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AQP-4 elisa kit :: Human AQP-4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2503752
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Human AQP-4 (Aquaporin 4) ELISA Kit

 Product Gene Name   

AQP-4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P55088
 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human AQP-4. No significant cross-reactivity or interference between Human AQP-4 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human AQP-4 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    Min: 0.188ng/mL; Max: 20ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AQP-4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AQP-4 purchase    MBS2503752 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the AQP-4, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313-20ng/mL in biological research samples containing AQP-4, with an estimated sensitivity of Min: 0.188ng/mL; Max: 20ng/mL. The ELISA analytical biochemical technique of the MBS2503752 kit is based on AQP-4 antibody-AQP-4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AQP-4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AQP-4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for AQP-4 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of AQP-4 in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human AQP-4. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human AQP-4 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human AQP-4, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human AQP-4. You can calculate the concentration of Human AQP-4 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of AQP-4 elisa kit    AQP-4 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2503752. Click to request current manual
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NCBI/Uniprot data below describe general gene information for AQP-4. It may not necessarily be applicable to this product.
 NCBI GI #    160415211
 NCBI GeneID    11829
 NCBI Accession #    NP_033830.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_009700.2 [Other Products]
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 UniProt Primary Accession #    P55088 [Other Products]
 UniProt Secondary Accession #    P97818; Q4FJP1; Q61131; Q61132; Q8VHE4; Q8VHE5; Q9EQI3 [Other Products]
 UniProt Related Accession #    P55088 [Other Products]
 Molecular Weight    37,977 Da
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 NCBI Official Full Name    aquaporin-4
 NCBI Official Synonym Full Names    aquaporin 4
 NCBI Official Symbol    Aqp4 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    aquaporin-4; AQP-4; mercurial-insensitive water channel
 UniProt Protein Name    Aquaporin-4
 UniProt Synonym Protein Names   
Mercurial-insensitive water channel; MIWC; WCH4
 UniProt Gene Name    Aqp4 [Similar Products]
 UniProt Synonym Gene Names    AQP-4; MIWC [Similar Products]
 UniProt Entry Name    AQP4_MOUSE
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 UniProt Comments for AQP-4    AQP4: a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The predominant aquaporin found in brain. Two alternatively spliced transcript variants have been described

Protein type: Membrane protein, multi-pass; Channel, misc.; Transporter, aquaporin family; Membrane protein, integral; Transporter

Cellular Component: membrane; integral to plasma membrane; basolateral plasma membrane; cell; cytoplasm; integral to membrane; plasma membrane; intercellular junction

Molecular Function: transporter activity; water channel activity; glycerol channel activity

Biological Process: water homeostasis; glycerol transport; cellular water homeostasis; sensory perception of sound; transport; cellular response to stress; water transport; transmembrane transport
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 Research Articles on AQP-4    1. AQP4 mitigates spinal cord damage and ameliorates retrograde degeneration of rubrospinal neurons by promoting edema clearance and glial scar formation after spinal cord injury.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AQP-4 elisa kitDiseases associated with AQP-4 elisa kit
 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Passive Transport By Aquaporins Pathway antibodies  Passive Transport By Aquaporins Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Vasopressin Regulates Renal Water Homeostasis Via Aquaporins Pathway antibodies  Vasopressin Regulates Renal Water Homeostasis Via Aquaporins Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >935 publications with AQP-4 and Nervous System Diseases
 Neuromyelitis Optica Antibodies  >558 publications with AQP-4 and Neuromyelitis Optica
 Brain Diseases Antibodies  >468 publications with AQP-4 and Brain Diseases
 Edema Antibodies  >457 publications with AQP-4 and Edema
 Brain Edema Antibodies  >390 publications with AQP-4 and Brain Edema
 Disease Models, Animal Antibodies  >206 publications with AQP-4 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >175 publications with AQP-4 and Cardiovascular Diseases
 Inflammation Antibodies  >122 publications with AQP-4 and Inflammation
 Necrosis Antibodies  >45 publications with AQP-4 and Necrosis
 Kidney Diseases Antibodies  >39 publications with AQP-4 and Kidney Diseases
Organs/Tissues associated with AQP-4 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >967 publications with AQP-4 and Brain
 Spinal Cord Antibodies  >282 publications with AQP-4 and Spinal Cord
 Eye Antibodies  >137 publications with AQP-4 and Eye
 Muscle Antibodies  >107 publications with AQP-4 and Muscle
 Lung Antibodies  >64 publications with AQP-4 and Lung
 Heart Antibodies  >37 publications with AQP-4 and Heart
 Intestine Antibodies  >27 publications with AQP-4 and Intestine
 Embryonic Tissue Antibodies  >25 publications with AQP-4 and Embryonic Tissue
 Thymus Antibodies  >6 publications with AQP-4 and Thymus
 Mammary Gland Antibodies  >2 publications with AQP-4 and Mammary Gland
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