NP_004325.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,326 Da
NCBI Official Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
NCBI Official Synonym Full Names
bone marrow stromal cell antigen 1
NCBI Official Synonym Symbols
NCBI Protein Information
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
UniProt Protein Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
UniProt Synonym Protein Names
ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD_antigen: CD157
UniProt Synonym Gene Names
UniProt Entry Name
BST1_HUMAN
NCBI Summary for BST1
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
UniProt Comments for BST1
BST1: Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. Belongs to the ADP-ribosyl cyclase family.
Protein type: Membrane protein, GPI anchor; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Hydrolase; EC 3.2.2.6
Chromosomal Location of Human Ortholog: 4p15
Cellular Component: extrinsic to membrane; plasma membrane
Molecular Function: NAD(P)+ nucleosidase activity; NAD+ nucleosidase activity; phosphorus-oxygen lyase activity; transferase activity
Biological Process: humoral immune response; metabolic process; multicellular organismal development; positive regulation of B cell proliferation
Research Articles on BST1
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Products associated with BST1 elisa kit
Pathways associated with BST1 elisa kit
Diseases associated with BST1 elisa kit
Organs/Tissues associated with BST1 elisa kit
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