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ADAMTSL4 elisa kit :: Human ADAMTS-like 4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS931950
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAMTS-like 4 (ADAMTSL4), ELISA Kit

★Popular Item★
 Also Known As   

Human ADAMTS-like protein 4, ADAMTSL4 ELISA Kit

 Product Synonym Names    Human ADAMTS-like protein 4 (ADAMTSL4) ELISA kit; TSRC1; OTTHUMP00000032789; thrombospondin repeat containing 1; ADAMTS-like 4
 Product Gene Name   

ADAMTSL4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS931950 Testing Data    Testing Data PDF
 OMIM    610113
 3D Structure    ModBase 3D Structure for Q6UY14
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human ADAMTSL4. No significant cross-reactivity or interference between Human ADAMTSL4 and analogues was observed.
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 Assay Type    Sandwich
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Apoptosis/Autophagy
 Protein Biological Process 3    Apoptosis
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADAMTSL4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADAMTSL4 purchase    MBS931950 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ADAMTS-like 4 (ADAMTSL4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADAMTSL4. The ELISA analytical biochemical technique of the MBS931950 kit is based on ADAMTSL4 antibody-ADAMTSL4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAMTSL4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAMTSL4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for ADAMTSL4 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADAMTSL4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADAMTSL4 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADAMTSL4 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADAMTSL4 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of ADAMTSL4 elisa kit    ADAMTSL4 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS931950. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ADAMTSL4. It may not necessarily be applicable to this product.
 NCBI GI #    568384851
 NCBI GeneID    54507
 NCBI Accession #    NP_001275536.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001288607.1 [Other Products]
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 UniProt Primary Accession #    Q6UY14 [Other Products]
 UniProt Secondary Accession #    Q5T5F7; Q6IPM6; Q8N643; Q9HBS6; B2RTT0; F8WAD0 [Other Products]
 UniProt Related Accession #    Q6UY14 [Other Products]
 Molecular Weight    116,545 Da
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 NCBI Official Full Name    ADAMTS-like protein 4 isoform 3
 NCBI Official Synonym Full Names    ADAMTS-like 4
 NCBI Official Symbol    ADAMTSL4 [Similar Products]
 NCBI Official Synonym Symbols   
TSRC1; ECTOL2; ADAMTSL-4
[Similar Products]
 NCBI Protein Information    ADAMTS-like protein 4; thrombospondin repeat-containing protein 1
 UniProt Protein Name    ADAMTS-like protein 4
 UniProt Synonym Protein Names   
Thrombospondin repeat-containing protein 1
 Protein Family    ADAMTS-like protein
 UniProt Gene Name    ADAMTSL4 [Similar Products]
 UniProt Synonym Gene Names    TSRC1; PP1396; UNQ2803/PRO34012; ADAMTSL-4 [Similar Products]
 UniProt Entry Name    ATL4_HUMAN
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 NCBI Summary for ADAMTSL4    This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014]
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 UniProt Comments for ADAMTSL4    TSRC1: Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis. Defects in ADAMTSL4 are a cause of autosomal recessive isolated ectopia lentis (ARI-EL). ARI-EL is a rare condition characterized by partial or complete displacement of the lens from its space resulting from defective zonule formation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: endoplasmic reticulum lumen

Molecular Function: protein binding; protease binding; metalloendopeptidase activity

Biological Process: protein amino acid O-linked glycosylation; extracellular matrix organization and biogenesis; cellular protein metabolic process; positive regulation of apoptosis; apoptosis; proteolysis; post-translational protein modification

Disease: Ectopia Lentis 2, Isolated, Autosomal Recessive; Ectopia Lentis Et Pupillae
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 Research Articles on ADAMTSL4    1. We have confirmed the gene and protein expression of ADAMTSL4 in human ocular tissue. The pattern of expression may suggest further functions of this gene beyond those suggested by its causative role in isolated ectopia lentis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ADAMTSL4 elisa kitDiseases associated with ADAMTSL4 elisa kit
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-glycosylation Of TSR Domain-containing Proteins Pathway antibodies  O-glycosylation Of TSR Domain-containing Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Disease Name  Pubmed Publications
 Musculoskeletal Diseases Antibodies  >3 publications with ADAMTSL4 and Musculoskeletal Diseases
 Cardiovascular Diseases Antibodies  >2 publications with ADAMTSL4 and Cardiovascular Diseases
 Heart Diseases Antibodies  >2 publications with ADAMTSL4 and Heart Diseases
 Immune System Diseases Antibodies  >1 publications with ADAMTSL4 and Immune System Diseases
 Ovarian Neoplasms Antibodies  >1 publications with ADAMTSL4 and Ovarian Neoplasms
 Necrosis Antibodies  >1 publications with ADAMTSL4 and Necrosis
 ECTOPIA LENTIS 2, ISOLATED, AUTOSOMAL RECESSIVE Antibodies  >1 publications with ADAMTSL4 and ECTOPIA LENTIS 2, ISOLATED, AUTOSOMAL RECESSIVE
Organs/Tissues associated with ADAMTSL4 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >7 publications with ADAMTSL4 and Eye
 Blood Antibodies  >2 publications with ADAMTSL4 and Blood
 Connective Tissue Antibodies  >2 publications with ADAMTSL4 and Connective Tissue
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