NP_001121646.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,438 Da
NCBI Official Full Name
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
NCBI Official Synonym Full Names
UDP glycosyltransferase 8
NCBI Official Synonym Symbols
NCBI Protein Information
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
UniProt Protein Name
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
UniProt Synonym Protein Names
Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose-ceramide galactosyltransferase
UniProt Synonym Gene Names
NCBI Summary for UGT8
The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
UniProt Comments for UGT8
UGT8: Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Belongs to the UDP-glycosyltransferase family.
Protein type: EC 2.4.1.45; Lipid Metabolism - sphingolipid; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 4q26
Cellular Component: intracellular membrane-bound organelle; plasma membrane
Molecular Function: glucuronosyltransferase activity; N-acylsphingosine galactosyltransferase activity
Biological Process: central nervous system development; glycosphingolipid metabolic process; peripheral nervous system development
Research Articles on UGT8
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Products associated with UGT8 elisa kit
Pathways associated with UGT8 elisa kit
Diseases associated with UGT8 elisa kit
Organs/Tissues associated with UGT8 elisa kit
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