NP_060708.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,634 Da
NCBI Official Full Name
acylglycerol kinase, mitochondrial
NCBI Official Synonym Full Names
acylglycerol kinase
NCBI Protein Information
acylglycerol kinase, mitochondrial
UniProt Protein Name
Acylglycerol kinase, mitochondrial
UniProt Synonym Protein Names
Multiple substrate lipid kinase; HsMuLK; MuLK; Multi-substrate lipid kinase
UniProt Synonym Gene Names
NCBI Summary for AGK
The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. The encoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects in this gene have been associated with mitochondrial DNA depletion syndrome 10. [provided by RefSeq, Feb 2012]
UniProt Comments for AGK
Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
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Pathways associated with AGK elisa kit
Diseases associated with AGK elisa kit
Organs/Tissues associated with AGK elisa kit
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