CAH03197.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
46,107 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1A
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
NCBI Official Synonym Symbols
G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1 [Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 1A; 5-HT1a receptor; guanine nucleotide-binding regulatory protein-coupled receptor
UniProt Protein Name
5-hydroxytryptamine (Serotonin) receptor 1A
UniProt Synonym Protein Names
5-hydroxytryptamine (Serotonin) receptor 1A; 5-hydroxytryptamine receptor 1A
UniProt Synonym Gene Names
UniProt Entry Name
Q5ZGX3_HUMAN
NCBI Summary for 5-ht
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
UniProt Comments for 5-ht
5-HT(1A): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family. 5- hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 5q11.2-q13
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding; serotonin receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; vasoconstriction; cell proliferation; behavioral fear response; serotonin receptor, adenylate cyclase inhibiting pathway; positive regulation of cell proliferation; regulation of serotonin secretion; regulation of dopamine metabolic process; regulation of hormone secretion; serotonin receptor signaling pathway; serotonin metabolic process; regulation of behavior
Disease: Periodic Fever, Menstrual Cycle-dependent
Research Articles on 5-ht
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Pathways associated with 5-ht elisa kit
Diseases associated with 5-ht elisa kit
Organs/Tissues associated with 5-ht elisa kit
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