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ARG2 elisa kit :: Human ARG2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2516353
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ARG2, ELISA Kit

★Popular Item★
 Also Known As   

Human ARG2 (Arginase II) ELISA Kit

 Product Gene Name   

ARG2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2516353 COA    COA PDF
 OMIM    107830
 3D Structure    ModBase 3D Structure for P78540
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and some recombinant Human ARG2. No significant cross-reactivity or interference between Human ARG2 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    3.125-200ng/mL
 Sensitivity    Min: 1.875ng/mL; Max: 200ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ARG2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ARG2 purchase    MBS2516353 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ARG2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.125-200ng/mL in biological research samples containing ARG2, with an estimated sensitivity of Min: 1.875ng/mL; Max: 200ng/mL. The ELISA analytical biochemical technique of the MBS2516353 kit is based on ARG2 antibody-ARG2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ARG2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ARG2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). Arginase exists in 2 isoforms. ARG1 generates urea from toxic ammonia but ARG type II is frequently associated with mitochondria and homeostasis of arginine in the cytosol. Arginase 2 is co-expressed with iNOS and regulates contractions of smooth muscle by ankyrin. Both cell and molecular biology research into these fascinating mechanisms require careful and selective quantitation of human protein samples. MyBiosource aids your analysis of sample proteins with a precision Arginase II sandwich ELISA kit. Our ELISA kits are shipped with all assay reagents needed - antibody bound plate, standard curve, secondary antibodies - enough for repeat samples. With ng ml dynamic range, your small molecule screens targeting tissue ARG2 Arginase will be robust. While you are at it, we recommend viewing related ELISA kits ArfGAP GTPase and domain ankyrin repeat or the specialized Arginase 2 mitochondrial kits. All our kits are top sellers worldwide, order at MyBiosource.com.
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Related Product Information for ARG2 elisa kit

   Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Human ARG2 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human ARG2. Standards or samples are added to appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibodies specific for Human ARG2 and Avidin- Horseradish Peroxidase (HRP) conjugate are added to each micro plate well successively and incubated. After incubation, free components are washed away. Then the Substrate Reagent is added to each well, only those wells that contain Human ARG2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzymesubstrate reaction will be terminated by adding Stop Solution and appears yellow in color. The optical density (OD) can be measured with spectrophotometry at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human ARG2. The concentration of Human ARG2 in samples can be calculated by comparing the OD of the samples with the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of ARG2 elisa kit    ARG2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2516353. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ARG2. It may not necessarily be applicable to this product.
 NCBI GI #    49168584
 NCBI GeneID    384
 NCBI Accession #    CAG38787.1 [Other Products]
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 UniProt Primary Accession #    P78540 [Other Products]
 UniProt Secondary Accession #    Q6FHY8; B2R690 [Other Products]
 UniProt Related Accession #    P78540 [Other Products]
 Molecular Weight    38,578 Da
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 NCBI Official Full Name    ARG2
 NCBI Official Synonym Full Names    arginase 2
 NCBI Official Symbol    ARG2 [Similar Products]
 NCBI Protein Information    arginase-2, mitochondrial; L-arginine amidinohydrolase; L-arginine ureahydrolase; arginase, type II; kidney arginase; kidney-type arginase; non-hepatic arginase; nonhepatic arginase; type II arginase
 UniProt Protein Name    Arginase-2, mitochondrial
 UniProt Synonym Protein Names   
Kidney-type arginase; Non-hepatic arginase; Type II arginase
 Protein Family    Arginase
 UniProt Gene Name    ARG2 [Similar Products]
 UniProt Entry Name    ARGI2_HUMAN
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 NCBI Summary for ARG2    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ARG2    ARG2: May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. Belongs to the arginase family.

Protein type: EC 3.5.3.1; Hydrolase; Mitochondrial; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: metal ion binding; arginase activity

Biological Process: striated muscle contraction; arginine metabolic process; ureteric bud development; nitric oxide biosynthetic process; urea cycle
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 Research Articles on ARG2    1. These results demonstrate that S6K1 and arginase-II form a positive circuit mediating the detrimental effects of chronic L-arginine supplementation on endothelial cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ARG2 elisa kitPathways associated with ARG2 elisa kit
 Reference Product  PubMed Publications
 NOS3 elisa kit  >19 publications with ARG2 and NOS3
 NOS2 elisa kit  >15 publications with ARG2 and NOS2
 NOS1 elisa kit  >10 publications with ARG2 and NOS1
 OAT elisa kit  >5 publications with ARG2 and OAT
 ASL elisa kit  >3 publications with ARG2 and ASL
 OTC elisa kit  >2 publications with ARG2 and OTC
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies  Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram
Diseases associated with ARG2 elisa kitOrgans/Tissues associated with ARG2 elisa kit
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >26 publications with ARG2 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >23 publications with ARG2 and Cardiovascular Diseases
 Inflammation Antibodies  >22 publications with ARG2 and Inflammation
 Nervous System Diseases Antibodies  >20 publications with ARG2 and Nervous System Diseases
 Lung Diseases Antibodies  >17 publications with ARG2 and Lung Diseases
 Brain Diseases Antibodies  >15 publications with ARG2 and Brain Diseases
 Asthma Antibodies  >12 publications with ARG2 and Asthma
 Hypertension Antibodies  >11 publications with ARG2 and Hypertension
 Kidney Diseases Antibodies  >10 publications with ARG2 and Kidney Diseases
 Heart Diseases Antibodies  >7 publications with ARG2 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >77 publications with ARG2 and Blood
 Brain Antibodies  >65 publications with ARG2 and Brain
 Vascular Antibodies  >42 publications with ARG2 and Vascular
 Muscle Antibodies  >42 publications with ARG2 and Muscle
 Kidney Antibodies  >31 publications with ARG2 and Kidney
 Lung Antibodies  >26 publications with ARG2 and Lung
 Intestine Antibodies  >24 publications with ARG2 and Intestine
 Liver Antibodies  >23 publications with ARG2 and Liver
 Pituitary Gland Antibodies  >22 publications with ARG2 and Pituitary Gland
 Heart Antibodies  >20 publications with ARG2 and Heart
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