NP_036238.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,822 Da
NCBI Official Full Name
ADP-ribosylation factor-like protein 2-binding protein
NCBI Official Synonym Full Names
ADP-ribosylation factor-like 2 binding protein
NCBI Protein Information
ADP-ribosylation factor-like protein 2-binding protein; binder of Arl2; binder of Arl Two; ARL2-binding protein; binder of ARF2 protein 1; ARF-like 2-binding protein; Arf-like 2 binding protein BART1; retinitis pigmentosa 66 (autosomal recessive)
UniProt Protein Name
ADP-ribosylation factor-like protein 2-binding protein
UniProt Synonym Protein Names
Binder of ARF2 protein 1
UniProt Synonym Gene Names
BART; BART1; ARF-like 2-binding protein; ARL2-binding protein [Similar Products]
UniProt Entry Name
AR2BP_HUMAN
NCBI Summary for ARL2BP
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
UniProt Comments for ARL2BP
ARL2BP: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. Belongs to the ARL2BP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial; G protein regulator, misc.
Chromosomal Location of Human Ortholog: 16q13
Cellular Component: centrosome; mitochondrial intermembrane space; spindle; midbody; nucleus; cilium
Molecular Function: protein binding; transcription coactivator activity
Biological Process: regulation of catalytic activity; maintenance of protein localization in nucleus; signal transduction; positive regulation of tyrosine phosphorylation of Stat3 protein
Disease: Retinitis Pigmentosa With Or Without Situs Inversus
Research Articles on ARL2BP
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with ARL2BP elisa kit
Diseases associated with ARL2BP elisa kit
Organs/Tissues associated with ARL2BP elisa kit
|