NP_005054.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,523 Da
NCBI Official Full Name
acyl-CoA desaturase
NCBI Official Synonym Full Names
stearoyl-CoA desaturase (delta-9-desaturase)
NCBI Official Synonym Symbols
SCD1; FADS5; SCDOS; hSCD1; MSTP008 [Similar Products]
NCBI Protein Information
acyl-CoA desaturase
UniProt Protein Name
Acyl-CoA desaturase
UniProt Synonym Protein Names
Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase; Stearoyl-CoA desaturase
UniProt Synonym Gene Names
UniProt Entry Name
ACOD_HUMAN
NCBI Summary for SCD
This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]
UniProt Comments for SCD
SCD: Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Belongs to the fatty acid desaturase family.
Protein type: Oxidoreductase; Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, multi-pass; Endoplasmic reticulum; Membrane protein, integral; EC 1.14.19.1
Chromosomal Location of Human Ortholog: 10q24.31
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane
Molecular Function: iron ion binding; oxidoreductase activity; stearoyl-CoA 9-desaturase activity
Biological Process: cellular lipid metabolic process; triacylglycerol biosynthetic process; unsaturated fatty acid biosynthetic process
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Products associated with SCD elisa kit
Pathways associated with SCD elisa kit
Diseases associated with SCD elisa kit
Organs/Tissues associated with SCD elisa kit
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