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HTR2B elisa kit :: Human 5-hydroxytryptamine (serotonin) receptor 2B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9316816 HTR2B elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), ELISA Kit

★Popular Item★
 Also Known As   

Human 5-hydroxytryptamine receptor 2B, HTR2B ELISA Kit

 Product Synonym Names    Human 5-hydroxytryptamine receptor 2B (HTR2B) ELISA kit; 5-HT (2B); 5-HT2B; 5-HT 2B receptor; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine (serotonin) receptor 2B
 Product Gene Name   

HTR2B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    601122
 3D Structure    ModBase 3D Structure for P41595
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Sandwich (Quantitative)
 Detection Range    6.25ng/ml-200ng/ml.
 Sensitivity    1.0ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HTR2B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HTR2B purchase    MBS9316816 is a ready-to-use microwell, strip plate Sandwich (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 6.25ng/ml-200ng/ml in biological research samples containing HTR2B, with an estimated sensitivity of 1.0ng/ml. The ELISA analytical biochemical technique of the MBS9316816 kit is based on HTR2B antibody-HTR2B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HTR2B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HTR2B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for HTR2B elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HTR2B (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9316816. Click to request current manual
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NCBI/Uniprot data below describe general gene information for HTR2B. It may not necessarily be applicable to this product.
 NCBI GI #    222080049
 NCBI GeneID    3357
 NCBI Accession #    NP_000858.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000867.4 [Other Products]
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 UniProt Primary Accession #    P41595 [Other Products]
 UniProt Secondary Accession #    Q53TI1; Q62221; Q6P523; B2R9D5 [Other Products]
 UniProt Related Accession #    P41595; AAB31827 [Other Products]
 Molecular Weight    54,298 Da
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 NCBI Official Full Name    5-hydroxytryptamine receptor 2B
 NCBI Official Synonym Full Names    5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
 NCBI Official Symbol    HTR2B [Similar Products]
 NCBI Official Synonym Symbols   
5-HT2B; 5-HT(2B)
[Similar Products]
 NCBI Protein Information    5-hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT 2B receptor; serotonin receptor 2B; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine receptor 2B variant b
 UniProt Protein Name    5-hydroxytryptamine receptor 2B
 UniProt Synonym Protein Names   
Serotonin receptor 2B
 UniProt Gene Name    HTR2B [Similar Products]
 UniProt Synonym Gene Names    5-HT-2B; 5-HT2B [Similar Products]
 UniProt Entry Name    5HT2B_HUMAN
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 NCBI Summary for HTR2B    This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
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 UniProt Comments for HTR2B    5-HT(2B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q36.3-q37.1

Cellular Component: neuron projection; integral to plasma membrane; cytoplasm; plasma membrane; synapse; cell junction

Molecular Function: serotonin binding; serotonin receptor activity; G-protein alpha-subunit binding; drug binding

Biological Process: heart morphogenesis; negative regulation of autophagy; cGMP biosynthetic process; phosphoinositide 3-kinase cascade; intestine smooth muscle contraction; behavior; positive regulation of MAP kinase activity; positive regulation of cell proliferation; protein kinase C activation; neural crest cell differentiation; embryonic morphogenesis; neural crest cell migration; serotonin receptor signaling pathway; regulation of behavior; response to drug; positive regulation of cytokine production; vasoconstriction; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of nitric-oxide synthase activity; calcium-mediated signaling; positive regulation of phosphatidylinositol biosynthetic process; cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway; G-protein coupled receptor internalization; phospholipase C activation; release of sequestered calcium ion into cytosol; positive regulation of cell division; positive regulation of endothelial cell proliferation; phosphorylation; negative regulation of apoptosis; positive regulation of cytokine secretion
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 Research Articles on HTR2B    1. Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with HTR2B elisa kitDiseases associated with HTR2B elisa kit
 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4 publications with HTR2B and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with HTR2B and Brain Diseases
 Obesity Antibodies  >3 publications with HTR2B and Obesity
 Mental Disorders Antibodies  >3 publications with HTR2B and Mental Disorders
 Serotonin Syndrome Antibodies  >2 publications with HTR2B and Serotonin Syndrome
 Neurologic Manifestations Antibodies  >1 publications with HTR2B and Neurologic Manifestations
 Liver Diseases Antibodies  >1 publications with HTR2B and Liver Diseases
 Migraine Disorders Antibodies  >1 publications with HTR2B and Migraine Disorders
 Obsessive-Compulsive Disorder Antibodies  >1 publications with HTR2B and Obsessive-Compulsive Disorder
 Anxiety Disorders Antibodies  >1 publications with HTR2B and Anxiety Disorders
Organs/Tissues associated with HTR2B elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with HTR2B and Brain
 Intestine Antibodies  >4 publications with HTR2B and Intestine
 Vascular Antibodies  >4 publications with HTR2B and Vascular
 Blood Antibodies  >3 publications with HTR2B and Blood
 Prostate Antibodies  >2 publications with HTR2B and Prostate
 Ovary Antibodies  >1 publications with HTR2B and Ovary
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