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ADAMTS17 elisa kit :: Human ADAM metallopeptidase with thrombospondin type 1 motif, 17 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS941683 ADAMTS17 elisa kit
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAM metallopeptidase with thrombospondin type 1 motif, 17 (ADAMTS17), ELISA Kit

 Also Known As   

Human A disintegrin and metalloproteinase with thrombospondin motifs 17, ADAMTS17 ELISA Kit

 Product Synonym Names    Human A disintegrin and metalloproteinase with thrombospondin motifs 17 (ADAMTS17) ELISA kit; FLJ16363; FLJ32769; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 17; ADAM metallopeptidase with thrombospondin type 1 motif; 17
 Product Gene Name   

ADAMTS17 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 613195
 3D Structure    ModBase 3D Structure for Q8TE56
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human ADAMTS17. No significant cross-reactivity or interference between human ADAMTS17 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates.
 Assay Type    Sandwich (Quantitative)
 Detection Range    1.56 ng/ml - 100 ng/ml.
 Sensitivity    0.39 ng/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADAMTS17 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADAMTS17 purchase    MBS941683 is a ready-to-use microwell, strip plate Sandwich (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ADAM metallopeptidase with thrombospondin type 1 motif, 17 (ADAMTS17) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.56 ng/ml - 100 ng/ml in biological research samples containing ADAMTS17, with an estimated sensitivity of 0.39 ng/ml. The ELISA analytical biochemical technique of the MBS941683 kit is based on ADAMTS17 antibody-ADAMTS17 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAMTS17 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAMTS17. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for ADAMTS17 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADAMTS17 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADAMTS17 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADAMTS17 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADAMTS17 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS941683. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ADAMTS17. It may not necessarily be applicable to this product.
 NCBI GI #    110611170
 NCBI GeneID    170691
 NCBI Accession #    NP_620688.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_139057.2 [Other Products]
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 UniProt Primary Accession #    Q8TE56 [Other Products]
 UniProt Secondary Accession #    Q2I7G4; Q6ZN75 [Other Products]
 UniProt Related Accession #    Q8TE56 [Other Products]
 Molecular Weight    121,127 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 17 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif, 17
 NCBI Official Symbol    ADAMTS17 [Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 17; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 17
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    ADAMTS17 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 17; ADAM-TS17; ADAMTS-17 [Similar Products]
 UniProt Entry Name    ATS17_HUMAN
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 NCBI Summary for ADAMTS17    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAMTS17    ADAMTS17: Defects in ADAMTS17 are the cause of Weill-Marchesani- like syndrome (WMLS). It is a disorder characterized by many of the key features of Weill-Marchesani syndrome, including lenticular myopia, ectopia lentis, glaucoma, spherophakia and short stature. However, the characteristic brachydactyly or decreased joint flexibility of Weill-Marchesani syndrome are absent. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.24.-; Secreted, signal peptide; Protease; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: proteinaceous extracellular matrix

Molecular Function: zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis

Disease: Weill-marchesani-like Syndrome
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 Research Articles on ADAMTS17    1. A mutation in WMS-like gene ADAMTS17 also causes WMS.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with ADAMTS17 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >2 publications with ADAMTS17 and Connective Tissue
 Lung Antibodies  >1 publications with ADAMTS17 and Lung
 Skin Antibodies  >1 publications with ADAMTS17 and Skin
 Mammary Gland Antibodies  >1 publications with ADAMTS17 and Mammary Gland
 Brain Antibodies  >1 publications with ADAMTS17 and Brain
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