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MTHFS elisa kit :: Human 5, 10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9341493 MTHFS elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

5, 10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) (MTHFS), ELISA Kit

 Also Known As   

Human 5-formyltetrahydrofolate cyclo-ligase, MTHFS ELISA Kit

 Product Synonym Names    Human 5-formyltetrahydrofolate cyclo-ligase (MTHFS) ELISA kit; FLJ30410; HsT19268; ; 5; 10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
 Product Gene Name   

MTHFS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    604197
 3D Structure    ModBase 3D Structure for P49914
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MTHFS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MTHFS purchase    MBS9341493 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 5, 10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) (MTHFS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MTHFS. The ELISA analytical biochemical technique of the MBS9341493 kit is based on MTHFS antibody-MTHFS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MTHFS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MTHFS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MTHFS. It may not necessarily be applicable to this product.
 NCBI GI #    315113868
 NCBI GeneID    10588
 NCBI Accession #    NP_001186687.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199758.1 [Other Products]
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 UniProt Primary Accession #    P49914 [Other Products]
 UniProt Secondary Accession #    H3BQ75 [Other Products]
 UniProt Related Accession #    P49914 [Other Products]
 Molecular Weight    23,256 Da
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 NCBI Official Full Name    5-formyltetrahydrofolate cyclo-ligase isoform b
 NCBI Official Synonym Full Names    5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
 NCBI Official Symbol    MTHFS [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    5-formyltetrahydrofolate cyclo-ligase; methenyl-THF synthetase
 UniProt Protein Name    5-formyltetrahydrofolate cyclo-ligase
 UniProt Synonym Protein Names   
5,10-methenyl-tetrahydrofolate synthetase; MTHFS; Methenyl-THF synthetase
 UniProt Gene Name    MTHFS [Similar Products]
 UniProt Synonym Gene Names    MTHFS; Methenyl-THF synthetase [Similar Products]
 UniProt Entry Name    MTHFS_HUMAN
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 NCBI Summary for MTHFS    The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
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 UniProt Comments for MTHFS    Function: Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.

Catalytic activity: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate.

Cofactor: Magnesium.
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 Research Articles on MTHFS    1. The intronic Single nucleotide polymorphism in MTHFS had no significant effect on the risk of diabetic nephropathy in Taiwanese patients with T2D.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MTHFS elisa kitDiseases associated with MTHFS elisa kit
 Products by Pathway  Pathway Diagram
 One Carbon Metabolism Pathway antibodies  One Carbon Metabolism Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >10 publications with MTHFS and Neoplasms
 Immune System Diseases Antibodies  >3 publications with MTHFS and Immune System Diseases
 Neural Tube Defects Antibodies  >2 publications with MTHFS and Neural Tube Defects
 Kidney Diseases Antibodies  >2 publications with MTHFS and Kidney Diseases
 Gastrointestinal Diseases Antibodies  >1 publications with MTHFS and Gastrointestinal Diseases
 Ovarian Neoplasms Antibodies  >1 publications with MTHFS and Ovarian Neoplasms
 Liver Neoplasms Antibodies  >1 publications with MTHFS and Liver Neoplasms
 Cleft Lip Antibodies  >1 publications with MTHFS and Cleft Lip
 Cleft Palate Antibodies  >1 publications with MTHFS and Cleft Palate
Organs/Tissues associated with MTHFS elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with MTHFS and Liver
 Kidney Antibodies  >2 publications with MTHFS and Kidney
 Heart Antibodies  >1 publications with MTHFS and Heart
 Blood Antibodies  >1 publications with MTHFS and Blood
 Lung Antibodies  >1 publications with MTHFS and Lung
 Placenta Antibodies  >1 publications with MTHFS and Placenta
 Embryonic Tissue Antibodies  >1 publications with MTHFS and Embryonic Tissue
 Brain Antibodies  >1 publications with MTHFS and Brain
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