1 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for PLCB1. It may not necessarily be applicable to this product.
 NCBI GI #    12083581
 NCBI GeneID    23236
 NCBI Accession #    NP_056007.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_015192.3 [Other Products]
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 UniProt Secondary Accession #    O60325; Q17RQ6; Q5TFF7; Q5TGC9; Q8IV93; Q9BQW2; Q9H4H2; Q9H8H5; Q9NQ65; D3DW12; D3DW13 [Other Products]
 UniProt Related Accession #    Q9NQ66 [Other Products]
 Molecular Weight    133,703 Da
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 NCBI Official Full Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform a
 NCBI Official Synonym Full Names    phospholipase C, beta 1 (phosphoinositide-specific)
 NCBI Official Symbol    PLCB1 [Similar Products]
 NCBI Official Synonym Symbols   
PLC-I; EIEE12; PI-PLC; PLC154; PLCB1A; PLCB1B; PLC-154
[Similar Products]
 NCBI Protein Information    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; PLC-beta-1; phospholipase C-I; phosphoinositidase C; inositoltrisphosphohydrolase; triphosphoinositide phosphodiesterase; monophosphatidylinositol phosphodiesterase; 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
 UniProt Protein Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
 UniProt Synonym Protein Names   
PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1
 Protein Family    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
 UniProt Gene Name    PLCB1 [Similar Products]
 UniProt Synonym Gene Names    KIAA0581; PLC-I; PLC-beta-1 [Similar Products]
 UniProt Entry Name    PLCB1_HUMAN
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 NCBI Summary for PLCB1    The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PLCB1    PLCB1: an enzyme that catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. Binds to calmodulin. Uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variant isoforms have been described.

Protein type: Phospholipase; Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11

Chromosomal Location of Human Ortholog: 20p12

Cellular Component: nuclear membrane; cytoplasm; nuclear chromatin; nuclear speck; nucleus; cytosol

Molecular Function: calmodulin binding; signal transducer activity; phosphatidylinositol-4,5-bisphosphate binding; enzyme binding; protein homodimerization activity; calcium ion binding; phosphoinositide phospholipase C activity; GTPase activator activity; lamin binding

Biological Process: fat cell differentiation; positive regulation of developmental growth; acetylcholine receptor signaling, muscarinic pathway; inositol phosphate metabolic process; positive regulation of interleukin-12 production; glutamate signaling pathway; metabolic process; positive regulation of transcription, DNA-dependent; positive regulation of JNK cascade; signal transduction; memory; positive regulation of myoblast differentiation; synaptic transmission; positive regulation of embryonic development; insulin-like growth factor receptor signaling pathway; cerebral cortex development; phosphatidylinositol metabolic process; negative regulation of transcription, DNA-dependent; G2/M transition of mitotic cell cycle; lipid catabolic process; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity

Disease: Epileptic Encephalopathy, Early Infantile, 12
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 Research Articles on PLCB1    1. PLC-beta1 and DAGL-alpha are detected in discrete brain regions, with a marked predominance of pyramidal morphologies of positive cortical cells.[review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PLCB1 elisa kitDiseases associated with PLCB1 elisa kit
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Acetylcholine Regulates Insulin Secretion Pathway antibodies  Acetylcholine Regulates Insulin Secretion Pathway Diagram
 Activation Of Kainate Receptors Upon Glutamate Binding Pathway antibodies  Activation Of Kainate Receptors Upon Glutamate Binding Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimers Disease Pathway antibodies  Alzheimers Disease Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >10 publications with PLCB1 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >9 publications with PLCB1 and Disease Models, Animal
 Schizophrenia Antibodies  >8 publications with PLCB1 and Schizophrenia
 Hypertrophy Antibodies  >8 publications with PLCB1 and Hypertrophy
 Myelodysplastic Syndromes Antibodies  >7 publications with PLCB1 and Myelodysplastic Syndromes
 Heart Diseases Antibodies  >6 publications with PLCB1 and Heart Diseases
 Seizures Antibodies  >6 publications with PLCB1 and Seizures
 Hypertension Antibodies  >3 publications with PLCB1 and Hypertension
 Poisoning Antibodies  >2 publications with PLCB1 and Poisoning
 Edema Antibodies  >2 publications with PLCB1 and Edema
Organs/Tissues associated with PLCB1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >55 publications with PLCB1 and Brain
 Muscle Antibodies  >23 publications with PLCB1 and Muscle
 Nerve Antibodies  >9 publications with PLCB1 and Nerve
 Ovary Antibodies  >4 publications with PLCB1 and Ovary
 Kidney Antibodies  >4 publications with PLCB1 and Kidney
 Pancreas Antibodies  >4 publications with PLCB1 and Pancreas
 Lung Antibodies  >4 publications with PLCB1 and Lung
 Intestine Antibodies  >3 publications with PLCB1 and Intestine
 Mouth Antibodies  >2 publications with PLCB1 and Mouth
 Uterus Antibodies  >2 publications with PLCB1 and Uterus
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