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ARFGAP1 elisa kit :: Human ADP-ribosylation factor GTPase activating protein 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9336072 ARFGAP1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1), ELISA Kit

 Also Known As   

Human ADP-ribosylation factor GTPase-activating protein 1, ARFGAP1 ELISA Kit

 Product Synonym Names    Human ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) ELISA kit; ARF1GAP; HRIHFB2281; MGC39924; ADP-ribosylation factor 1 GTPase activating protein; ARF1-directed GTPase-activating protein; GAP protein; ADP-ribosylation factor GTPase activating protein 1
 Product Gene Name   

ARFGAP1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    608377
 3D Structure    ModBase 3D Structure for Q8N6T3
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ARFGAP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ARFGAP1 purchase    MBS9336072 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ARFGAP1. The ELISA analytical biochemical technique of the MBS9336072 kit is based on ARFGAP1 antibody-ARFGAP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ARFGAP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ARFGAP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ARFGAP1. It may not necessarily be applicable to this product.
 NCBI GI #    527498254
 NCBI GeneID    55738
 NCBI Accession #    NP_001268411.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001281482.1 [Other Products]
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 UniProt Primary Accession #    Q8N6T3 [Other Products]
 UniProt Secondary Accession #    Q6PK71; Q96KC4; Q96T02; Q9NSU3; Q9NVF6; Q9UIL0; B7Z3U0; B7Z8H8; B7ZBI3; E1P5I9; E7EV62 [Other Products]
 UniProt Related Accession #    Q8N6T3 [Other Products]
 Molecular Weight    44,668 Da
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 NCBI Official Full Name    ADP-ribosylation factor GTPase-activating protein 1 isoform c
 NCBI Official Synonym Full Names    ADP-ribosylation factor GTPase activating protein 1
 NCBI Official Symbol    ARFGAP1 [Similar Products]
 NCBI Official Synonym Symbols   
ARF1GAP; HRIHFB2281
[Similar Products]
 NCBI Protein Information    ADP-ribosylation factor GTPase-activating protein 1; ARF1-directed GTPase-activating protein
 UniProt Protein Name    ADP-ribosylation factor GTPase-activating protein 1
 UniProt Synonym Protein Names   
ADP-ribosylation factor 1 GTPase-activating protein; ARF1 GAP; ARF1-directed GTPase-activating protein
 Protein Family    ADP-ribosylation factor GTPase-activating protein
 UniProt Gene Name    ARFGAP1 [Similar Products]
 UniProt Synonym Gene Names    ARF1GAP; ARF GAP 1; ARF1 GAP [Similar Products]
 UniProt Entry Name    ARFG1_HUMAN
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 NCBI Summary for ARFGAP1    The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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 UniProt Comments for ARFGAP1    ARF GAP1: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; GAPs; GAPs, ARF

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: synapse; cytosol

Molecular Function: protein binding; zinc ion binding; GTPase activator activity

Biological Process: protein transport; COPI coating of Golgi vesicle; cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; unfolded protein response; retrograde vesicle-mediated transport, Golgi to ER; positive regulation of GTPase activity
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 Research Articles on ARFGAP1    1. ARFGAP1 is a host factor for Hepatitis C Virus RNA replication, and is hijacked by HCV NS5A to remove COPI cargo Sac1 from the site of HCV replication to maintain high levels of PI4P.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ARFGAP1 elisa kitPathways associated with ARFGAP1 elisa kit
 Reference Product  PubMed Publications
 ARF1 elisa kit  >30 publications with ARFGAP1 and ARF1
 Products by Pathway  Pathway Diagram
 Activation Of Chaperone Genes By XBP1(S) Pathway antibodies  Activation Of Chaperone Genes By XBP1(S) Pathway Diagram
 Activation Of Chaperones By IRE1alpha Pathway antibodies  Activation Of Chaperones By IRE1alpha Pathway Diagram
 Arf1 Pathway antibodies  Arf1 Pathway Diagram
 COPI Mediated Transport Pathway antibodies  COPI Mediated Transport Pathway Diagram
 Diabetes Pathways antibodies  Diabetes Pathways Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Golgi To ER Retrograde Transport Pathway antibodies  Golgi To ER Retrograde Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
Diseases associated with ARFGAP1 elisa kitOrgans/Tissues associated with ARFGAP1 elisa kit
 Disease Name  Pubmed Publications
 Neurologic Manifestations Antibodies  >2 publications with ARFGAP1 and Neurologic Manifestations
 Neurobehavioral Manifestations Antibodies  >2 publications with ARFGAP1 and Neurobehavioral Manifestations
 Nervous System Diseases Antibodies  >2 publications with ARFGAP1 and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with ARFGAP1 and Brain Diseases
 Seizures Antibodies  >1 publications with ARFGAP1 and Seizures
 Developmental Disabilities Antibodies  >1 publications with ARFGAP1 and Developmental Disabilities
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with ARFGAP1 and Brain
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